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Details on Person MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met

Class:Id	Reaction:5603114
_displayName	MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met
_doRelease	TRUE
_timestamp	2014-11-20 02:48:18
authored	[InstanceEdit:5603083] Jassal, Bijay, 2014-06-27
catalystActivity	[CatalystActivity:5603117] methionine adenosyltransferase activity of MAT2B:MAT2A:K+:2Mg2+ [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5603083] Jassal, Bijay, 2014-06-27
edited	[InstanceEdit:5603083] Jassal, Bijay, 2014-06-27
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:174390] L-Met [cytosol] [SimpleEntity:29356] H2O [cytosol]
literatureReference	[LiteratureReference:5603111] Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II) [LiteratureReference:5603123] Expression and functional interaction of the catalytic and regulatory subunits of human methionine adenosyltransferase in mammalian cells
modified	[InstanceEdit:5622015] Jassal, Bijay, 2014-09-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met AdoMet is sythesized from methionine's reaction with ATP
output	[SimpleEntity:71284] AdoMet [cytosol] [SimpleEntity:29372] Pi [cytosol] [SimpleEntity:111294] PPi [cytosol]
releaseDate	2014-09-30
reviewed	[InstanceEdit:377465] D'Eustachio, P, 2008-06-12 14:43:38
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644850] R-HSA-5603114.2
summation	[Summation:5603121] S-adenosylmethionine (AdoMet, SAM) is an essential metabolit...
(hasEvent)	[Pathway:156581] Methylation [Homo sapiens]
(precedingEvent)	[Reaction:158609] TPMT transfers CH3 from AdoMet to 6MP [Homo sapiens] [Reaction:175976] TMT transfers CH3 from AdoMet to BME [Homo sapiens] [Reaction:175983] COMT transfer CH3 from AdoMet to 3,4DHBNZ [Homo sapiens] [Reaction:175987] NNMT transfers CH3 from AdoMet to PY [Homo sapiens]
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No pathways have been reviewed or authored by MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (5603114)