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Query author contributions in Reactome

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Details on Person UniProt:Q02643 GHRHR

Class:IdReferenceGeneProduct:55948
_chainChangeLogsignal peptide:1-22 added on Fri February 6 2015;chain:23-423 added on Fri February 6 2015
_displayNameUniProt:Q02643 GHRHR
_timestamp2026-02-20 21:30:17
chainsignal peptide:1-22
chain:23-423
checksumC9C5E2E7D6649E06
commentFUNCTION Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.INTERACTION Pituitary gland.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the G-protein coupled receptor 2 family.
descriptionrecommendedName: Growth hormone-releasing hormone receptor shortName: GHRH receptor alternativeName: Growth hormone-releasing factor receptor shortName: GRF receptor shortName: GRFR
geneNameGHRHR
identifierQ02643
isSequenceChangedFALSE
keyword3D-structure
Cell membrane
Disease variant
Disulfide bond
Dwarfism
G-protein coupled receptor
Glycoprotein
Membrane
Receptor
Reference proteome
Signal
Transducer
Transmembrane
Transmembrane helix
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameGHRHR
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9003545] ENSEMBL:ENSG00000106128 GHRHR [Homo sapiens]
secondaryIdentifierGHRHR_HUMAN
Q99863
sequenceLength423
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:420079] GHRHR [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q02643 GHRHR (55948)