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Details on Person A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes

Class:Id	LiteratureReference:5609686
_displayName	A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
_timestamp	2014-07-16 20:06:15
author	[Person:5358176] Tukachinsky, Hanna [Person:5609684] Lopez, Lyle V [Person:2500247] Salic, Adrian
created	[InstanceEdit:5609685] Rothfels, Karen, 2014-07-16
journal	J. Cell Biol.
pages	415-28
pubMedIdentifier	20956384
title	A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
volume	191
year	2010
(literatureReference)	[Reaction:5610723] GLI proteins bind SUFU [Homo sapiens] [Reaction:5610733] KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules [Homo sapiens] [BlackBoxEvent:5610766] The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base [Homo sapiens] [BlackBoxEvent:5610767] The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip [Homo sapiens] [BlackBoxEvent:5635102] GPR161 is internalized [Homo sapiens] [BlackBoxEvent:5635843] GLI translocates to the nucleus [Homo sapiens] [BlackBoxEvent:5635854] GLI2,3 are degraded by the proteasome [Homo sapiens] [Reaction:5635855] phosphorylated GLI proteins bind SPOP:CUL3:RBX1 [Homo sapiens] [Reaction:5635856] SPOP:CUL3:RBX1 ubiquitinates GLI2,3 [Homo sapiens] [Reaction:5635859] GLI:SUFU dissociates [Homo sapiens] List all 11 refering instances
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