Query author contributions in Reactome
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Details on Person UniProt:P35754 GLRX
| Class:Id | ReferenceGeneProduct:55730 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-106 added on Sat February 7 2015;initiator methionine:1 for 55730 removed on Fri Nov 03 2023;initiator methionine: for 55730 added on Fri Nov 03 2023;initiator methionine: for 55730 removed on Fri Aug 15 2025;initiator methionine:1 for 55730 added on Fri Aug 15 2025 |
| _displayName | UniProt:P35754 GLRX |
| _timestamp | 2025-08-15 22:00:42 |
| chain | initiator methionine:1 chain:2-106 |
| checksum | BB86FED55967EBE2 |
| comment | FUNCTION Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.INTERACTION Belongs to the glutaredoxin family. |
| description | recommendedName: Glutaredoxin-1 alternativeName: Thioltransferase-1 shortName: TTase-1 |
| geneName | GLRX GRX |
| identifier | P35754 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Cytoplasm Direct protein sequencing Disulfide bond Electron transport Proteomics identification Redox-active center Reference proteome Transport |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | GLRX |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962264] ENSEMBL:ENSG00000173221 GLRX [Homo sapiens] |
| secondaryIdentifier | GLRX1_HUMAN B2R4L2 Q3KQS1 Q6ICT1 |
| sequenceLength | 106 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:55729] GLRX [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:111740] 2xHC-GLRX [cytosol] [Homo sapiens] |
| (referenceSequence) | [IntraChainCrosslinkedResidue:111738] Intra-chain Crosslink via L-cystine (cross-link) at 23 and 26 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P35754 GLRX (55730)
