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Details on Person UniProt:P19086 GNAZ
| Class:Id | ReferenceGeneProduct:55372 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-355 added on Sat February 7 2015;initiator methionine:1 for 55372 removed on Fri Nov 03 2023;initiator methionine: for 55372 added on Fri Nov 03 2023;initiator methionine: for 55372 removed on Fri Aug 15 2025;initiator methionine:1 for 55372 added on Fri Aug 15 2025 |
| _displayName | UniProt:P19086 GNAZ |
| _timestamp | 2025-08-15 21:22:54 |
| chain | initiator methionine:1 chain:2-355 |
| checksum | E868FAE7CD2873EB |
| comment | FUNCTION Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.SUBUNIT G-proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with ADGRB2 (PubMed:28891236).SUBCELLULAR LOCATION Belongs to the G-alpha family. G(i/o/t/z) subfamily. |
| description | recommendedName: Guanine nucleotide-binding protein G(z) subunit alpha alternativeName: G(x) alpha chain alternativeName: Gz-alpha |
| geneName | GNAZ |
| identifier | P19086 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure ADP-ribosylation GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Palmitate Proteomics identification Reference proteome Transducer |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | GNAZ |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996593] ENSEMBL:ENSG00000128266 GNAZ [Homo sapiens] |
| secondaryIdentifier | GNAZ_HUMAN B2R6C1 Q4QRJ6 |
| sequenceLength | 355 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:167416] GNAZ [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:391955] GNAZ [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:804942] p-S27-GNAZ [plasma membrane] [Homo sapiens] |
| (referenceSequence) | [ModifiedResidue:804923] O-phospho-L-serine at 27 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P19086 GNAZ (55372)
