Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person IRAK4 R12C [cytosol]

Class:IdEntityWithAccessionedSequence:5602511
_displayNameIRAK4 R12C [cytosol]
_timestamp2015-03-04 05:42:21
compartment[Compartment:70101] cytosol
created[InstanceEdit:5602721] Shamovsky, Veronica, 2014-06-24
endCoordinate460
hasModifiedResidue[ReplacedResidue:5602537] L-arginine 12 replaced with L-cysteine
nameIRAK4 R12C
referenceEntity[ReferenceGeneProduct:148936] UniProt:Q9NWZ3 IRAK4 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5681359] R-HSA-5602511.1
startCoordinate1
(diseaseEntity)[EntityFunctionalStatus:5602633] loss_of_function of IRAK4 R12C [cytosol]
(hasMember)[DefinedSet:5602412] IRAK4 variants [cytosol] [Homo sapiens]
(input)[FailedReaction:5602684] Defective IRAK4 does not form complex with MyD88 within TLR7/8 complex [Homo sapiens]
[FailedReaction:5602764] Defective IRAK4 does not form complex with MyD88 within TLR7/8 complex [Homo sapiens]
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No pathways have been reviewed or authored by IRAK4 R12C [cytosol] (5602511)