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Details on Person UniProt:Q13304 GPR17
| Class:Id | ReferenceGeneProduct:55798 |
|---|---|
| _chainChangeLog | chain:1-367 added on Sat February 7 2015 |
| _displayName | UniProt:Q13304 GPR17 |
| _timestamp | 2024-11-03 20:14:37 |
| chain | chain:1-367 |
| checksum | 132FBE97BE83C60C |
| comment | FUNCTION Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.INTERACTION Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| description | recommendedName: Uracil nucleotide/cysteinyl leukotriene receptor shortName: UDP/CysLT receptor alternativeName: G-protein coupled receptor 17 alternativeName: P2Y-like receptor alternativeName: R12 |
| geneName | GPR17 |
| identifier | Q13304 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Proteomics identification Receptor Reference proteome Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | GPR17 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8998910] ENSEMBL:ENSG00000144230 GPR17 [Homo sapiens] |
| secondaryIdentifier | GPR17_HUMAN A8K9L0 B2R9X0 Q8N5S7 Q9UDZ6 Q9UE21 |
| sequenceLength | 367 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:148104] UniProt:Q13304-2 GPR17 [Homo sapiens] [ReferenceIsoform:405588] UniProt:Q13304-1 GPR17 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:416429] GPR17 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q13304 GPR17 (55798)
