Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Diagram of Sphingolipid metabolism

Class:Id	PathwayDiagram:554229
_displayName	Diagram of Sphingolipid metabolism
_timestamp	2025-06-23 12:06:07
created	[InstanceEdit:554230] D'Eustachio, P, 2010-03-21
height	1478
modified	[InstanceEdit:1679954] Wu, G, 2011-10-20 [InstanceEdit:1807966] Jupe, S, 2011-10-24 [InstanceEdit:1861756] Jassal, B, 2011-10-31 [InstanceEdit:1869594] Jassal, B, 2011-10-31 [InstanceEdit:2028233] Matthews, L, 2011-12-23 [InstanceEdit:2110964] D'Eustachio, P, 2012-02-13 [InstanceEdit:2248890] Jassal, B, 2012-05-15 [InstanceEdit:2261282] D'Eustachio, P, 2012-05-19 [InstanceEdit:2603292] D'Eustachio, P, 2012-11-19 [InstanceEdit:4088016] Matthews, L, 2013-08-08 [InstanceEdit:4127418] Gillespie, ME, 2013-08-14 [InstanceEdit:5340614] Jassal, B, 2014-03-20 [InstanceEdit:5380261] D'Eustachio, Peter, 2014-04-28 [InstanceEdit:5545467] Matthews, Lisa, 2014-05-21 [InstanceEdit:6782156] Jassal, Bijay, 2015-06-05 [InstanceEdit:6782174] Jassal, Bijay, 2015-06-05 [InstanceEdit:6782833] Jassal, Bijay, 2015-06-09 [InstanceEdit:6793922] Jassal, Bijay, 2015-09-04 [InstanceEdit:6808482] D'Eustachio, Peter, 2015-11-04 [InstanceEdit:6811642] D'Eustachio, Peter, 2015-11-19 [InstanceEdit:8847451] D'Eustachio, Peter, 2015-11-30 [InstanceEdit:8855180] Wu, G, 2016-02-02 [InstanceEdit:8863752] Jassal, Bijay, 2016-03-10 [InstanceEdit:8863753] Jassal, Bijay, 2016-03-10 [InstanceEdit:8863780] Jassal, Bijay, 2016-03-10 [InstanceEdit:8865588] Jupe, Steve, 2016-03-23 [InstanceEdit:8877167] Jassal, Bijay, 2016-06-21 [InstanceEdit:8934422] Jassal, Bijay, 2016-08-09 [InstanceEdit:8959601] Jassal, Bijay, 2017-01-27 [InstanceEdit:9032941] D'Eustachio, Peter, 2017-12-19 [InstanceEdit:9032942] D'Eustachio, Peter, 2017-12-19 [InstanceEdit:9604440] Jassal, Bijay, 2018-04-03 [InstanceEdit:9605722] Jassal, Bijay, 2018-04-17 [InstanceEdit:9632235] Jassal, Bijay, 2018-12-17 [InstanceEdit:9638148] Jassal, Bijay, 2019-02-26 [InstanceEdit:9645116] Wu, G, 2019-05-03 [InstanceEdit:9695886] Jassal, Bijay, 2020-07-16 [InstanceEdit:9695897] Jassal, Bijay, 2020-07-16 [InstanceEdit:9695955] Jassal, Bijay, 2020-07-16 [InstanceEdit:9700880] Jassal, Bijay, 2020-09-21 [InstanceEdit:9753296] Jassal, Bijay, 2021-09-06 [InstanceEdit:9840611] Stephan, Ralf, 2023-07-20 [InstanceEdit:9840612] Stephan, Ralf, 2023-07-20 [InstanceEdit:9840623] Stephan, Ralf, 2023-07-21 [InstanceEdit:9840647] Stephan, Ralf, 2023-07-22 [InstanceEdit:9840697] Stephan, Ralf, 2023-07-24 [InstanceEdit:9840715] Stephan, Ralf, 2023-07-25 [InstanceEdit:9840730] Stephan, Ralf, 2023-07-25 [InstanceEdit:9840794] Stephan, Ralf, 2023-07-27 [InstanceEdit:9840815] Stephan, Ralf, 2023-07-28 [InstanceEdit:9840838] Stephan, Ralf, 2023-07-29 [InstanceEdit:9840844] Stephan, Ralf, 2023-07-30 [InstanceEdit:9840856] Stephan, Ralf, 2023-07-30 [InstanceEdit:9840892] Stephan, Ralf, 2023-08-01 [InstanceEdit:9840940] Stephan, Ralf, 2023-08-02 [InstanceEdit:9840953] Stephan, Ralf, 2023-08-02 [InstanceEdit:9840963] Stephan, Ralf, 2023-08-03 [InstanceEdit:9840967] Stephan, Ralf, 2023-08-03 [InstanceEdit:9840986] Stephan, Ralf, 2023-08-04 [InstanceEdit:9840993] Stephan, Ralf, 2023-08-04 [InstanceEdit:9840997] Stephan, Ralf, 2023-08-07 [InstanceEdit:9841141] Stephan, Ralf, 2023-08-09 [InstanceEdit:9841164] Stephan, Ralf, 2023-08-10 [InstanceEdit:9841169] Stephan, Ralf, 2023-08-11 [InstanceEdit:9841226] Stephan, Ralf, 2023-08-11 [InstanceEdit:9841785] Stephan, Ralf, 2023-08-12 [InstanceEdit:9841786] Stephan, Ralf, 2023-08-12 [InstanceEdit:9841797] Stephan, Ralf, 2023-08-14 [InstanceEdit:9841884] Stephan, Ralf, 2023-08-15 [InstanceEdit:9841887] Stephan, Ralf, 2023-08-15 [InstanceEdit:9841948] Stephan, Ralf, 2023-08-16 [InstanceEdit:9842007] Matthews, Lisa, 2023-08-16 [InstanceEdit:9842060] Stephan, Ralf, 2023-08-17 [InstanceEdit:9842099] Matthews, Lisa, 2023-08-17 [InstanceEdit:9842100] Matthews, Lisa, 2023-08-17 [InstanceEdit:9842114] Stephan, Ralf, 2023-08-18 [InstanceEdit:9842139] Stephan, Ralf, 2023-08-21 [InstanceEdit:9842142] Stephan, Ralf, 2023-08-21 [InstanceEdit:9842382] Stephan, Ralf, 2023-08-27 [InstanceEdit:9842410] Stephan, Ralf, 2023-08-27 [InstanceEdit:9842411] Stephan, Ralf, 2023-08-27 [InstanceEdit:9842696] Stephan, Ralf, 2023-08-28 [InstanceEdit:9842826] Matthews, Lisa, 2023-08-28 [InstanceEdit:9843001] Stephan, Ralf, 2023-08-30 [InstanceEdit:9843104] Stephan, Ralf, 2023-08-31 [InstanceEdit:9843179] Stephan, Ralf, 2023-09-01 [InstanceEdit:9843203] Stephan, Ralf, 2023-09-04 [InstanceEdit:9843207] Stephan, Ralf, 2023-09-04 [InstanceEdit:9843209] Stephan, Ralf, 2023-09-05 [InstanceEdit:9843248] Stephan, Ralf, 2023-09-06 [InstanceEdit:9843704] Stephan, Ralf, 2023-09-09 [InstanceEdit:9843718] Stephan, Ralf, 2023-09-09 [InstanceEdit:9843723] Stephan, Ralf, 2023-09-10 [InstanceEdit:9843844] Stephan, Ralf, 2023-09-12 [InstanceEdit:9844150] Stephan, Ralf, 2023-09-13 [InstanceEdit:9844176] Stephan, Ralf, 2023-09-14 [InstanceEdit:9844332] Stephan, Ralf, 2023-09-15 [InstanceEdit:9844337] Stephan, Ralf, 2023-09-15 [InstanceEdit:9844398] Stephan, Ralf, 2023-09-16 [InstanceEdit:9844577] Stephan, Ralf, 2023-09-20 [InstanceEdit:9844586] Stephan, Ralf, 2023-09-21 [InstanceEdit:9844591] Stephan, Ralf, 2023-09-21 [InstanceEdit:9844761] Stephan, Ralf, 2023-09-22 [InstanceEdit:9844891] Stephan, Ralf, 2023-09-23 [InstanceEdit:9844892] Stephan, Ralf, 2023-09-23 [InstanceEdit:9844958] Stephan, Ralf, 2023-09-25 [InstanceEdit:9844976] Stephan, Ralf, 2023-09-25 [InstanceEdit:9844978] Stephan, Ralf, 2023-09-25 [InstanceEdit:9845048] Stephan, Ralf, 2023-09-26 [InstanceEdit:9845283] Stephan, Ralf, 2023-10-01 [InstanceEdit:9845490] Stephan, Ralf, 2023-10-03 [InstanceEdit:9845496] Stephan, Ralf, 2023-10-03 [InstanceEdit:9845506] Stephan, Ralf, 2023-10-03 [InstanceEdit:9845508] Stephan, Ralf, 2023-10-04 [InstanceEdit:9845512] Stephan, Ralf, 2023-10-04 [InstanceEdit:9845553] Stephan, Ralf, 2023-10-05 [InstanceEdit:9845577] Stephan, Ralf, 2023-10-05 [InstanceEdit:9845595] Stephan, Ralf, 2023-10-05 [InstanceEdit:9845613] Stephan, Ralf, 2023-10-06 [InstanceEdit:9845616] Stephan, Ralf, 2023-10-06 [InstanceEdit:9845639] Stephan, Ralf, 2023-10-07 [InstanceEdit:9845642] Stephan, Ralf, 2023-10-07 [InstanceEdit:9845645] Stephan, Ralf, 2023-10-07 [InstanceEdit:9845648] Stephan, Ralf, 2023-10-07 [InstanceEdit:9846167] Stephan, Ralf, 2023-10-09 [InstanceEdit:9846296] Stephan, Ralf, 2023-10-10 [InstanceEdit:9846304] Stephan, Ralf, 2023-10-10 [InstanceEdit:9846342] Stephan, Ralf, 2023-10-10 [InstanceEdit:9846494] Stephan, Ralf, 2023-10-11 [InstanceEdit:9846513] Stephan, Ralf, 2023-10-11 [InstanceEdit:9850756] Stephan, Ralf, 2023-10-12 [InstanceEdit:9851290] Stephan, Ralf, 2023-10-17 [InstanceEdit:9851293] Stephan, Ralf, 2023-10-20 [InstanceEdit:9851352] Stephan, Ralf, 2023-10-24 [InstanceEdit:9851357] Stephan, Ralf, 2023-10-24 [InstanceEdit:9851457] Stephan, Ralf, 2023-10-26 [InstanceEdit:9851495] Stephan, Ralf, 2023-10-26 [InstanceEdit:9852984] Stephan, Ralf, 2023-11-09 [InstanceEdit:9859510] Stephan, Ralf, 2024-01-20 [InstanceEdit:9863732] Matthews, Lisa, 2024-03-05 [InstanceEdit:9863942] Matthews, Lisa, 2024-03-06 [InstanceEdit:9910859] D'Eustachio, Peter, 2024-05-21 [InstanceEdit:9918576] Matthews, Lisa, 2024-08-17 [InstanceEdit:9953023] Stephan, Ralf, 2025-05-28 [InstanceEdit:9956913] D'Eustachio, Peter, 2025-06-16 [InstanceEdit:9958571] D'Eustachio, Peter, 2025-06-23
representedPathway	[Pathway:428157] Sphingolipid metabolism [Homo sapiens]
storedATXML	<?xml version="1.0" encoding="UTF-8"?> <Process nextId="27441" reactomeDiagramId="554229"> <Properties> <displayName>Diagram of Sphingolipid metabolism</displayName> </Properties> <Nodes> <org.gk.render.RenderableCompartment id="1" reactomeId="70101" position="1513 711" bounds="122 74 2782 1275" textPosition="630 1153" bgColor="250 240 240" lineColor="255 153 102" insets="130 82 2757 1262"> <Properties> <displayName>cytosol</displayName> </Properties> <Components> <Component id="4" /> <Component id="5" /> <Component id="17" /> <Component id="24" /> <Component id="28" /> <Component id="36" /> <Component id="63" /> <Component id="69" /> <Component id="70" /> <Component id="74" /> <Component id="79" /> <Component id="85" /> <Component id="111" /> <Component id="115" /> <Component id="113" /> <Component id="114" /> <Component id="112" /> <Component id="118" /> <Component id="120" /> <Component id="121" /> <Component id="117" /> <Component id="126" /> <Component id="290" /> <Component id="292" /> <Component id="294" /> <Component id="295" /> <Component id="291" /> <Component id="297" /> <Component id="298" /> <Component id="299" /> <Component id="300" /> <Component id="301" /> <Component id="29" /> <Component id="141" /> <Component id="1238" /> <Component id="7" /> <Component id="9" /> <Component id="18" /> <Component id="19" /> <Component id="20" /> <Component id="30" /> <Component id="1267" /> <Component id="51" /> <Component id="66" /> <Component id="43" /> <Component id="2375" /> <Component id="2382" /> <Component id="2383" /> <Component id="2384" /> <Component id="2388" /> <Component id="2386" /> <Component id="2385" /> <Component id="2389" /> <Component id="2391" /> <Component id="2393" /> <Component id="2677" /> <Component id="2867" /> <Component id="2938" /> <Component id="2940" /> <Component id="2941" /> <Component id="2942" /> <Component id="2950" /> <Component id="2948" /> <Component id="2954" /> <Component id="2956" /> <Component id="3111" /> <Component id="2381" /> <Component id="2390" /> <Component id="3294" /> <Component id="3442" /> <Component id="3760" /> <Component id="3776" /> <Component id="3779" /> <Component id="3877" /> <Component id="3878" /> <Component id="3879" /> <Component id="3901" /> <Component id="3898" /> <Component id="3897" /> <Component id="3906" /> <Component id="25968" /> <Component id="2857" /> <Component id="26031" /> <Component id="26206" /> <Component id="26216" /> <Component id="26219" /> <Component id="26303" /> <Component id="50" /> <Component id="26299" /> <Component id="26232" /> <Component id="26307" /> <Component id="26333" /> <Component id="26334" /> <Component id="26337" /> <Component id="26335" /> <Component id="26336" /> <Component id="26518" /> <Component id="26348" /> <Component id="26350" /> <Component id="26516" /> <Component id="26527" /> <Component id="26531" /> <Component id="26533" /> <Component id="26540" /> <Component id="26539" /> <Component id="26541" /> <Component id="26542" /> <Component id="26543" /> <Component id="26544" /> <Component id="26545" /> <Component id="26547" /> <Component id="26550" /> <Component id="26589" /> <Component id="26535" /> <Component id="25988" /> <Component id="40" /> <Component id="26596" /> <Component id="26598" /> <Component id="26599" /> <Component id="26597" /> <Component id="26594" /> <Component id="135" /> <Component id="136" /> <Component id="137" /> <Component id="139" /> <Component id="371" /> <Component id="447" /> <Component id="456" /> <Component id="1255" /> <Component id="1256" /> <Component id="1257" /> <Component id="1258" /> <Component id="1309" /> <Component id="2532" /> <Component id="2868" /> <Component id="26367" /> <Component id="26517" /> <Component id="134" /> <Component id="1254" /> <Component id="1307" /> <Component id="26593" /> <Component id="26580" /> <Component id="27231" /> <Component id="27230" /> <Component id="27232" /> <Component id="26582" /> <Component id="27240" /> <Component id="27244" /> <Component id="78" /> <Component id="27247" /> <Component id="27248" /> <Component id="27249" /> <Component id="27251" /> <Component id="26612" /> <Component id="27256" /> <Component id="2946" /> <Component id="27258" /> <Component id="2952" /> <Component id="27262" /> <Component id="27266" /> <Component id="27280" /> <Component id="103" /> <Component id="27311" /> <Component id="27407" /> <Component id="27411" /> <Component id="27274" /> <Component id="27418" /> <Component id="27419" /> <Component id="27420" /> <Component id="27156" /> <Component id="27335" /> <Component id="27176" /> <Component id="27421" /> <Component id="27428" /> <Component id="3609" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="5" reactomeId="200736" position="597 110" bounds="573 95 48 31" textPosition="577 99"> <Properties> <displayName>L-Ser</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="7" reactomeId="113528" position="549 202" bounds="528 187 42 31" textPosition="532 191"> <Properties> <displayName>CO2</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9" reactomeId="76194" position="537 243" bounds="506 228 62 31" textPosition="510 232" /> <org.gk.render.RenderableEntitySet id="10" reactomeId="428174" position="741 215" bounds="686 204 110 23" textPosition="686 204" bgColor="204 255 255"> <Properties> <displayName>SPTLC complexes</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="18" reactomeId="29364" position="544 281" bounds="515 266 59 31" textPosition="519 270"> <Properties> <displayName>NADPH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="19" reactomeId="70106" position="632 250" bounds="614 235 36 31" textPosition="618 239" /> <org.gk.render.RenderableChemical id="20" reactomeId="29366" position="549 340" bounds="519 325 60 31" textPosition="523 329"> <Properties> <displayName>NADP+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="22" reactomeId="428134" position="721 300" bounds="701 289 40 23" textPosition="701 289"> <Properties> <displayName>KDSR</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="26" reactomeId="428126" position="730 515" bounds="705 500 50 31" textPosition="709 504"> <Properties> <displayName>DHCE</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="27" reactomeId="428153" position="719 430" bounds="657 419 125 23" textPosition="657 419"> <Properties> <displayName>Ceramide synthases</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="28" reactomeId="76194" position="576 463" bounds="545 448 62 31" textPosition="549 452"> <Properties> <displayName>CoA-SH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="30" reactomeId="29368" position="584 542" bounds="567 527 34 31" textPosition="571 531" /> <org.gk.render.RenderableProtein id="33" reactomeId="428233" position="735 560" bounds="711 549 48 23" textPosition="711 549"> <Properties> <displayName>DEGS2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="36" reactomeId="70106" position="661 507" bounds="643 492 36 31" textPosition="647 496" /> <org.gk.render.RenderableChemical id="40" reactomeId="428237" position="586 696" bounds="528 681 117 31" textPosition="532 685"> <Properties> <displayName>phytosphingosine</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="46" reactomeId="428256" position="986 600" bounds="962 585 48 31" textPosition="966 589"> <Properties> <displayName>CERA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="48" reactomeId="428201" position="981 514" bounds="957 503 48 23" textPosition="957 503"> <Properties> <displayName>DEGS1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="50" reactomeId="70106" position="1136 587" bounds="1118 572 36 31" textPosition="1122 576" /> <org.gk.render.RenderableChemical id="51" reactomeId="29368" position="1217 581" bounds="1200 566 34 31" textPosition="1204 570" /> <org.gk.render.RenderableProtein id="55" reactomeId="428221" position="992 667" bounds="968 656 48 23" textPosition="968 656"> <Properties> <displayName>ACER1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="66" reactomeId="428203" position="1425 739" bounds="1391 724 69 31" textPosition="1395 728" /> <org.gk.render.RenderableChemical id="69" reactomeId="428686" position="1328 232" bounds="1305 217 47 31" textPosition="1309 221"> <Properties> <displayName>PETA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="70" reactomeId="428663" position="1167 170" bounds="1143 155 48 31" textPosition="1147 159" /> <org.gk.render.RenderableProtein id="71" reactomeId="428661" position="985 290" bounds="945 279 80 23" textPosition="945 279"> <Properties> <displayName>PXLP-SGPL1</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.30357142857142855" relativeY="0.0" label="PP" trackId="0" reactomeId="554224" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="74" reactomeId="428671" position="1468 227" bounds="1435 212 66 31" textPosition="1439 216"> <Properties> <displayName>HD2NAL</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="78" reactomeId="29372" position="1009 804" bounds="996 789 27 31" textPosition="1000 793" /> <org.gk.render.RenderableEntitySet id="79" reactomeId="428110" position="1605 1335" bounds="1571 1324 68 23" textPosition="1571 1324"> <Properties> <displayName>PLPP1,2,3</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="81" reactomeId="109276" position="1570 1424" bounds="1549 1409 43 31" textPosition="1553 1413" /> <org.gk.render.RenderableChemical id="82" reactomeId="419305" position="1518 1389" bounds="1484 1374 69 31" textPosition="1488 1378"> <Properties> <displayName>C18-S1P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="83" reactomeId="109277" position="1673 1421" bounds="1660 1406 27 31" textPosition="1664 1410"> <Properties> <displayName>Pi</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="85" reactomeId="76106" position="1521 1342" bounds="1499 1331 44 23" textPosition="1499 1331"> <Properties> <displayName>PLPP1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="90" reactomeId="428667" position="987 838" bounds="968 827 38 23" textPosition="968 827"> <Properties> <displayName>SGPP</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="99" reactomeId="429672" position="721 1003" bounds="667 985 109 37" textPosition="667 986" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>CERT1-2:PPM1L:VAPA/B dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="102" reactomeId="428270" position="504 987" bounds="480 972 48 31" textPosition="484 976" /> <org.gk.render.RenderableProtein id="103" reactomeId="429725" position="630 906" bounds="611 895 38 23" textPosition="611 895"> <Properties> <displayName>OSBP</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="107" reactomeId="428239" position="499 919" bounds="475 908 48 23" textPosition="475 908"> <Properties> <displayName>ACER2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="110" reactomeId="429703" position="987 1258" bounds="938 1240 99 37" textPosition="938 1241" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PPM1L:VAPA/B dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="111" reactomeId="429712" position="1168 987" bounds="1137 976 63 23" textPosition="1137 976"> <Properties> <displayName>CERT1-2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="113" reactomeId="113592" position="1251 997" bounds="1231 982 40 31" textPosition="1235 986" /> <org.gk.render.RenderableProtein id="114" reactomeId="429704" position="1147 1096" bounds="1090 1085 115 23" textPosition="1090 1085"> <Properties> <displayName>p-S132-CERT1-2</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.12403100775193798" relativeY="0.0" label="P" description="Ser" trackId="0" reactomeId="429666" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="115" reactomeId="29370" position="1257 1091" bounds="1237 1076 41 31" textPosition="1241 1080" /> <org.gk.render.RenderableChemical id="118" reactomeId="113592" position="1101 1141" bounds="1081 1126 40 31" textPosition="1085 1130" /> <org.gk.render.RenderableProtein id="120" reactomeId="429695" position="1149 1272" bounds="1099 1250 101 44" textPosition="1108 1254"> <Properties> <displayName>p-S,S132,T-CERT1-2</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.16494845360824742" relativeY="0.0" label="P" description="Ser" trackId="0" reactomeId="429666" /> <org.gk.render.RenderableFeature relativeX="0.32989690721649484" relativeY="0.0" label="P" description="Ser" trackId="0" reactomeId="429667" /> <org.gk.render.RenderableFeature relativeX="0.4948453608247423" relativeY="0.0" label="P" description="Thr" trackId="0" reactomeId="429682" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="121" reactomeId="429696" position="1231 1177" bounds="1199 1166 65 23" textPosition="1199 1166"> <Properties> <displayName>CSNK1G2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="126" reactomeId="29372" position="1039 954" bounds="1026 939 27 31" textPosition="1030 943" /> <org.gk.render.RenderableChemical id="129" reactomeId="429785" position="281 478" bounds="265 463 32 31" textPosition="269 467"> <Properties> <displayName>PC</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="131" reactomeId="429789" position="275 604" bounds="251 589 49 31" textPosition="255 593"> <Properties> <displayName>SPHM</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="132" reactomeId="429782" position="282 518" bounds="258 507 48 23" textPosition="258 507"> <Properties> <displayName>SGMS1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="135" reactomeId="429807" position="122 556" bounds="98 541 48 31" textPosition="102 545" /> <org.gk.render.RenderableChemical id="136" reactomeId="429802" position="130 605" bounds="114 590 32 31" textPosition="118 594" /> <org.gk.render.RenderableChemical id="137" reactomeId="429776" position="117 430" bounds="73 415 89 31" textPosition="77 419" /> <org.gk.render.RenderableProtein id="139" reactomeId="429775" position="130 513" bounds="77 502 106 23" textPosition="77 502"> <Properties> <displayName>2xPalmC-SGMS2</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.2361111111111111" relativeY="0.0" label="Pa" trackId="0" reactomeId="429801" /> <org.gk.render.RenderableFeature relativeX="0.4861111111111111" relativeY="0.0" label="Pa" trackId="0" reactomeId="429783" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableCompartment id="141" reactomeId="161320" position="2375 774" bounds="1880 232 991 1085" textPosition="2483 278" bgColor="250 240 240" lineColor="255 153 102" insets="1893 242 961 1057"> <Properties> <displayName>lysosomal lumen</displayName> </Properties> <Components> <Component id="143" /> <Component id="147" /> <Component id="151" /> <Component id="152" /> <Component id="153" /> <Component id="156" /> <Component id="275" /> <Component id="276" /> <Component id="280" /> <Component id="282" /> <Component id="283" /> <Component id="284" /> <Component id="285" /> <Component id="288" /> <Component id="346" /> <Component id="352" /> <Component id="355" /> <Component id="356" /> <Component id="357" /> <Component id="358" /> <Component id="360" /> <Component id="359" /> <Component id="361" /> <Component id="363" /> <Component id="366" /> <Component id="367" /> <Component id="397" /> <Component id="442" /> <Component id="438" /> <Component id="439" /> <Component id="441" /> <Component id="2676" /> <Component id="2863" /> <Component id="2866" /> <Component id="2860" /> <Component id="3504" /> <Component id="3505" /> <Component id="3902" /> <Component id="3904" /> <Component id="3970" /> <Component id="3971" /> <Component id="3972" /> <Component id="3968" /> <Component id="3969" /> <Component id="3974" /> <Component id="3975" /> <Component id="4040" /> <Component id="4036" /> <Component id="4825" /> <Component id="4826" /> <Component id="4828" /> <Component id="4833" /> <Component id="4827" /> <Component id="5015" /> <Component id="5017" /> <Component id="5321" /> <Component id="5328" /> <Component id="6653" /> <Component id="6654" /> <Component id="4829" /> <Component id="6656" /> <Component id="6718" /> <Component id="6962" /> <Component id="6961" /> <Component id="6963" /> <Component id="7686" /> <Component id="7687" /> <Component id="7688" /> <Component id="7750" /> <Component id="15734" /> <Component id="16278" /> <Component id="16279" /> <Component id="16280" /> <Component id="3973" /> <Component id="16586" /> <Component id="16588" /> <Component id="25710" /> <Component id="25715" /> <Component id="25712" /> <Component id="25714" /> <Component id="25720" /> <Component id="25743" /> <Component id="25739" /> <Component id="25745" /> <Component id="25741" /> <Component id="25740" /> <Component id="25748" /> <Component id="25754" /> <Component id="25756" /> <Component id="398" /> <Component id="394" /> <Component id="25764" /> <Component id="25762" /> <Component id="25767" /> <Component id="25761" /> <Component id="25763" /> <Component id="25769" /> <Component id="25775" /> <Component id="25781" /> <Component id="25780" /> <Component id="25782" /> <Component id="25951" /> <Component id="25952" /> <Component id="25955" /> <Component id="25958" /> <Component id="25960" /> <Component id="25962" /> <Component id="26036" /> <Component id="26039" /> <Component id="27317" /> <Component id="26037" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="147" reactomeId="1605637" position="2089 313" bounds="2071 298 36 31" textPosition="2075 302" /> <org.gk.render.RenderableProtein id="151" reactomeId="1605614" position="2605 348" bounds="2556 337 99 23" textPosition="2556 337" /> <org.gk.render.RenderableComplex id="152" reactomeId="1605600" position="1945 272" bounds="1908 261 75 23" textPosition="1908 262" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GM2A:GM2</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="156" reactomeId="1605658" position="1936 951" bounds="1907 936 59 31" textPosition="1911 940"> <Properties> <displayName>GalNAc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="276" reactomeId="1605715" position="2258 447" bounds="2237 432 43 31" textPosition="2241 436" /> <org.gk.render.RenderableChemical id="282" reactomeId="1605601" position="2412 684" bounds="2384 669 56 31" textPosition="2388 673"> <Properties> <displayName>LacCer</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="283" reactomeId="1605744" position="1933 824" bounds="1909 808 49 32" textPosition="1912 804" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GLA dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="284" reactomeId="1605637" position="1949 746" bounds="1931 731 36 31" textPosition="1935 735" /> <org.gk.render.RenderableEntitySet id="288" reactomeId="1605688" position="1942 595" bounds="1916 584 53 23" textPosition="1916 584"> <Properties> <displayName>NEU1,4</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="291" reactomeId="29356" position="1712 1049" bounds="1691 1034 43 31" textPosition="1695 1038" /> <org.gk.render.RenderableChemical id="292" reactomeId="1605590" position="1790 1048" bounds="1768 1033 44 31" textPosition="1772 1037" /> <org.gk.render.RenderableChemical id="294" reactomeId="1605647" position="1807 1170" bounds="1779 1155 56 31" textPosition="1783 1159" /> <org.gk.render.RenderableProtein id="295" reactomeId="1605759" position="1811 1117" bounds="1791 1106 41 23" textPosition="1791 1106"> <Properties> <displayName>NEU2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="298" reactomeId="1605649" position="1811 1338" bounds="1789 1323 44 31" textPosition="1793 1327"> <Properties> <displayName>GM3</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="299" reactomeId="29356" position="1810 1240" bounds="1789 1225 43 31" textPosition="1793 1229" /> <org.gk.render.RenderableChemical id="300" reactomeId="1605618" position="1689 1337" bounds="1661 1322 56 31" textPosition="1665 1326" /> <org.gk.render.RenderableProtein id="301" reactomeId="1605644" position="1746 1327" bounds="1726 1316 41 23" textPosition="1726 1316"> <Properties> <displayName>NEU3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="355" reactomeId="1605745" position="2320 1039" bounds="2303 1024 35 31" textPosition="2307 1028" /> <org.gk.render.RenderableChemical id="356" reactomeId="1605673" position="2405 1026" bounds="2381 1011 48 31" textPosition="2385 1015" /> <org.gk.render.RenderableComplex id="357" reactomeId="1605675" position="2858 942" bounds="2821 931 74 23" textPosition="2821 932" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GBA1:SAPC</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="359" reactomeId="1606573" position="2206 1002" bounds="2178 987 56 31" textPosition="2182 991" /> <org.gk.render.RenderableChemical id="360" reactomeId="1605715" position="2237 960" bounds="2216 945 43 31" textPosition="2220 949" /> <org.gk.render.RenderableProtein id="361" reactomeId="1606575" position="2282 1068" bounds="2262 1057 40 23" textPosition="2262 1057"> <Properties> <displayName>GALC</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="366" reactomeId="1606588" position="2404 1159" bounds="2385 1144 39 31" textPosition="2389 1148" /> <org.gk.render.RenderableComplex id="367" reactomeId="1606584" position="2342 1094" bounds="2318 1083 48 23" textPosition="2318 1084" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ASAH1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="371" reactomeId="1606609" position="129 240" bounds="110 225 39 31" textPosition="114 229"> <Properties> <displayName>SPG</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="397" reactomeId="1606845" position="2160 867" bounds="2129 852 63 31" textPosition="2133 856"> <Properties> <displayName>SO4(2-)</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="398" reactomeId="1606814" position="2134 821" bounds="2078 810 113 23" textPosition="2078 811" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="439" reactomeId="1605713" position="2559 839" bounds="2515 824 89 31" textPosition="2519 828"> <Properties> <displayName>SPHM d18:1</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="441" reactomeId="1605750" position="2547 978" bounds="2524 963 46 31" textPosition="2528 967" /> <org.gk.render.RenderableProtein id="442" reactomeId="1605710" position="2621 906" bounds="2597 895 49 23" textPosition="2597 895"> <Properties> <displayName>SMPD1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="447" reactomeId="1606266" position="119 695" bounds="69 684 100 23" textPosition="69 685" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>SMPD2,3:Mg2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="456" reactomeId="1610735" position="130 651" bounds="107 636 46 31" textPosition="111 640" /> <org.gk.render.RenderableChemical id="476" reactomeId="1606283" position="721 838" bounds="677 823 89 31" textPosition="681 827" /> <org.gk.render.RenderableChemical id="477" reactomeId="113519" position="838 817" bounds="817 802 43 31" textPosition="821 806" /> <org.gk.render.RenderableChemical id="478" reactomeId="1606280" position="722 747" bounds="699 732 46 31" textPosition="703 736"> <Properties> <displayName>ChoP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="479" reactomeId="1606289" position="720 789" bounds="676 778 88 23" textPosition="676 779" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>SMPD4:Mg2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableCompartment id="1238" reactomeId="17963" position="387 731" bounds="271 147 233 1169" textPosition="407 1266" bgColor="250 240 240" lineColor="255 153 102" insets="279 155 219 1150"> <Properties> <displayName>Golgi lumen</displayName> </Properties> <Components> <Component id="102" /> <Component id="107" /> <Component id="128" /> <Component id="132" /> <Component id="129" /> <Component id="131" /> <Component id="1241" /> <Component id="1242" /> <Component id="1243" /> <Component id="1245" /> <Component id="2102" /> <Component id="3118" /> <Component id="3119" /> <Component id="3120" /> <Component id="3121" /> <Component id="3122" /> <Component id="3429" /> <Component id="3432" /> <Component id="3431" /> <Component id="3430" /> <Component id="3434" /> <Component id="26357" /> <Component id="26650" /> <Component id="26656" /> <Component id="26653" /> <Component id="26652" /> <Component id="26657" /> <Component id="26710" /> <Component id="26711" /> <Component id="26712" /> <Component id="26718" /> <Component id="26714" /> <Component id="26715" /> <Component id="26716" /> <Component id="26972" /> <Component id="26991" /> <Component id="26995" /> <Component id="26994" /> <Component id="26993" /> <Component id="26997" /> <Component id="26999" /> <Component id="27138" /> <Component id="27142" /> <Component id="27162" /> <Component id="27165" /> <Component id="27177" /> <Component id="27179" /> <Component id="27181" /> <Component id="27183" /> <Component id="27174" /> <Component id="27173" /> <Component id="27190" /> <Component id="27191" /> <Component id="27192" /> <Component id="27195" /> <Component id="27197" /> <Component id="27199" /> <Component id="27201" /> <Component id="27222" /> <Component id="27223" /> <Component id="27225" /> <Component id="27227" /> <Component id="27324" /> <Component id="27325" /> <Component id="27326" /> <Component id="27323" /> <Component id="27333" /> <Component id="27334" /> <Component id="27336" /> <Component id="27337" /> <Component id="27338" /> <Component id="27347" /> <Component id="27348" /> <Component id="27350" /> <Component id="27352" /> <Component id="27354" /> <Component id="27359" /> <Component id="27361" /> <Component id="27362" /> <Component id="27367" /> <Component id="27369" /> <Component id="27370" /> <Component id="27371" /> <Component id="27224" /> <Component id="27365" /> <Component id="27417" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="1242" reactomeId="744227" position="418 1021" bounds="385 1006 66 31" textPosition="389 1010"> <Properties> <displayName>UDP-Glc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1243" reactomeId="205687" position="398 979" bounds="378 964 41 31" textPosition="382 968" /> <org.gk.render.RenderableProtein id="1245" reactomeId="1631585" position="503 1062" bounds="482 1051 43 23" textPosition="482 1051"> <Properties> <displayName>UGCG</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1255" reactomeId="113592" position="213 207" bounds="193 192 40 31" textPosition="197 196" /> <org.gk.render.RenderableChemical id="1256" reactomeId="29370" position="217 110" bounds="197 95 41 31" textPosition="201 99" /> <org.gk.render.RenderableChemical id="1257" reactomeId="1638840" position="127 95" bounds="107 80 40 31" textPosition="111 84"> <Properties> <displayName>C1P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="1258" reactomeId="1631584" position="124 163" bounds="104 152 40 23" textPosition="104 152"> <Properties> <displayName>CERK</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1267" reactomeId="29356" position="210 403" bounds="189 388 43 31" textPosition="193 392" /> <org.gk.render.RenderableProtein id="1309" reactomeId="1631583" position="131 745" bounds="108 734 47 23" textPosition="108 734"> <Properties> <displayName>ENPP7</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2102" reactomeId="1660674" position="498 1249" bounds="471 1234 55 31" textPosition="475 1238"> <Properties> <displayName>GlcCer</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="2371" reactomeId="1614355" position="837 1269" bounds="781 1258 113 23" textPosition="781 1259" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>active ARSA:Ca2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableCompartment id="2381" reactomeId="17957" position="852 725" bounds="716 137 273 1176" textPosition="739 355" bgColor="250 240 240" lineColor="255 153 102" insets="726 148 255 1155"> <Properties> <displayName>endoplasmic reticulum lumen</displayName> </Properties> <Components> <Component id="99" /> <Component id="110" /> <Component id="90" /> <Component id="55" /> <Component id="46" /> <Component id="48" /> <Component id="476" /> <Component id="477" /> <Component id="475" /> <Component id="478" /> <Component id="71" /> <Component id="10" /> <Component id="22" /> <Component id="27" /> <Component id="26" /> <Component id="479" /> <Component id="33" /> <Component id="2750" /> <Component id="2754" /> <Component id="2755" /> <Component id="2756" /> <Component id="2751" /> <Component id="2752" /> <Component id="2753" /> <Component id="2371" /> <Component id="2858" /> <Component id="2859" /> <Component id="3096" /> <Component id="3117" /> <Component id="3438" /> <Component id="3435" /> <Component id="3440" /> <Component id="3445" /> <Component id="3503" /> <Component id="3279" /> <Component id="26033" /> <Component id="26202" /> <Component id="26203" /> <Component id="26298" /> <Component id="26344" /> <Component id="26346" /> <Component id="26513" /> <Component id="26509" /> <Component id="26514" /> <Component id="26578" /> <Component id="26574" /> <Component id="3107" /> <Component id="3104" /> <Component id="26640" /> <Component id="26642" /> <Component id="26644" /> <Component id="26645" /> <Component id="27283" /> <Component id="27307" /> <Component id="27315" /> <Component id="27427" /> <Component id="27438" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="2383" reactomeId="1861782" position="1614 73" bounds="1587 58 55 31" textPosition="1591 62" /> <org.gk.render.RenderableChemical id="2384" reactomeId="29356" position="1616 138" bounds="1595 123 43 31" textPosition="1599 127" /> <org.gk.render.RenderableChemical id="2385" reactomeId="70113" position="1786 121" bounds="1769 106 35 31" textPosition="1773 110"> <Properties> <displayName>Glc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="2386" reactomeId="1861791" position="1701 71" bounds="1681 60 41 23" textPosition="1681 60"> <Properties> <displayName>GBA2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2388" reactomeId="429807" position="1789 71" bounds="1765 56 48 31" textPosition="1769 60" /> <org.gk.render.RenderableChemical id="2390" reactomeId="1861764" position="1793 361" bounds="1766 346 55 31" textPosition="1770 350" /> <org.gk.render.RenderableChemical id="2391" reactomeId="29356" position="1694 371" bounds="1673 356 43 31" textPosition="1677 360"> <Properties> <displayName>H2O</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="2393" reactomeId="1861749" position="1790 288" bounds="1770 277 41 23" textPosition="1770 277"> <Properties> <displayName>GBA3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2532" reactomeId="1861754" position="199 257" bounds="170 242 58 31" textPosition="174 246" /> <org.gk.render.RenderableChemical id="2676" reactomeId="1861779" position="2499 1148" bounds="2470 1133 58 31" textPosition="2474 1137"> <Properties> <displayName>RCOO-</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2677" reactomeId="194377" position="1670 189" bounds="1646 174 48 31" textPosition="1650 178" /> <org.gk.render.RenderableChemical id="2751" reactomeId="194653" position="758 1111" bounds="732 1096 53 31" textPosition="736 1100"> <Properties> <displayName>NAD+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="2752" reactomeId="1614312" position="756 1168" bounds="741 1157 31 23" textPosition="741 1157"> <Properties> <displayName>ARS</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="2753" reactomeId="194697" position="902 1164" bounds="876 1149 52 31" textPosition="880 1153"> <Properties> <displayName>NADH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2754" reactomeId="1663154" position="895 1123" bounds="875 1108 40 31" textPosition="879 1112"> <Properties> <displayName>H2S</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="2755" reactomeId="1614309" position="828 1207" bounds="794 1196 68 23" textPosition="794 1196"> <Properties> <displayName>active ARS</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="2756" reactomeId="1614316" position="815 1085" bounds="792 1074 47 23" textPosition="792 1074"> <Properties> <displayName>SUMF1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="2859" reactomeId="1614305" position="807 1026" bounds="784 1015 47 23" textPosition="784 1015"> <Properties> <displayName>SUMF2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="2860" reactomeId="3229251" position="2309 797" bounds="2290 786 39 23" textPosition="2290 786" /> <org.gk.render.RenderableEntitySet id="2863" reactomeId="3662340" position="2091 636" bounds="2045 625 92 23" textPosition="2045 625" bgColor="204 255 255"> <Properties> <displayName>bHEXA,bHEXB</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="2866" reactomeId="428639" position="1952 674" bounds="1921 659 62 31" textPosition="1925 663" /> <org.gk.render.RenderableChemical id="2867" reactomeId="428633" position="1691 1239" bounds="1660 1224 62 31" textPosition="1664 1228"> <Properties> <displayName>Neu5Ac</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="2868" reactomeId="4127415" position="142 325" bounds="79 314 126 23" textPosition="79 314"> <Properties> <displayName>ASAH2-like proteins</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="2938" reactomeId="29360" position="1387 253" bounds="1361 238 53 31" textPosition="1365 242" /> <org.gk.render.RenderableChemical id="2940" reactomeId="29356" position="1531 246" bounds="1510 231 43 31" textPosition="1514 235" /> <org.gk.render.RenderableChemical id="2941" reactomeId="3632881" position="1583 403" bounds="1559 388 48 31" textPosition="1563 392" /> <org.gk.render.RenderableChemical id="2942" reactomeId="73473" position="1478 418" bounds="1452 403 52 31" textPosition="1456 407" /> <org.gk.render.RenderableChemical id="2946" reactomeId="70106" position="1435 372" bounds="1417 357 36 31" textPosition="1421 361"> <Properties> <displayName>H+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2948" reactomeId="29356" position="1178 103" bounds="1157 88 43 31" textPosition="1161 92" /> <org.gk.render.RenderableProtein id="2950" reactomeId="5696096" position="1256 70" bounds="1224 59 64 23" textPosition="1224 59"> <Properties> <displayName>ALDH3B1</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.2" relativeY="0.0" label="Pa" trackId="0" reactomeId="6808462" /> <org.gk.render.RenderableFeature relativeX="0.4235294117647059" relativeY="0.0" label="GG" trackId="0" reactomeId="6808469" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2952" reactomeId="70106" position="1339 113" bounds="1321 98 36 31" textPosition="1325 102" /> <org.gk.render.RenderableChemical id="2954" reactomeId="73473" position="1363 171" bounds="1337 156 52 31" textPosition="1341 160" /> <org.gk.render.RenderableChemical id="2956" reactomeId="29360" position="1116 134" bounds="1090 119 53 31" textPosition="1094 123" /> <org.gk.render.RenderableProtein id="3096" reactomeId="5693771" position="985 190" bounds="965 179 40 23" textPosition="965 179"> <Properties> <displayName>FA2H</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3107" reactomeId="6785915" position="718 881" bounds="690 866 56 31" textPosition="694 870"> <Properties> <displayName>GalCer</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableCompartment id="3111" reactomeId="13977" position="1733 506" bounds="1643 398 181 217" textPosition="1654 569" bgColor="250 240 240" lineColor="255 153 102" insets="1651 405 164 203"> <Properties> <displayName>lipid droplet</displayName> </Properties> <Components> <Component id="3116" /> <Component id="3115" /> <Component id="3114" /> <Component id="27264" /> <Component id="27261" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="3114" reactomeId="6808468" position="1759 425" bounds="1735 410 48 31" textPosition="1739 414"> <Properties> <displayName>HXAL</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3115" reactomeId="2453691" position="1765 582" bounds="1741 567 48 31" textPosition="1745 571"> <Properties> <displayName>PALM</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="3116" reactomeId="6808466" position="1644 479" bounds="1612 468 64 23" textPosition="1612 468"> <Properties> <displayName>ALDH3B2</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.28125" relativeY="0.0" label="GG" trackId="0" reactomeId="6808460" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="3117" reactomeId="6811608" position="984 336" bounds="925 325 118 23" textPosition="925 326" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ALDH3A2-1 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="3119" reactomeId="8856243" position="264 1159" bounds="201 1141 127 37" textPosition="201 1141"> <Properties> <displayName>GD3,GM3,GT3,SM3,LacCer</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="3120" reactomeId="735700" position="405 613" bounds="372 594 67 38" textPosition="380 595"> <Properties> <displayName>UDP-GalNAc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="3121" reactomeId="8856242" position="272 1045" bounds="221 1027 103 37" textPosition="221 1027"> <Properties> <displayName>GD2,GM2, GA2,GT2,SM2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="3122" reactomeId="8856224" position="267 1103" bounds="212 1092 110 23" textPosition="212 1093" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>B4GALNT1 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="3279" reactomeId="8865571" position="736 179" bounds="695 168 83 23" textPosition="695 168"> <Properties> <displayName>ORMDL1,2,3</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="3294" reactomeId="8874349" position="1287 1040" bounds="1251 1029 73 23" textPosition="1251 1029"> <Properties> <displayName>PRKD1,2,3</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="3430" reactomeId="8879102" position="490 608" bounds="459 593 62 31" textPosition="463 597"> <Properties> <displayName>Gb3Cer</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3431" reactomeId="8879101" position="496 532" bounds="465 517 62 31" textPosition="469 521"> <Properties> <displayName>Gb4Cer</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="3432" reactomeId="8878918" position="503 572" bounds="467 561 72 23" textPosition="467 561"> <Properties> <displayName>B3GALNT1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3434" reactomeId="205687" position="437 1127" bounds="417 1112 41 31" textPosition="421 1116" /> <org.gk.render.RenderableChemical id="3438" reactomeId="8959463" position="906 503" bounds="887 488 39 31" textPosition="891 492"> <Properties> <displayName>CPE</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3440" reactomeId="9025544" position="728 602" bounds="677 587 103 31" textPosition="681 591"> <Properties> <displayName>phytoceramide</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3442" reactomeId="29356" position="607 638" bounds="586 623 43 31" textPosition="590 627" /> <org.gk.render.RenderableComplex id="3445" reactomeId="1614330" position="929 1053" bounds="896 1037 67 33" textPosition="904 1034" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>SUMF1:SUMF2</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="3504" reactomeId="1605656" position="2029 351" bounds="2005 340 49 23" textPosition="2005 341" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>bHEXA</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.ProcessNode id="3615" reactomeId="373076" position="1400 1422" bounds="1344 1393 113 59" textPosition="1344 1393"> <Properties> <displayName>Class A/1 (Rhodopsin-like receptors)</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableProtein id="3760" reactomeId="391267" position="1190 808" bounds="1167 797 47 23" textPosition="1167 797"> <Properties> <displayName>SPHK1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3779" reactomeId="428236" position="1183 676" bounds="1160 665 47 23" textPosition="1160 665"> <Properties> <displayName>SPHK2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="3878" reactomeId="9695954" position="1332 563" bounds="1280 552 104 23" textPosition="1280 552" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true"> <Properties> <displayName>SPHK2 inhibitors</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="3879" reactomeId="9695910" position="1327 648" bounds="1281 630 93 37" textPosition="1281 631" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>SPHK2:SPHK2 inhibitors</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3898" reactomeId="9840585" position="2322 75" bounds="2300 60 44 31" textPosition="2304 64"> <Properties> <displayName>GM1</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3899" reactomeId="9840584" position="2394 155" bounds="2357 140 75 31" textPosition="2361 144"> <Properties> <displayName>GM1-d18</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableCompartment id="3901" reactomeId="17940" position="2517 155" bounds="2393 101 248 108" textPosition="2478 138" bgColor="250 240 240" lineColor="255 153 102" insets="2403 111 229 89"> <Properties> <displayName>endosome</displayName> </Properties> <Components> <Component id="3899" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableCompartment id="3902" reactomeId="3828050" position="2773 452" bounds="2692 250 163 405" textPosition="2706 263" bgColor="250 240 240" lineColor="255 153 102" insets="2699 259 148 387"> <Properties> <displayName>multivesicular body, internal vesicle</displayName> </Properties> <Components> <Component id="3905" /> <Component id="4823" /> <Component id="25718" /> <Component id="25724" /> <Component id="25722" /> <Component id="26044" /> <Component id="25725" /> <Component id="26045" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="3905" reactomeId="9840481" position="2696 311" bounds="2674 296 44 31" textPosition="2678 300" /> <org.gk.render.ProcessNode id="3906" reactomeId="4085001" position="2175 72" bounds="2133 50 84 45" textPosition="2133 50"> <Properties> <displayName>Sialic acid metabolism</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableProtein id="3969" reactomeId="9840325" position="2819 711" bounds="2801 700 37 23" textPosition="2801 700"> <Properties> <displayName>PSAP</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3970" reactomeId="351333" position="2642 748" bounds="2596 737 92 23" textPosition="2596 737"> <Properties> <displayName>PSAP(60-142)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3971" reactomeId="9840328" position="2682 795" bounds="2643 782 78 27" textPosition="2646 778"> <Properties> <displayName>PSAP(405-486)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3972" reactomeId="1605602" position="2787 795" bounds="2737 784 100 23" textPosition="2737 784"> <Properties> <displayName>PSAP(311-391)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3973" reactomeId="9840336" position="2609 714" bounds="2559 703 100 23" textPosition="2559 703"> <Properties> <displayName>PSAP(195-273)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="3975" reactomeId="9840482" position="2513 647" bounds="2461 629 104 37" textPosition="2461 630" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableComplex id="4040" reactomeId="9840472" position="2521 500" bounds="2469 482 104 37" textPosition="2469 483" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):Ligands:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="4825" reactomeId="9840631" position="2600 446" bounds="2554 435 92 23" textPosition="2554 436" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GM2A:Ligands</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="4826" reactomeId="9840644" position="2264 270" bounds="2216 259 97 23" textPosition="2216 259"> <Properties> <displayName>mobilized GM1</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="4827" reactomeId="1605715" position="2280 332" bounds="2259 317 43 31" textPosition="2263 321" /> <org.gk.render.RenderableEntitySet id="4828" reactomeId="9840646" position="2056 271" bounds="2008 260 97 23" textPosition="2008 260"> <Properties> <displayName>mobilized GM2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="4833" reactomeId="3229251" position="2164 326" bounds="2145 315 39 23" textPosition="2145 315"> <Properties> <displayName>BGAL</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="5015" reactomeId="1605715" position="2011 310" bounds="1990 295 43 31" textPosition="1994 299" /> <org.gk.render.RenderableChemical id="5017" reactomeId="1605658" position="2020 395" bounds="1991 380 59 31" textPosition="1995 384" /> <org.gk.render.RenderableChemical id="5321" reactomeId="1605641" position="1946 435" bounds="1924 420 44 31" textPosition="1928 424" /> <org.gk.render.RenderableComplex id="6654" reactomeId="9840793" position="2183 424" bounds="2147 413 73 23" textPosition="2147 414" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GM2A:GA1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="6656" reactomeId="9840792" position="2184 561" bounds="2148 550 73 23" textPosition="2148 551" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GM2A:GA2</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="6718" reactomeId="1605637" position="2265 546" bounds="2247 531 36 31" textPosition="2251 535" /> <org.gk.render.RenderableChemical id="6961" reactomeId="1605715" position="2051 519" bounds="2030 504 43 31" textPosition="2034 508" /> <org.gk.render.RenderableComplex id="6962" reactomeId="9840821" position="1967 492" bounds="1915 474 104 37" textPosition="1915 475" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):GM3:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="6963" reactomeId="9840818" position="2071 717" bounds="2019 699 104 37" textPosition="2019 700" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):LacCer:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="7687" reactomeId="1605715" position="2259 589" bounds="2238 574 43 31" textPosition="2242 578" /> <org.gk.render.RenderableComplex id="7688" reactomeId="9840837" position="2182 700" bounds="2139 689 87 23" textPosition="2139 690" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GM2A:LacCer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="7750" reactomeId="1605658" position="2262 682" bounds="2233 667 59 31" textPosition="2237 671" /> <org.gk.render.RenderableEntitySet id="15734" reactomeId="3662340" position="2064 960" bounds="2018 949 92 23" textPosition="2018 949" bgColor="204 255 255" /> <org.gk.render.RenderableChemical id="16278" reactomeId="1605715" position="2102 868" bounds="2081 853 43 31" textPosition="2085 857" /> <org.gk.render.RenderableComplex id="16279" reactomeId="9840842" position="2038 1075" bounds="1986 1057 104 37" textPosition="1986 1058" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):Gb4Cer:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="16280" reactomeId="9840848" position="1996 904" bounds="1944 886 104 37" textPosition="1944 887" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):Gb3Cer:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="16586" reactomeId="3229251" position="2125 501" bounds="2106 490 39 23" textPosition="2106 490" /> <org.gk.render.RenderableProtein id="16588" reactomeId="1605614" position="2024 446" bounds="1975 435 99 23" textPosition="1975 435"> <Properties> <displayName>GM2A(32-193)</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="25712" reactomeId="9840882" position="2411 319" bounds="2375 308 72 23" textPosition="2375 309" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GM2A:SM2</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="25714" reactomeId="9840894" position="2323 409" bounds="2278 398 91 23" textPosition="2278 398"> <Properties> <displayName>bHEXA,bHEXS</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="25718" reactomeId="9840885" position="2694 466" bounds="2674 451 41 31" textPosition="2678 455"> <Properties> <displayName>BMP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="25720" reactomeId="1605658" position="2349 480" bounds="2320 465 59 31" textPosition="2324 469" /> <org.gk.render.RenderableEntitySet id="25722" reactomeId="9840942" position="2696 647" bounds="2655 636 83 23" textPosition="2655 636" /> <org.gk.render.RenderableEntitySet id="25724" reactomeId="9840941" position="2698 401" bounds="2654 390 89 23" textPosition="2654 390"> <Properties> <displayName>GM2A ligands</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="25740" reactomeId="9840879" position="2410 511" bounds="2390 496 41 31" textPosition="2394 500"> <Properties> <displayName>SM3</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="25741" reactomeId="1605715" position="2364 540" bounds="2343 525 43 31" textPosition="2347 529" /> <org.gk.render.RenderableChemical id="25743" reactomeId="1606845" position="2355 634" bounds="2324 619 63 31" textPosition="2328 623" /> <org.gk.render.RenderableComplex id="25745" reactomeId="1606814" position="2337 587" bounds="2281 576 113 23" textPosition="2281 577" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="25748" reactomeId="1605715" position="1939 1060" bounds="1918 1045 43 31" textPosition="1922 1049" /> <org.gk.render.RenderableChemical id="25754" reactomeId="1605715" position="2446 1063" bounds="2425 1048 43 31" textPosition="2429 1052" /> <org.gk.render.RenderableChemical id="25756" reactomeId="1605745" position="2779 1012" bounds="2762 997 35 31" textPosition="2766 1001" /> <org.gk.render.RenderableChemical id="25761" reactomeId="1605715" position="2451 759" bounds="2430 744 43 31" textPosition="2434 748" /> <org.gk.render.RenderableEntitySet id="25762" reactomeId="9840969" position="2381 728" bounds="2332 717 98 23" textPosition="2332 717"> <Properties> <displayName>Sap B/C:LacCer</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="25764" reactomeId="9840964" position="2406 864" bounds="2358 853 97 23" textPosition="2358 853"> <Properties> <displayName>Sap B/C:GlcCer</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="25767" reactomeId="1605637" position="2333 840" bounds="2315 825 36 31" textPosition="2319 829"> <Properties> <displayName>Gal</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="25769" reactomeId="1605715" position="2645 868" bounds="2624 853 43 31" textPosition="2628 857" /> <org.gk.render.RenderableChemical id="25775" reactomeId="1605592" position="2724 856" bounds="2697 841 55 31" textPosition="2701 845" /> <org.gk.render.RenderableComplex id="25780" reactomeId="9840996" position="2230 760" bounds="2178 742 104 37" textPosition="2178 743" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):Sulfatide:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="25781" reactomeId="1605715" position="2090 779" bounds="2069 764 43 31" textPosition="2073 768" /> <org.gk.render.RenderableEntitySet id="25782" reactomeId="9840939" position="2325 925" bounds="2284 914 83 23" textPosition="2284 914"> <Properties> <displayName>PE 30,32,34</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="25952" reactomeId="9841186" position="1951 1167" bounds="1899 1149 104 37" textPosition="1899 1150" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):Gal2Cer:PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="25955" reactomeId="1605744" position="2052 1197" bounds="2017 1186 70 23" textPosition="2017 1187" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableEntitySet id="25958" reactomeId="9840939" position="2139 1199" bounds="2098 1188 83 23" textPosition="2098 1188" /> <org.gk.render.RenderableComplex id="25960" reactomeId="9840482" position="2207 1158" bounds="2155 1140 104 37" textPosition="2155 1141" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273) dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="25962" reactomeId="1605637" position="2208 1108" bounds="2190 1093 36 31" textPosition="2194 1097" /> <org.gk.render.RenderableProtein id="25966" reactomeId="6814613" position="1749 846" bounds="1728 835 42 23" textPosition="1728 835"> <Properties> <displayName>M6PR</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableCompartment id="25968" reactomeId="432051" position="1740 786" bounds="1665 721 151 131" textPosition="1685 769" bgColor="250 240 240" lineColor="255 153 102" insets="1675 731 132 112"> <Properties> <displayName>transport vesicle</displayName> </Properties> <Components> <Component id="25966" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="25988" reactomeId="29356" position="607 945" bounds="586 930 43 31" textPosition="590 934" /> <org.gk.render.RenderableChemical id="26031" reactomeId="70106" position="210 598" bounds="192 583 36 31" textPosition="196 587" /> <org.gk.render.RenderableChemical id="26033" reactomeId="70106" position="791 726" bounds="773 711 36 31" textPosition="777 715" /> <org.gk.render.RenderableChemical id="26036" reactomeId="428040" position="2617 949" bounds="2599 934 36 31" textPosition="2603 938" /> <org.gk.render.RenderableComplex id="26037" reactomeId="9842117" position="2641 577" bounds="2602 560 79 35" textPosition="2606 559" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PSAP(195-273):PE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="26044" reactomeId="9842141" position="2699 524" bounds="2647 506 104 37" textPosition="2647 506"> <Properties> <displayName>PSAP(195-273) ligands</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="26202" reactomeId="1500578" position="723 140" bounds="689 125 69 31" textPosition="693 129"> <Properties> <displayName>acyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26203" reactomeId="9841798" position="720 261" bounds="664 246 113 31" textPosition="668 250"> <Properties> <displayName>3-ketosphingoid</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26206" reactomeId="5279323" position="586 384" bounds="534 369 105 31" textPosition="538 373"> <Properties> <displayName>sphingoid base</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26216" reactomeId="9842380" position="1183 481" bounds="1144 466 78 31" textPosition="1148 470"> <Properties> <displayName>(4E)-CERA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26219" reactomeId="1500578" position="674 383" bounds="640 368 69 31" textPosition="644 372" /> <org.gk.render.RenderableChemical id="26232" reactomeId="5279322" position="1316 763" bounds="1297 748 38 31" textPosition="1301 752"> <Properties> <displayName>S1P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="26298" reactomeId="9842697" position="984 560" bounds="944 549 81 23" textPosition="944 550" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableComplex id="26299" reactomeId="9842694" position="1100 488" bounds="1060 477 81 23" textPosition="1060 478" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="26303" reactomeId="29356" position="1256 490" bounds="1235 475 43 31" textPosition="1239 479" /> <org.gk.render.RenderableChemical id="26307" reactomeId="70106" position="653 117" bounds="635 102 36 31" textPosition="639 106" /> <org.gk.render.RenderableComplex id="26333" reactomeId="9842694" position="565 608" bounds="525 597 81 23" textPosition="525 598" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>CYB5B:Fe3+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="26334" reactomeId="9842697" position="570 502" bounds="530 491 81 23" textPosition="530 492" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>CYB5B:Fe2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="26335" reactomeId="9843199" position="1095 257" bounds="1035 235 120 45" textPosition="1039 239"> <Properties> <displayName>2-saturated fatty acid</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26336" reactomeId="9843201" position="1075 103" bounds="1041 88 68 31" textPosition="1045 92"> <Properties> <displayName>2-OH FA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26337" reactomeId="29356" position="1001 108" bounds="980 93 43 31" textPosition="984 97" /> <org.gk.render.RenderableComplex id="26344" reactomeId="9842697" position="982 241" bounds="942 230 81 23" textPosition="942 231" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableComplex id="26346" reactomeId="9842694" position="876 145" bounds="836 134 81 23" textPosition="836 135" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="26348" reactomeId="29368" position="1090 185" bounds="1073 170 34 31" textPosition="1077 174"> <Properties> <displayName>O2</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26350" reactomeId="70106" position="1163 223" bounds="1145 208 36 31" textPosition="1149 212" /> <org.gk.render.RenderableChemical id="26357" reactomeId="1524057" position="278 558" bounds="257 543 43 31" textPosition="261 547"> <Properties> <displayName>DAG</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26367" reactomeId="9843210" position="125 365" bounds="101 350 49 31" textPosition="105 354" /> <org.gk.render.RenderableChemical id="26509" reactomeId="9843247" position="946 420" bounds="931 405 31 31" textPosition="935 409"> <Properties> <displayName>PE</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26513" reactomeId="9843232" position="863 411" bounds="820 396 86 31" textPosition="824 400"> <Properties> <displayName>C16DH CER</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="26514" reactomeId="9843234" position="987 463" bounds="943 452 89 23" textPosition="943 453" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>SAMD8 trimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="26516" reactomeId="29370" position="1256 809" bounds="1236 794 41 31" textPosition="1240 798" /> <org.gk.render.RenderableChemical id="26517" reactomeId="114519" position="127 465" bounds="106 450 43 31" textPosition="110 454" /> <org.gk.render.RenderableEntitySet id="26518" reactomeId="9843705" position="1194 1345" bounds="1147 1334 95 23" textPosition="1147 1334"> <Properties> <displayName>SPNS2,MFSD2B</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="26527" reactomeId="70106" position="1342 804" bounds="1324 789 36 31" textPosition="1328 793" /> <org.gk.render.RenderableChemical id="26531" reactomeId="113592" position="1073 795" bounds="1053 780 40 31" textPosition="1057 784" /> <org.gk.render.RenderableChemical id="26533" reactomeId="428682" position="1032 771" bounds="1013 756 39 31" textPosition="1017 760" /> <org.gk.render.RenderableChemical id="26535" reactomeId="113592" position="1075 728" bounds="1055 713 40 31" textPosition="1059 717" /> <org.gk.render.RenderableChemical id="26539" reactomeId="70106" position="1327 693" bounds="1309 678 36 31" textPosition="1313 682" /> <org.gk.render.RenderableChemical id="26540" reactomeId="29370" position="1361 726" bounds="1341 711 41 31" textPosition="1345 715"> <Properties> <displayName>ADP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26542" reactomeId="29356" position="1421 1262" bounds="1400 1247 43 31" textPosition="1404 1251" /> <org.gk.render.RenderableChemical id="26543" reactomeId="113592" position="1405 1298" bounds="1385 1283 40 31" textPosition="1389 1287"> <Properties> <displayName>ATP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26544" reactomeId="29370" position="1526 1256" bounds="1506 1241 41 31" textPosition="1510 1245" /> <org.gk.render.RenderableEntitySet id="26545" reactomeId="9843735" position="1372 1342" bounds="1326 1331 92 23" textPosition="1326 1331"> <Properties> <displayName>ABCC1,ABCG2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="26547" reactomeId="70106" position="1486 1227" bounds="1468 1212 36 31" textPosition="1472 1216" /> <org.gk.render.RenderableChemical id="26550" reactomeId="29372" position="1559 1290" bounds="1546 1275 27 31" textPosition="1550 1279" /> <org.gk.render.RenderableChemical id="26551" reactomeId="9843733" position="1291 1418" bounds="1272 1403 38 31" textPosition="1276 1407" /> <org.gk.render.RenderableChemical id="26574" reactomeId="9843855" position="723 641" bounds="656 626 134 31" textPosition="660 630"> <Properties> <displayName>phytoceramide-C16</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="26578" reactomeId="9843868" position="742 690" bounds="682 679 121 23" textPosition="682 680" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ACER3:Ca2+:Zn2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="26580" reactomeId="1861754" position="1113 688" bounds="1084 673 58 31" textPosition="1088 677" /> <org.gk.render.RenderableChemical id="26582" reactomeId="1861754" position="630 860" bounds="601 845 58 31" textPosition="605 849" /> <org.gk.render.RenderableChemical id="26589" reactomeId="29356" position="1321 858" bounds="1300 843 43 31" textPosition="1304 847" /> <org.gk.render.RenderableChemical id="26593" reactomeId="428682" position="573 821" bounds="554 806 39 31" textPosition="558 810" /> <org.gk.render.RenderableEntitySet id="26594" reactomeId="9844328" position="1250 368" bounds="1219 357 62 23" textPosition="1219 357"> <Properties> <displayName>S1P,SPAP</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="26597" reactomeId="9844327" position="1260 197" bounds="1214 186 93 23" textPosition="1214 186"> <Properties> <displayName>HXAL,HD2NAL</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="26612" reactomeId="1132148" position="1659 1202" bounds="1617 1187 85 31" textPosition="1621 1191"> <Properties> <displayName>sphingosine</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="26640" reactomeId="9844570" position="995 707" bounds="974 696 42 23" textPosition="974 696"> <Properties> <displayName>UGT8</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="26642" reactomeId="428256" position="984 936" bounds="960 921 48 31" textPosition="964 925" /> <org.gk.render.RenderableChemical id="26644" reactomeId="1981137" position="872 669" bounds="839 654 67 31" textPosition="843 658"> <Properties> <displayName>UDP-Gal</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26645" reactomeId="158602" position="952 789" bounds="932 774 41 31" textPosition="936 778" /> <org.gk.render.RenderableChemical id="26652" reactomeId="741440" position="377 364" bounds="355 349 45 31" textPosition="359 353"> <Properties> <displayName>PAPS</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26653" reactomeId="425969" position="372 563" bounds="354 548 36 31" textPosition="358 552" /> <org.gk.render.RenderableProtein id="26656" reactomeId="1631586" position="285 401" bounds="254 390 62 23" textPosition="254 390"> <Properties> <displayName>GAL3ST1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="26657" reactomeId="742343" position="379 441" bounds="360 426 39 31" textPosition="364 430"> <Properties> <displayName>PAP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26711" reactomeId="727815" position="423 284" bounds="376 269 94 31" textPosition="380 273"> <Properties> <displayName>CMP-Neu5Ac</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="26712" reactomeId="9844855" position="284 301" bounds="222 283 124 37" textPosition="222 283"> <Properties> <displayName>LacCer/GalCer/GA1/GA2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="26714" reactomeId="9844871" position="285 211" bounds="246 200 78 23" textPosition="246 200"> <Properties> <displayName>GM1/2/3/4</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="26715" reactomeId="727810" position="411 221" bounds="390 206 42 31" textPosition="394 210"> <Properties> <displayName>CMP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="26716" reactomeId="4086268" position="275 257" bounds="244 246 62 23" textPosition="244 246"> <Properties> <displayName>ST3GAL5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="26718" reactomeId="425969" position="351 181" bounds="333 166 36 31" textPosition="337 170" /> <org.gk.render.RenderableChemical id="26972" reactomeId="9844975" position="501 1024" bounds="462 1009 79 31" textPosition="466 1013"> <Properties> <displayName>CERA-d18</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="26991" reactomeId="428270" position="508 485" bounds="484 470 48 31" textPosition="488 474" /> <org.gk.render.RenderableChemical id="26993" reactomeId="735682" position="439 1197" bounds="406 1182 67 31" textPosition="410 1186" /> <org.gk.render.RenderableChemical id="26994" reactomeId="9844874" position="269 1221" bounds="226 1206 87 31" textPosition="230 1210"> <Properties> <displayName>LacCer-d18</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="26995" reactomeId="9845280" position="374 1311" bounds="336 1300 77 23" textPosition="336 1300"> <Properties> <displayName>B4GALT5/6</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="26997" reactomeId="425969" position="311 1272" bounds="293 1257 36 31" textPosition="297 1261" /> <org.gk.render.RenderableChemical id="26999" reactomeId="205687" position="341 1202" bounds="321 1187 41 31" textPosition="325 1191" /> <org.gk.render.RenderableEntitySet id="27138" reactomeId="9845491" position="281 357" bounds="236 346 91 23" textPosition="236 346"> <Properties> <displayName>GalCer,LacCer</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="27142" reactomeId="9845488" position="279 440" bounds="249 429 61 23" textPosition="249 429"> <Properties> <displayName>SM3,SM4</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="27162" reactomeId="425969" position="402 1073" bounds="384 1058 36 31" textPosition="388 1062" /> <org.gk.render.RenderableChemical id="27165" reactomeId="735700" position="384 1157" bounds="348 1138 72 39" textPosition="359 1139" /> <org.gk.render.RenderableEntitySet id="27174" reactomeId="9845519" position="258 992" bounds="211 981 95 23" textPosition="211 981"> <Properties> <displayName>GM2,GD2,GA2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="27177" reactomeId="9845510" position="264 899" bounds="213 888 103 23" textPosition="213 888"> <Properties> <displayName>GM1,GD1b,GA1</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="27179" reactomeId="913716" position="279 948" bounds="248 937 63 23" textPosition="248 937"> <Properties> <displayName>B3GALT4</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="27181" reactomeId="425969" position="433 944" bounds="415 929 36 31" textPosition="419 933" /> <org.gk.render.RenderableChemical id="27183" reactomeId="735682" position="347 1007" bounds="314 992 67 31" textPosition="318 996" /> <org.gk.render.RenderableEntitySet id="27191" reactomeId="9845541" position="266 803" bounds="207 792 118 23" textPosition="207 792"> <Properties> <displayName>GD1a,GM1b,GT1b</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="27192" reactomeId="9845546" position="279 849" bounds="242 838 74 23" textPosition="242 838"> <Properties> <displayName>ST3GAL2,3</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="27195" reactomeId="425969" position="395 808" bounds="377 793 36 31" textPosition="381 797" /> <org.gk.render.RenderableChemical id="27197" reactomeId="727815" position="400 903" bounds="353 888 94 31" textPosition="357 892" /> <org.gk.render.RenderableChemical id="27199" reactomeId="727810" position="396 759" bounds="375 744 42 31" textPosition="379 748" /> <org.gk.render.RenderableChemical id="27201" reactomeId="205687" position="396 500" bounds="376 485 41 31" textPosition="380 489" /> <org.gk.render.RenderableEntitySet id="27223" reactomeId="9845581" position="505 867" bounds="460 846 90 42" textPosition="463 849"> <Properties> <displayName>GM1b,GD1a,GD3,GT1b</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="27225" reactomeId="9845591" position="516 761" bounds="460 743 112 37" textPosition="460 743"> <Properties> <displayName>GQ1b,GT3,GD1c,GT1a</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="27227" reactomeId="4086339" position="492 814" bounds="464 803 56 23" textPosition="464 803"> <Properties> <displayName>ST8SIA5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="27231" reactomeId="29356" position="1092 616" bounds="1071 601 43 31" textPosition="1075 605" /> <org.gk.render.RenderableChemical id="27249" reactomeId="29356" position="1529 1192" bounds="1508 1177 43 31" textPosition="1512 1181" /> <org.gk.render.RenderableChemical id="27251" reactomeId="29372" position="1646 1151" bounds="1633 1136 27 31" textPosition="1637 1140" /> <org.gk.render.RenderableChemical id="27262" reactomeId="29356" position="1854 472" bounds="1833 457 43 31" textPosition="1837 461" /> <org.gk.render.RenderableChemical id="27264" reactomeId="70106" position="1704 559" bounds="1686 544 36 31" textPosition="1690 548" /> <org.gk.render.RenderableChemical id="27266" reactomeId="29360" position="1854 426" bounds="1828 411 53 31" textPosition="1832 415" /> <org.gk.render.RenderableChemical id="27274" reactomeId="70106" position="1234 1211" bounds="1216 1196 36 31" textPosition="1220 1200" /> <org.gk.render.RenderableChemical id="27280" reactomeId="70106" position="1229 1125" bounds="1211 1110 36 31" textPosition="1215 1114" /> <org.gk.render.RenderableChemical id="27283" reactomeId="1500596" position="720 472" bounds="699 457 43 31" textPosition="703 461" /> <org.gk.render.RenderableChemical id="27307" reactomeId="156540" position="936 835" bounds="918 820 36 31" textPosition="922 824" /> <org.gk.render.RenderableChemical id="27311" reactomeId="70106" position="240 152" bounds="222 137 36 31" textPosition="226 141" /> <org.gk.render.RenderableChemical id="27315" reactomeId="156540" position="933 1208" bounds="915 1193 36 31" textPosition="919 1197" /> <org.gk.render.RenderableChemical id="27317" reactomeId="428040" position="2174 912" bounds="2156 897 36 31" textPosition="2160 901" /> <org.gk.render.RenderableChemical id="27324" reactomeId="9845551" position="500 200" bounds="474 185 52 31" textPosition="478 189"> <Properties> <displayName>GM1b</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="27325" reactomeId="9846309" position="399 147" bounds="362 132 75 31" textPosition="366 136"> <Properties> <displayName>GD1alpha</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="27326" reactomeId="9846310" position="513 149" bounds="464 138 99 23" textPosition="464 138"> <Properties> <displayName>ST6GALNAC5,6</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="27334" reactomeId="9846337" position="267 758" bounds="235 747 65 23" textPosition="235 747"> <Properties> <displayName>GM1,GA1</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="27336" reactomeId="205683" position="338 751" bounds="311 734 55 34" textPosition="318 733"> <Properties> <displayName>GDP-Fuc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="27337" reactomeId="9846331" position="262 661" bounds="219 644 86 35" textPosition="227 644"> <Properties> <displayName>Fuc-GM1, Fuc-GA1</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="27338" reactomeId="205689" position="324 616" bounds="303 601 42 31" textPosition="307 605"> <Properties> <displayName>GDP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="27348" reactomeId="9846476" position="501 660" bounds="473 649 56 23" textPosition="473 649"> <Properties> <displayName>A4GALT</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="27350" reactomeId="9844874" position="489 711" bounds="452 694 75 35" textPosition="462 694" /> <org.gk.render.RenderableChemical id="27352" reactomeId="735682" position="412 716" bounds="379 701 67 31" textPosition="383 705" /> <org.gk.render.RenderableChemical id="27354" reactomeId="205687" position="382 659" bounds="362 644 41 31" textPosition="366 648"> <Properties> <displayName>UDP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="27361" reactomeId="9846503" position="499 314" bounds="471 299 57 31" textPosition="475 303"> <Properties> <displayName>Lc3Cer</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="27362" reactomeId="9846502" position="505 386" bounds="476 375 58 23" textPosition="476 375"> <Properties> <displayName>B3GNT5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="27365" reactomeId="9844874" position="521 429" bounds="478 414 87 31" textPosition="482 418" /> <org.gk.render.RenderableChemical id="27367" reactomeId="205687" position="393 324" bounds="373 309 41 31" textPosition="377 313" /> <org.gk.render.RenderableChemical id="27369" reactomeId="425969" position="436 336" bounds="418 321 36 31" textPosition="422 325" /> <org.gk.render.RenderableEntitySet id="27370" reactomeId="9034070" position="264 710" bounds="239 699 51 23" textPosition="239 699"> <Properties> <displayName>FUT1,2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="27371" reactomeId="914003" position="439 439" bounds="405 419 68 40" textPosition="414 421"> <Properties> <displayName>UDP-GlcNAc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="27411" reactomeId="29370" position="1234 1250" bounds="1214 1235 41 31" textPosition="1218 1239" /> <org.gk.render.ProcessNode id="27418" reactomeId="9845576" position="619 1291" bounds="554 1265 130 53" textPosition="558 1269"> <Properties> <displayName>Glycosphingolipid transport</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableChemical id="27428" reactomeId="29356" position="1028 1185" bounds="1007 1170 43 31" textPosition="1011 1174" /> </Nodes> <Edges> <org.gk.render.RenderableReaction id="4" reactomeId="428127" points="647 167, 636 190, 636 219" position="636 190" lineWidth="1.0"> <Inputs> <Input id="5" points="610 129" /> <Input id="26202" points="686 152" /> <Input id="26307" points="651 136" /> </Inputs> <Outputs> <Output id="26203" points="689 243" /> <Output id="7" points="573 206" /> <Output id="9" points="571 235" /> </Outputs> <Catalysts> <Catalyst id="10" points="692 198" /> </Catalysts> <Inhibitors> <Inhibitor id="3279" points="689 183" /> </Inhibitors> <Properties> <displayName>SPTLC complexes transfer acyl-CoA onto serine</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="17" reactomeId="428123" points="644 283, 645 301, 645 322" position="645 301" lineWidth="1.0"> <Inputs> <Input id="19" points="637 269" /> <Input id="26203" points="666 280" /> <Input id="18" points="577 281" /> </Inputs> <Outputs> <Output id="26206" points="600 366" /> <Output id="20" points="582 334" /> </Outputs> <Catalysts> <Catalyst id="22" points="698 300" /> </Catalysts> <Properties> <displayName>KDSR reduces 3-ketosphingoid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="24" reactomeId="428185" points="637 411, 638 430, 639 457" position="638 430" lineWidth="1.0"> <Inputs> <Input id="26206" points="615 403" /> <Input id="26219" points="653 402" /> </Inputs> <Outputs> <Output id="26" points="705 497" /> <Output id="28" points="610 460" /> <Output id="36" points="654 489" /> </Outputs> <Catalysts> <Catalyst id="27" points="651 430" /> </Catalysts> <Properties> <displayName>Ceramide synthases transfer acyl-CoA onto sphingoid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="29" reactomeId="428260" points="635 545, 635 573, 634 600" position="635 573" lineWidth="1.0"> <Inputs> <Input id="26" points="702 522" /> <Input id="30" points="604 543" /> <Input id="26334" points="587 517" /> <Input id="36" points="650 526" /> </Inputs> <Outputs> <Output id="3440" points="674 600" /> <Output id="26333" points="609 603" /> <Output id="3442" points="618 620" /> </Outputs> <Catalysts> <Catalyst id="33" points="708 563" /> </Catalysts> <Properties> <displayName>DEGS2 oxygenates dihydroceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="43" reactomeId="428259" points="1182 550, 1181 534, 1183 520" position="1181 534" lineWidth="1.0"> <Inputs> <Input id="26298" stoichiometry="2" points="1028 557" /> <Input id="50" stoichiometry="2" points="1157 572" /> <Input id="51" points="1199 563" /> <Input id="26" points="758 516" /> </Inputs> <Outputs> <Output id="26299" stoichiometry="2" points="1129 503" /> <Output id="26303" stoichiometry="2" points="1232 498" /> <Output id="26216" points="1183 500" /> </Outputs> <Catalysts> <Catalyst id="48" points="1008 516" /> </Catalysts> <Properties> <displayName>DEGS1 dehydrogenates dihydroceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="63" reactomeId="428273" points="1099 768, 1190 767, 1236 767" position="1190 767" lineWidth="1.0"> <Inputs> <Input id="26531" points="1087 777" /> <Input id="26533" points="1055 770" /> </Inputs> <Outputs> <Output id="26232" points="1294 763" /> <Output id="26516" points="1248 791" /> <Output id="26527" points="1321 797" /> </Outputs> <Catalysts> <Catalyst id="3760" points="1190 794" /> </Catalysts> <Properties> <displayName>SPHK1 phosphorylates sphingoid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="112" reactomeId="429698" points="1209 1015, 1208 1041, 1207 1062" position="1208 1041" lineWidth="1.0"> <Inputs> <Input id="113" points="1228 1005" /> <Input id="111" points="1184 1002" /> </Inputs> <Outputs> <Output id="114" points="1167 1082" /> <Output id="27280" points="1223 1107" /> <Output id="115" points="1234 1079" /> </Outputs> <Catalysts> <Catalyst id="3294" points="1245 1040" /> </Catalysts> <Properties> <displayName>PRKD1,2,3 phosphorylates CERT1-2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="117" reactomeId="429714" points="1147 1163, 1147 1178, 1148 1206" position="1147 1178" lineWidth="1.0"> <Inputs> <Input id="114" points="1147 1111" /> <Input id="118" stoichiometry="2" points="1124 1150" /> </Inputs> <Outputs> <Output id="27411" stoichiometry="2" points="1211 1239" /> <Output id="120" points="1148 1247" /> <Output id="27274" stoichiometry="2" points="1213 1209" /> </Outputs> <Catalysts> <Catalyst id="121" points="1196 1177" /> </Catalysts> <Properties> <displayName>CSNK1G2 phosphorylates p-CERT1-2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="128" reactomeId="429798" points="340 501, 340 527, 341 563" position="340 527" lineWidth="1.0"> <Inputs> <Input id="129" points="300 484" /> <Input id="26991" points="481 480, 395 466" /> </Inputs> <Outputs> <Output id="131" points="299 586" /> <Output id="26357" points="303 559" /> </Outputs> <Catalysts> <Catalyst id="132" points="309 521" /> </Catalysts> <Properties> <displayName>SGMS1 transfers phosphocholine onto ceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="134" reactomeId="429786" points="190 557, 202 508, 202 482" position="202 508" lineWidth="1.0"> <Inputs> <Input id="135" points="149 556" /> <Input id="136" points="149 592" /> </Inputs> <Outputs> <Output id="26367" points="138 384, 184 433" /> <Output id="26517" points="152 469" /> </Outputs> <Catalysts> <Catalyst id="139" points="186 509" /> </Catalysts> <Properties> <displayName>SGMS2 transfers phosphocholine onto ceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="143" reactomeId="1605624" points="2165 272, 2163 270, 2165 270" position="2163 270" lineWidth="1.0"> <Inputs> <Input id="4826" points="2210 270" /> <Input id="4827" points="2256 320" /> </Inputs> <Outputs> <Output id="4828" points="2111 270" /> <Output id="147" points="2110 302" /> </Outputs> <Catalysts> <Catalyst id="4833" points="2163 309" /> </Catalysts> <Properties> <displayName>Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="153" reactomeId="1605595" points="1945 335, 1945 353, 1945 374" position="1945 353" lineWidth="1.0"> <Inputs> <Input id="152" points="1945 287" /> <Input id="5015" points="1987 318" /> </Inputs> <Outputs> <Output id="5017" points="1988 386" /> <Output id="5321" points="1945 417" /> <Output id="16588" points="2011 432" /> </Outputs> <Catalysts> <Catalyst id="3504" points="2002 351" /> </Catalysts> <Properties> <displayName>bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="275" reactomeId="1605632" points="1991 1041, 1990 993, 1990 969" position="1990 993" lineWidth="1.0"> <Inputs> <Input id="16279" points="2012 1054" /> <Input id="25748" points="1964 1052" /> </Inputs> <Outputs> <Output id="156" points="1969 960" /> <Output id="16280" points="1994 926" /> </Outputs> <Catalysts> <Catalyst id="15734" points="2038 978" /> </Catalysts> <Properties> <displayName>bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="280" reactomeId="1605736" points="1995 854, 1993 822, 1993 796" position="1993 822" lineWidth="1.0"> <Inputs> <Input id="16280" points="1995 883" /> <Input id="16278" points="2078 865" /> </Inputs> <Outputs> <Output id="6963" points="2052 739" /> <Output id="284" points="1962 765" /> </Outputs> <Catalysts> <Catalyst id="283" points="1961 823" /> </Catalysts> <Properties> <displayName>GLA hydrolyzes PSAP(195-273):Gb3Cer:PE</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="285" reactomeId="1605724" points="2014 564, 2013 595, 2014 630" position="2013 595" lineWidth="1.0"> <Inputs> <Input id="6961" points="2038 538" /> <Input id="6962" points="1979 514" /> </Inputs> <Outputs> <Output id="2866" points="1973 656" /> <Output id="6963" points="2058 696" /> </Outputs> <Catalysts> <Catalyst id="288" points="1975 595" /> </Catalysts> <Properties> <displayName>NEU1,4 hydrolyze PSAP(195-273):GM3:PE</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="290" reactomeId="1605723" points="1746 1095, 1746 1116, 1746 1151" position="1746 1116" lineWidth="1.0"> <Inputs> <Input id="291" points="1723 1068" /> <Input id="292" points="1775 1067" /> </Inputs> <Outputs> <Output id="2867" points="1700 1221" /> <Output id="294" points="1776 1161" /> </Outputs> <Catalysts> <Catalyst id="295" points="1788 1116" /> </Catalysts> <Properties> <displayName>NEU2 cleaves GM3 to form LacCer (cytosol)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="297" reactomeId="1605768" points="1781 1284, 1747 1284, 1711 1284" position="1747 1284" lineWidth="1.0"> <Inputs> <Input id="298" points="1802 1320" /> <Input id="299" points="1799 1259" /> </Inputs> <Outputs> <Output id="300" points="1695 1319" /> <Output id="2867" points="1697 1258" /> </Outputs> <Catalysts> <Catalyst id="301" points="1746 1313" /> </Catalysts> <Properties> <displayName>NEU3 cleaves GM3 to form LacCer (plasma membrane)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="346" reactomeId="1606312" points="2404 776, 2404 796, 2405 814" position="2404 796" lineWidth="1.0"> <Inputs> <Input id="25761" points="2427 766" /> <Input id="25762" points="2386 746" /> </Inputs> <Outputs> <Output id="25764" points="2405 847" /> <Output id="25767" points="2354 833" /> </Outputs> <Catalysts> <Catalyst id="2860" points="2335 796" /> </Catalysts> <Properties> <displayName>GLB1 hydrolyzes SapB/C:LacCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="352" reactomeId="1605591" points="2719 891, 2719 944, 2719 975" position="2719 944" lineWidth="1.0"> <Inputs> <Input id="25775" points="2721 875" /> <Input id="25769" points="2670 874" /> </Inputs> <Outputs> <Output id="356" points="2432 1022" /> <Output id="25756" points="2759 1001" /> </Outputs> <Catalysts> <Catalyst id="357" points="2818 942" /> </Catalysts> <Properties> <displayName>GBA1:SAPC hydrolyzes GlcCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="358" reactomeId="1606564" points="2262 1002, 2282 1001, 2303 1002" position="2282 1001" lineWidth="1.0"> <Inputs> <Input id="359" points="2237 1002" /> <Input id="360" points="2246 979" /> </Inputs> <Outputs> <Output id="356" points="2378 1020" /> <Output id="355" points="2312 1021" /> </Outputs> <Catalysts> <Catalyst id="361" points="2282 1054" /> </Catalysts> <Activators> <Activator id="3970" points="2615 763, 2514 803, 2449 953, 2343 954" /> </Activators> <Properties> <displayName>GALC hydrolyzes GalCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="363" reactomeId="1606602" points="2405 1072, 2404 1095, 2404 1119" position="2404 1095" lineWidth="1.0"> <Inputs> <Input id="356" points="2405 1045" /> <Input id="25754" points="2422 1067" /> </Inputs> <Outputs> <Output id="366" points="2404 1141" /> <Output id="2676" points="2467 1139" /> </Outputs> <Catalysts> <Catalyst id="367" points="2369 1094" /> </Catalysts> <Activators> <Activator id="3971" points="2640 798, 2518 808, 2453 959, 2351 959, 2351 1053" /> </Activators> <Properties> <displayName>ASAH1 hydrolyzes ceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="368" reactomeId="1606583" points="67 385, 66 323, 67 296" position="66 323" lineWidth="1.0"> <Inputs> <Input id="135" points="95 544, 66 528" /> <Input id="1267" points="186 400" /> </Inputs> <Outputs> <Output id="371" points="111 259" /> <Output id="2532" points="167 265" /> </Outputs> <Catalysts> <Catalyst id="2868" points="73 323" /> </Catalysts> <Properties> <displayName>ASAH2 hydrolyzes ceramide (plasma membrane)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="394" reactomeId="1606807" points="2224 813, 2225 835, 2224 856" position="2225 835" lineWidth="1.0"> <Inputs> <Input id="25780" points="2227 782" /> <Input id="25781" points="2115 784" /> </Inputs> <Outputs> <Output id="359" points="2207 984" /> <Output id="3975" points="2512 669, 2505 806, 2462 907" /> <Output id="25782" points="2308 908" /> <Output id="397" points="2195 861" /> <Output id="27317" points="2187 894" /> </Outputs> <Catalysts> <Catalyst id="398" points="2194 829" /> </Catalysts> <Properties> <displayName>ARSA removes sulfate from PSAP(195-273):Sulfatide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="438" reactomeId="1605797" points="2547 886, 2547 907, 2546 928" position="2547 907" lineWidth="1.0"> <Inputs> <Input id="439" points="2555 858" /> <Input id="25769" points="2621 871" /> </Inputs> <Outputs> <Output id="356" points="2427 1008" /> <Output id="441" points="2546 960" /> <Output id="26036" points="2596 943" /> </Outputs> <Catalysts> <Catalyst id="442" points="2594 906" /> </Catalysts> <Properties> <displayName>SMPD1 hydrolyzes SPHM</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="444" reactomeId="1606273" points="55 413, 55 593, 82 580" position="55 593" lineWidth="1.0"> <Inputs> <Input id="137" points="70 417" /> <Input id="1267" points="186 404" /> </Inputs> <Outputs> <Output id="135" points="95 570" /> <Output id="456" points="119 633" /> <Output id="26031" points="189 595" /> </Outputs> <Catalysts> <Catalyst id="447" points="111 681" /> </Catalysts> <Properties> <displayName>SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="475" reactomeId="1606288" points="790 806, 789 787, 788 764" position="789 787" lineWidth="1.0"> <Inputs> <Input id="476" points="754 820" /> <Input id="477" points="814 812" /> </Inputs> <Outputs> <Output id="46" points="959 601, 830 611, 828 755" /> <Output id="478" points="748 752" /> <Output id="26033" points="789 745" /> </Outputs> <Catalysts> <Catalyst id="479" points="767 787" /> </Catalysts> <Properties> <displayName>SMPD4 hydrolyzes sphingomyelin (ER membrane)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1241" reactomeId="1638104" points="460 1048, 460 1063, 452 1086" position="460 1063" lineWidth="1.0"> <Inputs> <Input id="26972" points="474 1043" /> <Input id="1242" points="442 1040" /> </Inputs> <Outputs> <Output id="2102" points="493 1231" /> <Output id="3434" points="442 1109" /> <Output id="27162" points="423 1077" /> </Outputs> <Catalysts> <Catalyst id="1245" points="479 1062" /> </Catalysts> <Properties> <displayName>UGCG transfers glucose to ceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1254" reactomeId="1638845" points="174 184, 173 161, 173 142" position="173 161" lineWidth="1.0"> <Inputs> <Input id="135" points="95 551, 34 541, 36 228" /> <Input id="1255" points="190 195" /> </Inputs> <Outputs> <Output id="1257" points="142 114" /> <Output id="27311" points="219 149" /> <Output id="1256" points="194 124" /> </Outputs> <Catalysts> <Catalyst id="1258" points="147 162" /> </Catalysts> <Properties> <displayName>CERK phosphorylates CERA to form C1P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1307" reactomeId="1640164" points="217 475, 219 517, 213 537" position="219 517" lineWidth="1.0"> <Inputs> <Input id="137" points="151 449" /> <Input id="1267" points="211 422" /> </Inputs> <Outputs> <Output id="135" points="149 550" /> <Output id="456" points="141 633" /> <Output id="26031" points="210 580" /> </Outputs> <Catalysts> <Catalyst id="1309" points="148 731, 198 702, 198 640, 238 616, 248 516" /> </Catalysts> <Properties> <displayName>ENPP7 hydrolyzes sphingomyelin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="2375" points="1546 1339, 1565 1337" position="1555 1338" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="85" /> </Inputs> <Outputs> <Output id="79" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="2382" reactomeId="1861788" points="1671 119, 1701 119, 1741 119" position="1701 119" lineWidth="1.0"> <Inputs> <Input id="2383" points="1633 92" /> <Input id="2384" points="1641 130" /> </Inputs> <Outputs> <Output id="2385" points="1766 120" /> <Output id="2388" points="1773 90" /> </Outputs> <Catalysts> <Catalyst id="2386" points="1701 86" /> </Catalysts> <Properties> <displayName>GBA2 hydrolyzes GlcCer (plasma membrane)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2389" reactomeId="1861789" points="1731 322, 1731 287, 1731 232" position="1731 287" lineWidth="1.0"> <Inputs> <Input id="2390" points="1768 343" /> <Input id="2391" points="1705 353" /> </Inputs> <Outputs> <Output id="2677" points="1691 208" /> <Output id="2385" points="1778 140" /> </Outputs> <Catalysts> <Catalyst id="2393" points="1767 287" /> </Catalysts> <Properties> <displayName>GBA3 hydrolyzes GlcCer (cytosol)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2750" reactomeId="1614362" points="794 1144, 814 1144, 826 1163" position="814 1144" lineWidth="1.0"> <Inputs> <Input id="2751" points="774 1130" /> <Input id="2752" points="778 1158" /> </Inputs> <Outputs> <Output id="2755" points="827 1190" /> <Output id="2753" points="873 1163" /> <Output id="2754" points="872 1134" /> <Output id="27315" points="912 1200" /> </Outputs> <Catalysts> <Catalyst id="2756" points="814 1100" /> </Catalysts> <Inhibitors> <Inhibitor id="3445" points="908 1073" /> </Inhibitors> <Properties> <displayName>SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2857" reactomeId="2248891" points="848 1284, 1040 1465, 1862 1470, 1866 912, 1867 859, 2075 829" position="1866 912" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="2371" /> </Inputs> <Outputs> <Output id="398" /> </Outputs> <Catalysts> <Catalyst id="25966" points="1773 857" /> </Catalysts> <Properties> <displayName>M6PR transports activated ARSA to the lysosome</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="2858" points="834 1255, 829 1225" position="831 1240" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="2371" /> </Inputs> <Outputs> <Output id="2755" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="3104" reactomeId="6785933" points="930 686, 930 709, 912 752" position="930 709" lineWidth="1.0"> <Inputs> <Input id="26644" points="909 678" /> <Input id="46" points="975 619" /> </Inputs> <Outputs> <Output id="27307" points="931 817" /> <Output id="3107" points="749 873, 892 837" /> <Output id="26645" points="935 771" /> </Outputs> <Catalysts> <Catalyst id="26640" points="971 707" /> </Catalysts> <Properties> <displayName>UGT8 transfers Gal from UDP-Gal to CERA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3118" reactomeId="8856223" points="339 1123, 338 1104, 338 1082" position="338 1104" lineWidth="1.0"> <Inputs> <Input id="3119" points="302 1135" /> <Input id="27165" points="358 1135" /> </Inputs> <Outputs> <Output id="3121" points="305 1070" /> <Output id="27162" points="381 1075" /> <Output id="3434" points="414 1117" /> </Outputs> <Catalysts> <Catalyst id="3122" points="325 1103" /> </Catalysts> <Properties> <displayName>B4GALNT1 dimer transfers GalNAc to gangliosides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3429" reactomeId="8878914" points="436 589, 436 571, 435 552" position="436 571" lineWidth="1.0"> <Inputs> <Input id="3430" points="456 597" /> <Input id="3120" points="429 591" /> </Inputs> <Outputs> <Output id="3431" points="462 542" /> <Output id="26653" points="393 559" /> <Output id="27201" points="407 519" /> </Outputs> <Catalysts> <Catalyst id="3432" points="464 571" /> </Catalysts> <Properties> <displayName>B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3435" reactomeId="8959462" points="907 441, 907 461, 906 473" position="907 461" lineWidth="1.0"> <Inputs> <Input id="26513" points="885 430" /> <Input id="26509" points="928 428" /> </Inputs> <Outputs> <Output id="27283" points="745 472" /> <Output id="3438" points="906 485" /> </Outputs> <Catalysts> <Catalyst id="26514" points="940 461" /> </Catalysts> <Properties> <displayName>SAMD8 transfers phosphatidyl from PE onto C16DH CER</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3503" reactomeId="1614336" points="844 1054, 866 1053, 893 1053" position="866 1053" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="2859" points="822 1041" /> <Input id="2756" points="825 1071" /> </Inputs> <Outputs> <Output id="3445" /> </Outputs> <Catalysts> <Catalyst id="2859" points="834 1026, 865 1026" /> </Catalysts> <Properties> <displayName>SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="3505" points="2038 366, 2091 427, 2091 619" position="2091 427" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="3504" /> </Inputs> <Outputs> <Output id="2863" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="3609" reactomeId="9695890" points="1338 769, 1382 787, 1294 1346, 1291 1400" position="1294 1346" lineWidth="1.0"> <Inputs> <Input id="26232" /> </Inputs> <Outputs> <Output id="26551" /> </Outputs> <Catalysts> <Catalyst id="26518" points="1248 1345" /> </Catalysts> <Properties> <displayName>SPNS2,MFSD2B transport S1P from cytosol to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="3616" interactionType="Activate" points="1481 1398, 1460 1405" position="1470 1401" lineWidth="2.0"> <Inputs> <Input id="82" /> </Inputs> <Outputs> <Output id="3615" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableReaction id="3776" reactomeId="9695949" points="1114 733, 1185 731, 1233 731" position="1185 731" lineWidth="1.0"> <Inputs> <Input id="26535" points="1098 730" /> <Input id="26533" points="1055 761" /> </Inputs> <Outputs> <Output id="26232" points="1294 755" /> <Output id="26540" points="1338 726" /> <Output id="26539" points="1306 700" /> </Outputs> <Catalysts> <Catalyst id="3779" points="1183 691" /> </Catalysts> <Inhibitors> <Inhibitor id="3879" points="1295 670" /> </Inhibitors> <Properties> <displayName>SPHK2 phosphorylates sphingoid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3877" reactomeId="9695917" points="1247 636, 1247 637, 1278 641" position="1247 637" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3779" points="1201 662" /> <Input id="3878" points="1318 581" /> </Inputs> <Outputs> <Output id="3879" /> </Outputs> <Properties> <displayName>SPHK2 binds SPHK2 inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3897" reactomeId="9840581" points="2336 94, 2361 118, 2380 137" position="2361 118" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="3898" /> </Inputs> <Outputs> <Output id="3899" /> </Outputs> <Properties> <displayName>GM1 localizes to endosome membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3904" reactomeId="9840579" points="2418 174, 2523 236, 2671 301" position="2523 236" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="3899" /> </Inputs> <Outputs> <Output id="3905" /> </Outputs> <Properties> <displayName>GM1 localizes to ILV membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="3907" interactionType="Activate" points="2220 72, 2297 74" position="2258 73" lineWidth="2.0"> <Inputs> <Input id="3906" /> </Inputs> <Outputs> <Output id="3898" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableReaction id="3968" reactomeId="9840334" points="2798 710, 2746 709, 2717 710" position="2746 709" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="3969" /> </Inputs> <Outputs> <Output id="3970" points="2664 734" /> <Output id="3971" points="2687 779" /> <Output id="3972" points="2777 781" /> <Output id="3973" points="2662 712" /> </Outputs> <Properties> <displayName>PSAP is cleaved</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3974" reactomeId="9840488" points="2597 700, 2571 676, 2550 669" position="2571 676" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3973" stoichiometry="2" /> </Inputs> <Outputs> <Output id="3975" /> </Outputs> <Properties> <displayName>PSAP(195-273) forms a dimer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4036" reactomeId="9840470" points="2592 548, 2536 549, 2526 522" position="2536 549" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="26037" points="2611 557" /> <Input id="26044" points="2641 535" /> </Inputs> <Outputs> <Output id="4040" /> </Outputs> <Catalysts> <Catalyst id="3975" points="2517 626" /> </Catalysts> <Properties> <displayName>PSAP(195-273) dimer:PE binds and mobilizes ligands</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="4823" points="2695 330, 2693 378" position="2694 354" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="3905" /> </Inputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="4829" points="1986 271, 2002 271" position="1994 271" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="152" /> </Inputs> <Outputs> <Output id="4828" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="5328" reactomeId="1605717" points="2616 399, 2598 401, 2599 432" position="2598 401" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="151" points="2607 363" /> <Input id="25724" points="2648 399" /> </Inputs> <Outputs> <Output id="4825" /> </Outputs> <Catalysts> <Catalyst id="151" points="2603 363" /> </Catalysts> <Properties> <displayName>GM2A binds and mobilizes ligands</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="6653" reactomeId="9840795" points="2183 474, 2184 501, 2184 521" position="2184 501" lineWidth="1.0"> <Inputs> <Input id="6654" points="2183 439" /> <Input id="276" points="2234 454" /> </Inputs> <Outputs> <Output id="6656" points="2184 547" /> <Output id="6718" points="2244 540" /> </Outputs> <Catalysts> <Catalyst id="16586" points="2151 501" /> </Catalysts> <Properties> <displayName>Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="7686" reactomeId="9840833" points="2184 612, 2184 635, 2183 658" position="2184 635" lineWidth="1.0"> <Inputs> <Input id="6656" points="2184 576" /> <Input id="7687" points="2235 595" /> </Inputs> <Outputs> <Output id="7688" points="2182 686" /> <Output id="7750" points="2230 673" /> </Outputs> <Catalysts> <Catalyst id="2863" points="2143 635" /> </Catalysts> <Properties> <displayName>bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="25710" reactomeId="9840884" points="2411 376, 2411 402, 2409 434" position="2411 402" lineWidth="1.0"> <Inputs> <Input id="25712" points="2411 334" /> <Input id="4827" points="2305 339" /> </Inputs> <Outputs> <Output id="151" points="2587 363, 2440 455" /> <Output id="25740" points="2409 493" /> <Output id="25720" points="2369 462" /> </Outputs> <Catalysts> <Catalyst id="25714" points="2375 405" /> </Catalysts> <Activators> <Activator id="25718" points="2671 466, 2524 469" /> </Activators> <Properties> <displayName>bHEXA,bHEXS hydrolyze GM2A:SM2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="25715" points="2057 355, 2272 399" position="2164 377" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="3504" /> </Inputs> <Outputs> <Output id="25714" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="25725" points="2696 330, 2697 384" position="2696 357" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="3905" /> </Inputs> <Outputs> <Output id="25724" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="25739" reactomeId="9840949" points="2410 567, 2410 585, 2411 606" position="2410 585" lineWidth="1.0"> <Inputs> <Input id="25740" points="2410 530" /> <Input id="25741" points="2389 552" /> </Inputs> <Outputs> <Output id="282" points="2411 666" /> <Output id="25743" points="2386 616" /> </Outputs> <Catalysts> <Catalyst id="25745" points="2397 585" /> </Catalysts> <Properties> <displayName>ARSA removes sulfate from SM3</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="25763" points="2126 724, 2166 730, 2326 728" position="2166 730" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="6963" /> </Inputs> <Outputs> <Output id="25762" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="25951" reactomeId="9841189" points="2022 1144, 2051 1143, 2079 1143" position="2051 1143" lineWidth="1.0"> <Inputs> <Input id="25952" points="2006 1150" /> <Input id="25748" points="1954 1079" /> </Inputs> <Outputs> <Output id="359" points="2192 1021" /> <Output id="25958" points="2126 1182" /> <Output id="25960" points="2152 1151" /> <Output id="25962" points="2187 1112" /> </Outputs> <Catalysts> <Catalyst id="25955" points="2051 1183" /> </Catalysts> <Properties> <displayName>GLA hydrolyzes PSAP(195-273):Gal2Cer:PE</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="26039" reactomeId="9842115" points="2598 630, 2579 597, 2599 589" position="2579 597" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3975" points="2568 636" /> <Input id="25722" points="2649 639" /> </Inputs> <Outputs> <Output id="26037" /> </Outputs> <Catalysts> <Catalyst id="3975" points="2537 626" /> </Catalysts> <Properties> <displayName>PSAP(195-273) dimer binds PE</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="26045" points="2714 330, 2771 375, 2770 489, 2736 500" position="2770 432" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="3905" /> </Inputs> <Outputs> <Output id="26044" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="26541" reactomeId="9843721" points="1453 1344, 1454 1343, 1456 1345" position="1454 1343" lineWidth="1.0"> <Inputs> <Input id="26542" points="1427 1281" /> <Input id="66" points="1425 758" /> <Input id="26543" points="1421 1317" /> </Inputs> <Outputs> <Output id="26544" points="1513 1275" /> <Output id="82" points="1496 1371" /> <Output id="26547" points="1482 1246" /> <Output id="26550" points="1543 1297" /> </Outputs> <Catalysts> <Catalyst id="26545" points="1424 1342" /> </Catalysts> <Properties> <displayName>ABCC1,ABCG2 transport C18-S1P to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="26553" interactionType="Activate" points="1313 1418, 1341 1419" position="1327 1418" lineWidth="2.0"> <Inputs> <Input id="26551" /> </Inputs> <Outputs> <Output id="3615" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.EntitySetAndMemberLink id="26596" points="1425 721, 1437 471, 1270 386" position="1437 471" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="66" /> </Inputs> <Outputs> <Output id="26594" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="26598" points="1432 221, 1313 203" position="1372 212" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="74" /> </Inputs> <Outputs> <Output id="26597" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="26599" points="1194 173, 1228 180" position="1211 176" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="70" /> </Inputs> <Outputs> <Output id="26597" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="26650" reactomeId="9844587" points="354 384, 353 401, 342 429" position="353 401" lineWidth="1.0"> <Inputs> <Input id="26652" points="359 383" /> <Input id="27138" points="312 375" /> </Inputs> <Outputs> <Output id="26657" points="357 434" /> <Output id="27142" points="316 434" /> <Output id="26653" points="368 545" /> </Outputs> <Catalysts> <Catalyst id="26656" points="319 401" /> </Catalysts> <Properties> <displayName>GAL3ST1 transfers sulfate to GalCer,LacCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="26710" reactomeId="9844860" points="363 276, 363 257, 363 238" position="363 257" lineWidth="1.0"> <Inputs> <Input id="26711" points="373 277" /> <Input id="26712" points="342 277" /> </Inputs> <Outputs> <Output id="26714" points="318 229" /> <Output id="26715" points="387 228" /> <Output id="26718" points="354 200" /> </Outputs> <Catalysts> <Catalyst id="26716" points="309 257" /> </Catalysts> <Properties> <displayName>ST3GAL5 transfers NeuNAc to ceramides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndEntitySetLink id="27156" points="270 1070, 265 1135" position="267 1102" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="3121" /> </Inputs> <Outputs> <Output id="3119" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.RenderableReaction id="27173" reactomeId="9845516" points="343 971, 343 954, 343 937" position="343 954" lineWidth="1.0"> <Inputs> <Input id="27174" points="304 975" /> <Input id="27183" points="345 989" /> </Inputs> <Outputs> <Output id="27177" points="287 917" /> <Output id="1243" points="377 961" /> <Output id="27181" points="412 942" /> </Outputs> <Catalysts> <Catalyst id="27179" points="314 950" /> </Catalysts> <Properties> <displayName>B3GALT4 transfers Gal to gangliosides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndEntitySetLink id="27176" points="260 1010, 265 1021" position="262 1015" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="27174" /> </Inputs> <Outputs> <Output id="3121" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.RenderableReaction id="27190" reactomeId="9845538" points="358 873, 358 853, 358 819" position="358 853" lineWidth="1.0"> <Inputs> <Input id="27177" points="305 882" /> <Input id="27197" points="378 885" /> </Inputs> <Outputs> <Output id="27191" points="331 813" /> <Output id="27195" points="374 813" /> <Output id="27199" points="386 778" /> </Outputs> <Catalysts> <Catalyst id="27192" points="322 850" /> </Catalysts> <Properties> <displayName>ST3GAL2,3 transfer Neu5Ac to gangliosides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27222" reactomeId="9845587" points="436 842, 434 821, 434 798" position="434 821" lineWidth="1.0"> <Inputs> <Input id="27223" points="454 850" /> <Input id="27197" points="409 885" /> </Inputs> <Outputs> <Output id="27225" points="475 786" /> <Output id="27195" points="416 803" /> <Output id="27199" points="411 778" /> </Outputs> <Catalysts> <Catalyst id="27227" points="461 817" /> </Catalysts> <Properties> <displayName>ST8SIA5 transfers Neu5Ac to gangliosides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndEntitySetLink id="27224" points="454 856, 306 821" position="380 838" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="27223" /> </Inputs> <Outputs> <Output id="27191" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.RenderableReaction id="27230" reactomeId="428231" points="1052 639, 1053 668, 1052 693" position="1053 668" lineWidth="1.0"> <Inputs> <Input id="27231" points="1068 628" /> <Input id="46" points="1013 614" /> </Inputs> <Outputs> <Output id="26533" points="1035 753" /> <Output id="26580" points="1081 690" /> </Outputs> <Catalysts> <Catalyst id="55" points="1019 667" /> </Catalysts> <Properties> <displayName>ACER1 hydrolyzes ceramide (endoplasmic reticulum)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27232" reactomeId="428205" points="576 931, 576 905, 575 877" position="576 905" lineWidth="1.0"> <Inputs> <Input id="102" points="523 969" /> <Input id="25988" points="583 935" /> </Inputs> <Outputs> <Output id="26582" points="598 868" /> <Output id="26593" points="573 840" /> </Outputs> <Catalysts> <Catalyst id="107" points="526 914" /> </Catalysts> <Properties> <displayName>ACER2 hydrolyzes ceramide (Golgi)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27240" reactomeId="428262" points="655 668, 656 691, 657 721" position="656 691" lineWidth="1.0"> <Inputs> <Input id="26574" points="683 660" /> <Input id="3442" points="632 651" /> </Inputs> <Outputs> <Output id="40" points="630 715" /> <Output id="26582" points="633 842" /> </Outputs> <Catalysts> <Catalyst id="26578" points="679 690" /> </Catalysts> <Properties> <displayName>ACER3 hydrolyzes phytoceramide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27244" reactomeId="428664" points="1279 845, 1061 836, 1054 818" position="1061 836" lineWidth="1.0"> <Inputs> <Input id="26232" points="1309 782" /> <Input id="26589" points="1297 851" /> </Inputs> <Outputs> <Output id="78" points="1026 808" /> <Output id="26533" points="1039 790" /> </Outputs> <Catalysts> <Catalyst id="90" points="1012 837" /> </Catalysts> <Properties> <displayName>SGPP1,2 dephosphorylate sphingoid-1-phosphates</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27247" reactomeId="428681" points="1249 351, 1249 288, 1272 254" position="1249 288" lineWidth="1.0"> <Inputs> <Input id="26594" /> </Inputs> <Outputs> <Output id="69" points="1302 241" /> <Output id="26597" points="1262 215" /> </Outputs> <Catalysts> <Catalyst id="71" points="1028 289" /> </Catalysts> <Properties> <displayName>PXLP-SGPL1 cleaves sphingoid-1-phosphates</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27248" reactomeId="428696" points="1573 1180, 1596 1180, 1613 1181" position="1596 1180" lineWidth="1.0"> <Inputs> <Input id="27249" points="1554 1186" /> <Input id="66" points="1430 758" /> </Inputs> <Outputs> <Output id="26612" points="1625 1184" /> <Output id="27251" points="1630 1163" /> </Outputs> <Catalysts> <Catalyst id="79" points="1604 1318" /> </Catalysts> <Properties> <displayName>PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27253" reactomeId="428690" points="1576 1389, 1599 1382, 1646 1380" position="1599 1382" lineWidth="1.0"> <Inputs> <Input id="82" points="1556 1389" /> <Input id="81" points="1572 1406" /> </Inputs> <Outputs> <Output id="83" points="1662 1403" /> <Output id="26612" points="1657 1221" /> </Outputs> <Catalysts> <Catalyst id="85" points="1546 1353" /> </Catalysts> <Properties> <displayName>PLPP1 dephosphorylates extracellular sphingosine-1-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27256" reactomeId="5692261" points="1478 305, 1477 333, 1476 360" position="1477 333" lineWidth="1.0"> <Inputs> <Input id="2938" points="1417 268" /> <Input id="74" points="1469 246" /> <Input id="2940" points="1517 265" /> </Inputs> <Outputs> <Output id="2941" points="1556 393" /> <Output id="2942" points="1477 400" /> <Output id="2946" points="1456 366" /> </Outputs> <Catalysts> <Catalyst id="3117" points="1046 335" /> </Catalysts> <Properties> <displayName>ALDH3A2-1 oxidises HD2NAL to PALM</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27258" reactomeId="5696080" points="1224 138, 1255 137, 1282 137" position="1255 137" lineWidth="1.0"> <Inputs> <Input id="70" points="1194 156" /> <Input id="2948" points="1198 122" /> <Input id="2956" points="1146 134" /> </Inputs> <Outputs> <Output id="2941" points="1583 385, 1586 158" /> <Output id="2952" points="1318 120" /> <Output id="2954" points="1334 160" /> </Outputs> <Catalysts> <Catalyst id="2950" points="1255 85" /> </Catalysts> <Properties> <displayName>ALDH3B1 oxidises HXAL to PALM</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27261" reactomeId="6808464" points="1764 462, 1762 480, 1763 544" position="1762 480" lineWidth="1.0"> <Inputs> <Input id="3114" points="1761 444" /> <Input id="27262" points="1830 469" /> <Input id="27266" points="1825 436" /> </Inputs> <Outputs> <Output id="3115" points="1764 564" /> <Output id="2942" points="1499 437, 1612 514" /> <Output id="27264" points="1725 554" /> </Outputs> <Catalysts> <Catalyst id="3116" points="1679 479" /> </Catalysts> <Properties> <displayName>ALDH3B2 oxidises HXAL to PALM</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27323" reactomeId="9846305" points="456 201, 454 180, 433 177" position="454 180" lineWidth="1.0"> <Inputs> <Input id="26711" points="429 266" /> <Input id="27324" points="471 200" /> </Inputs> <Outputs> <Output id="26715" points="418 203" /> <Output id="27325" points="416 166" /> <Output id="26718" points="372 180" /> </Outputs> <Catalysts> <Catalyst id="27326" points="491 167" /> </Catalysts> <Properties> <displayName>ST6GALNAC5,6 transfer Neu5Ac to GM1b</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27333" reactomeId="9846332" points="333 723, 334 699, 334 678" position="334 699" lineWidth="1.0"> <Inputs> <Input id="27334" points="288 741" /> <Input id="27336" points="334 731" /> </Inputs> <Outputs> <Output id="27337" points="311 671" /> <Output id="27338" points="326 635" /> <Output id="26653" points="366 582" /> </Outputs> <Catalysts> <Catalyst id="27370" points="296 705" /> </Catalysts> <Properties> <displayName>FUT1,2 transfer fucose to gangliosides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndEntitySetLink id="27335" points="266 776, 264 882" position="265 829" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="27334" /> </Inputs> <Outputs> <Output id="27177" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.RenderableReaction id="27347" reactomeId="9846477" points="445 684, 444 664, 443 650" position="444 664" lineWidth="1.0"> <Inputs> <Input id="27350" points="460 691" /> <Input id="27352" points="427 698" /> </Inputs> <Outputs> <Output id="3430" points="472 627" /> <Output id="26653" points="368 582, 355 632" /> <Output id="27354" points="406 655" /> </Outputs> <Catalysts> <Catalyst id="27348" points="470 661" /> </Catalysts> <Properties> <displayName>A4GALT transfers galactose to LacCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27359" reactomeId="9846501" points="441 400, 437 388, 438 371" position="437 388" lineWidth="1.0"> <Inputs> <Input id="27371" points="440 416" /> <Input id="27365" points="478 411" /> </Inputs> <Outputs> <Output id="27361" points="482 333" /> <Output id="27367" points="407 343" /> <Output id="27369" points="436 355" /> </Outputs> <Catalysts> <Catalyst id="27362" points="473 386" /> </Catalysts> <Properties> <displayName>B3GNT5 transfers GlcNAc to LacCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27407" reactomeId="5693761" points="1042 204, 1044 190, 1045 176" position="1044 190" lineWidth="1.0"> <Inputs> <Input id="26335" points="1072 232" /> <Input id="26350" stoichiometry="2" points="1142 220" /> <Input id="26348" points="1070 191" /> <Input id="26344" stoichiometry="2" points="1000 227" /> </Inputs> <Outputs> <Output id="26336" points="1068 122" /> <Output id="26337" points="1011 127" /> <Output id="26346" stoichiometry="2" points="920 152" /> </Outputs> <Catalysts> <Catalyst id="3096" points="1008 190" /> </Catalysts> <Properties> <displayName>FA2H hydroxylates 1,2-saturated fatty acids</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27417" reactomeId="9851347" points="401 1245, 372 1244, 340 1243" position="372 1244" lineWidth="1.0"> <Inputs> <Input id="26993" points="426 1216" /> <Input id="2102" points="468 1247" /> </Inputs> <Outputs> <Output id="26994" points="316 1234" /> <Output id="26997" points="326 1254" /> <Output id="26999" points="340 1221" /> </Outputs> <Catalysts> <Catalyst id="26995" points="373 1294" /> </Catalysts> <Properties> <displayName>B4GALT5/6 transfer Gal to GlcCer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="27419" interactionType="Activate" points="529 1257, 551 1266" position="540 1261" lineWidth="2.0"> <Inputs> <Input id="2102" /> </Inputs> <Outputs> <Output id="27418" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableInteraction id="27420" interactionType="Activate" points="708 900, 620 1043, 619 1262" position="620 1043" lineWidth="2.0"> <Inputs> <Input id="3107" /> </Inputs> <Outputs> <Output id="27418" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableReaction id="27421" reactomeId="428676" points="1424 721, 1411 485, 1411 316" position="1411 485" lineWidth="1.0"> <Inputs> <Input id="66" /> </Inputs> <Outputs> <Output id="69" points="1343 251" /> <Output id="74" points="1458 246" /> </Outputs> <Catalysts> <Catalyst id="71" points="1010 305" /> </Catalysts> <Properties> <displayName>sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27427" reactomeId="429730" points="985 1140, 986 1089, 985 997" position="986 1089" lineWidth="1.0"> <Inputs> <Input id="27428" stoichiometry="3" points="1013 1167" /> <Input id="110" points="986 1237" /> <Input id="120" points="1131 1247, 1051 1152" /> </Inputs> <Outputs> <Output id="99" points="779 1001" /> <Output id="126" stoichiometry="3" points="1023 964" /> </Outputs> <Catalysts> <Catalyst id="110" points="983 1237, 955 1089" /> </Catalysts> <Properties> <displayName>PPM1L dephosphorylates multiphospho-CERT1-2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27438" reactomeId="9956909" points="957 936, 721 941, 603 989, 531 987" position="721 941" lineWidth="1.0"> <Inputs> <Input id="26642" /> </Inputs> <Outputs> <Output id="102" /> </Outputs> <Catalysts> <Catalyst id="99" points="721 982" /> </Catalysts> <Activators> <Activator id="103" points="652 913" /> </Activators> <Properties> <displayName>CERT1-2 transfers CERA from the ER membrane to the Golgi membrane</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
width	2912
[Change default viewing format]

No pathways have been reviewed or authored by Diagram of Sphingolipid metabolism (554229)