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Details on Person Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

Class:Id	LiteratureReference:5609775
_displayName	Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation
_timestamp	2014-07-16 20:07:53
author	[Person:5609774] Wen, Xiaohui [Person:5609773] Lai, Cary K [Person:5609772] Evangelista, Marie [Person:3640666] Hongo, Jo-Anne [Person:2399680] de Sauvage, Frederic J [Person:5609771] Scales, Suzie J
created	[InstanceEdit:5609776] Rothfels, Karen, 2014-07-16
journal	Mol. Cell. Biol.
pages	1910-22
pubMedIdentifier	20154143
title	Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation
volume	30
year	2010
(literatureReference)	[Reaction:5610720] PKA phosphorylates GLI3 [Homo sapiens] [Reaction:5610722] CK1 phosphorylates p-GLI3 [Homo sapiens] [Reaction:5610733] KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules [Homo sapiens] [BlackBoxEvent:5610766] The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base [Homo sapiens] [BlackBoxEvent:5610767] The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip [Homo sapiens] [Pathway:5610785] GLI3 is processed to GLI3R by the proteasome [Homo sapiens] [BlackBoxEvent:5635841] GLI proteins are phosphorylated [Homo sapiens] [BlackBoxEvent:5635843] GLI translocates to the nucleus [Homo sapiens] [BlackBoxEvent:5635854] GLI2,3 are degraded by the proteasome [Homo sapiens] [Reaction:5635855] phosphorylated GLI proteins bind SPOP:CUL3:RBX1 [Homo sapiens] List all 13 refering instances
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