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Details on Person Phospholipase C?2 (PLC?2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses
| Class:Id | LiteratureReference:5607371 |
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| _displayName | Phospholipase C?2 (PLC?2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses |
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| _timestamp | 2014-07-11 09:51:43 |
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| author | [Person:5607235] Gorjestani, Sara
[Person:3215082] Yu, Mei
[Person:5607150] Tang, Bing
[Person:112218] Zhang, D
[Person:2685009] Wang, Demin
[Person:2685081] Lin, Xin |
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| created | [InstanceEdit:5607215] Garapati, P V, 2014-07-11 |
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| journal | J. Biol. Chem. |
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| pages | 43651-9 |
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| pubMedIdentifier | 22041900 |
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| title | Phospholipase C?2 (PLC?2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses |
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| volume | 286 |
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| year | 2011 |
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| (literatureReference) | [Summation:5607592] Activation of SYK triggers multiple cascades, which induces ...
[Summation:5621350] Phospholipase C-gamma (PLCG) binds to phosphorylated Tyr-348...
[Summation:5621357] CLEC6A (C-type lectin domain family 6 member A/Dectin-2 (Den...
[Summation:5621364] Activation of SYK triggers multiple cascades, which induces ...
[Reaction:5621346] Plcg1 binds p-Y348,352,525,526-Syk [Mus musculus]
[Reaction:5621363] SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 [Homo sapiens]
[CatalystActivityReference:9643739] protein tyrosine kinase activity of pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane] Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk |
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