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Details on Person UniProt:Q13439 GOLGA4
| Class:Id | ReferenceGeneProduct:55786 |
|---|---|
| _chainChangeLog | chain:1-2230 added on Fri February 6 2015 |
| _displayName | UniProt:Q13439 GOLGA4 |
| _timestamp | 2024-11-03 20:14:36 |
| chain | chain:1-2230 |
| checksum | 3BB733DB1EA86134 |
| comment | FUNCTION Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking (PubMed:29084197).SUBUNIT Homodimer (PubMed:14718928). Interacts with RAB6A (PubMed:10209123). Interacts with GTP-bound ARL1 and ARL3 (PubMed:11303027, PubMed:14580338, PubMed:14718928). Interacts with MACF1 (PubMed:15265687). Directly interacts with TBC1D23 (PubMed:29084197). Interacts with FAM91A1; this interaction may be mediated by TBC1D23 (PubMed:29084197).INTERACTION Additional isoforms seem to exist.DOMAIN Extended rod-like protein with coiled-coil domains.MISCELLANEOUS Antibodies against GOLGA4 are present in sera from patients with Sjoegren syndrome. Sera from patients with Sjoegren syndrome often contain antibodies that react with normal components of the Golgi complex.SEQUENCE CAUTION Extended N-terminus. |
| description | recommendedName: Golgin subfamily A member 4 alternativeName: 256 kDa golgin alternativeName: Golgin-245 alternativeName: Protein 72.1 alternativeName: Trans-Golgi p230 |
| geneName | GOLGA4 |
| identifier | Q13439 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Coiled coil Cytoplasm Glycoprotein Golgi apparatus Membrane Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | GOLGA4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8960249] ENSEMBL:ENSG00000144674 GOLGA4 [Homo sapiens] |
| secondaryIdentifier | GOGA4_HUMAN F8W8Q7 Q13270 Q13654 Q14436 Q59EW8 |
| sequenceLength | 2230 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:148096] UniProt:Q13439-3 GOLGA4 [Homo sapiens] [ReferenceIsoform:148097] UniProt:Q13439-4 GOLGA4 [Homo sapiens] [ReferenceIsoform:405615] UniProt:Q13439-1 GOLGA4 [Homo sapiens] [ReferenceIsoform:8972844] UniProt:Q13439-5 GOLGA4 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:6813884] GOLGA4 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:8960512] GOLGA4 [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:9673590] GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9673642] p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q13439 GOLGA4 (55786)
