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Details on Person UniProt:P48507 GCLM
| Class:Id | ReferenceGeneProduct:55990 |
|---|---|
| _chainChangeLog | chain:1-274 added on Fri February 6 2015 |
| _displayName | UniProt:P48507 GCLM |
| _timestamp | 2024-11-03 20:19:19 |
| chain | chain:1-274 |
| checksum | 88F73E22322E40B2 |
| comment | PATHWAY Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.SUBUNIT Heterodimer of a catalytic heavy chain and a regulatory light chain.INTERACTION In all tissues examined. Highest levels in skeletal muscle.SIMILARITY Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily. |
| description | recommendedName: Glutamate--cysteine ligase regulatory subunit alternativeName: GCS light chain alternativeName: Gamma-ECS regulatory subunit alternativeName: Gamma-glutamylcysteine synthetase regulatory subunit alternativeName: Glutamate--cysteine ligase modifier subunit |
| geneName | GCLM GLCLR |
| identifier | P48507 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Alternative splicing Glutathione biosynthesis Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | GCLM |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9002980] ENSEMBL:ENSG00000023909 GCLM [Homo sapiens] |
| secondaryIdentifier | GSH0_HUMAN A8K334 D3DT45 M5A959 Q6FHC1 Q9NPX9 Q9NU74 |
| sequenceLength | 274 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8965624] UniProt:P48507-1 GCLM [Homo sapiens] [ReferenceIsoform:8965625] UniProt:P48507-2 GCLM [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:174356] GCLM [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P48507 GCLM (55990)
