Query author contributions in Reactome
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Details on Person UniProt:P10620 MGST1
| Class:Id | ReferenceGeneProduct:56022 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-155 added on Sat February 7 2015 |
| _displayName | UniProt:P10620 MGST1 |
| _timestamp | 2025-02-21 18:38:50 |
| chain | chain:1-155 |
| checksum | 892A529C97E3C853 |
| comment | FUNCTION Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.CATALYTIC ACTIVITY RX + glutathione = an S-substituted glutathione + a halide anion + H(+)SUBUNIT Homotrimer; The trimer binds only one molecule of glutathione.INTERACTION Highly expressed in liver.SIMILARITY Belongs to the MAPEG family. |
| description | recommendedName: Microsomal glutathione S-transferase 1 shortName: Microsomal GST-1 ecNumber evidence="1"2.5.1.18 alternativeName: Microsomal GST-I |
| geneName | MGST1 GST12 MGST |
| identifier | P10620 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Alternative splicing Endoplasmic reticulum Membrane Mitochondrion Mitochondrion outer membrane Proteomics identification Reference proteome Transferase Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | MGST1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9004810] ENSEMBL:ENSG00000008394 MGST1 [Homo sapiens] |
| secondaryIdentifier | MGST1_HUMAN A8K533 G5EA53 |
| sequenceLength | 155 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8977930] UniProt:P10620-1 MGST1 [Homo sapiens] [ReferenceIsoform:8977931] UniProt:P10620-2 MGST1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:158545] MGST1 [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:6799226] MGST1 [azurophil granule membrane] [Homo sapiens] [EntityWithAccessionedSequence:6806259] MGST1 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P10620 MGST1 (56022)
