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Details on Person UniProt:P48546 GIPR
| Class:Id | ReferenceGeneProduct:55648 |
|---|---|
| _chainChangeLog | signal peptide:1-21 added on Sat February 7 2015;chain:22-466 added on Sat February 7 2015 |
| _displayName | UniProt:P48546 GIPR |
| _timestamp | 2023-11-03 15:02:34 |
| chain | signal peptide:1-21 chain:22-466 |
| checksum | CA5CF86BA0E32383 |
| comment | FUNCTION This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.SUBUNIT May form homodimers and heterodimers with GLP1R.INTERACTION N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER.SIMILARITY Belongs to the G-protein coupled receptor 2 family. |
| description | recommendedName: Gastric inhibitory polypeptide receptor shortName: GIP-R alternativeName: Glucose-dependent insulinotropic polypeptide receptor |
| geneName | GIPR |
| identifier | P48546 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | GIPR |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997726] ENSEMBL:ENSG00000010310 GIPR [Homo sapiens] |
| secondaryIdentifier | GIPR_HUMAN B7WP14 B7ZKQ0 Q14401 Q16400 Q52M04 Q9UPI1 |
| sequenceLength | 466 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:147928] UniProt:P48546-2 GIPR [Homo sapiens] [ReferenceIsoform:404141] UniProt:P48546-1 GIPR [Homo sapiens] [ReferenceIsoform:8964799] UniProt:P48546-3 GIPR [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:420132] GIPR [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P48546 GIPR (55648)
