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Details on Person UniProt:Q99705 MCHR1
| Class:Id | ReferenceGeneProduct:55810 |
|---|---|
| _chainChangeLog | chain:1-422 added on Sat February 7 2015;chain:1-422 for 55810 removed on Mon Feb 26 2024;chain:1-353 for 55810 added on Mon Feb 26 2024 |
| _displayName | UniProt:Q99705 MCHR1 |
| _timestamp | 2024-11-03 20:06:09 |
| chain | chain:1-353 |
| checksum | 0C7D692C92667EDC |
| comment | FUNCTION Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.SUBUNIT Interacts with NCDN.SUBCELLULAR LOCATION Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart.SIMILARITY Belongs to the G-protein coupled receptor 1 family.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus.SEQUENCE CAUTION Extended N-terminus. |
| description | recommendedName: fullName evidence="10"Melanin-concentrating hormone receptor 1 shortName: MCH receptor 1 shortName: MCH-R1 shortName: MCHR-1 alternativeName: G-protein coupled receptor 24 alternativeName: MCH-1R shortName: MCH1R shortName: MCHR alternativeName: SLC-1 alternativeName: Somatostatin receptor-like protein |
| geneName | MCHR1 GPR24 SLC1 |
| identifier | Q99705 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9909836] Weiser, Joel, 2024-05-14 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MCHR1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8989061] ENSEMBL:ENSG00000128285 MCHR1 [Homo sapiens] |
| secondaryIdentifier | MCHR1_HUMAN B2RBX6 Q5R3J1 Q96S47 Q9BV08 |
| sequenceLength | 353 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:947682] MCHR1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:5624084] MCHR1 [ciliary membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q99705 MCHR1 (55810)
