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Details on Person Mangelsdorf, David J

Class:Id	Person:5602153
_displayName	Mangelsdorf, David J
_timestamp	2014-06-20 12:05:14
created	[InstanceEdit:5602197] Jassal, Bijay, 2014-06-20
firstname	David J
initial	DJ
surname	Mangelsdorf
(author)	[LiteratureReference:8963867] De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase [LiteratureReference:9029535] Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta [LiteratureReference:9035126] Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta [LiteratureReference:9038020] 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen [LiteratureReference:9631281] Sterol-dependent nuclear import of ORP1S promotes LXR regulated trans-activation of apoE [LiteratureReference:9632988] Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue [LiteratureReference:9657837] Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network [LiteratureReference:9658350] LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice [LiteratureReference:9658381] LXRs regulate the balance between fat storage and oxidation [LiteratureReference:9859748] Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones
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No pathways have been reviewed or authored by Mangelsdorf, David J (5602153)