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Details on Person KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region

Class:Id	Reaction:5577234
_displayName	KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region
_doRelease	TRUE
_timestamp	2020-02-05 16:19:44
authored	[InstanceEdit:5578924] Jassal, Bijay, 2014-06-05
catalystActivity	[CatalystActivity:5577158] A-type (transient outward) potassium channel activity of KCND tetramer:KCNIP tetramer [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:5577230] Jassal, Bijay, 2014-05-29
edited	[InstanceEdit:5578924] Jassal, Bijay, 2014-06-05
input	[SimpleEntity:29804] K+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5577065] Protein-protein interactions of KChIP proteins and Kv4.2 [LiteratureReference:5577082] Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA) [LiteratureReference:5577202] Modulation of A-type potassium channels by a family of calcium sensors [LiteratureReference:5577068] Different effects of the Ca(2+)-binding protein, KChIP1, on two Kv4 subfamily members, Kv4.1 and Kv4.2 [LiteratureReference:5577184] A fundamental role for KChIPs in determining the molecular properties and trafficking of Kv4.2 potassium channels [LiteratureReference:5577118] Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1 [LiteratureReference:5577039] Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer [LiteratureReference:5577176] Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunits
modified	[InstanceEdit:5578934] Jassal, Bijay, 2014-06-05 [InstanceEdit:6797364] Jupe, Steve, 2015-09-09 [InstanceEdit:6809172] Jassal, Bijay, 2015-11-09 [InstanceEdit:9675777] Murillo, Julieth, 2020-02-05 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region
output	[SimpleEntity:74126] K+ [extracellular region]
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6809173] Colotti, Gianni, 2015-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812354] R-HSA-5577234.3
summation	[Summation:5577197] In phase 1 of the action potential, the fast Na+ channels ar...
(hasEvent)	[Pathway:5576894] Phase 1 - inactivation of fast Na+ channels [Homo sapiens]
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No pathways have been reviewed or authored by KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (5577234)