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Details on Person UniProt:Q9UBI6 GNG12
| Class:Id | ReferenceGeneProduct:55426 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-69 added on Fri February 6 2015;propeptide:70-72 added on Fri February 6 2015;initiator methionine:1 for 55426 removed on Fri Nov 03 2023;initiator methionine: for 55426 added on Fri Nov 03 2023;initiator methionine: for 55426 removed on Fri Aug 15 2025;initiator methionine:1 for 55426 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q9UBI6 GNG12 |
| _timestamp | 2025-08-15 21:45:26 |
| chain | initiator methionine:1 chain:2-69 propeptide:70-72 |
| checksum | A4C489A61697FAA9 |
| comment | FUNCTION Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.SUBUNIT G proteins are composed of 3 units, alpha, beta and gamma.INTERACTION Belongs to the G protein gamma family. |
| description | recommendedName: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 |
| geneName | GNG12 |
| identifier | Q9UBI6 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Cell membrane Lipoprotein Membrane Methylation Phosphoprotein Prenylation Proteomics identification Reference proteome Transducer |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | GNG12 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9000067] ENSEMBL:ENSG00000172380 GNG12 [Homo sapiens] |
| secondaryIdentifier | GBG12_HUMAN Q69YP5 Q9BRV5 |
| sequenceLength | 72 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:164367] GNG12 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9UBI6 GNG12 (55426)
