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Details on Person UniProt:Q9P2B2 PTGFRN
| Class:Id | ReferenceGeneProduct:54972 |
|---|---|
| _chainChangeLog | signal peptide:1-25 added on Fri February 6 2015;chain:26-879 added on Fri February 6 2015 |
| _displayName | UniProt:Q9P2B2 PTGFRN |
| _timestamp | 2024-11-03 20:00:56 |
| chain | signal peptide:1-25 chain:26-879 |
| checksum | 9712C398A74DF570 |
| comment | FUNCTION Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).SUBUNIT Interacts with CD9 and CD81 (PubMed:11278880). Part of a complex composed of CD9, CD81 and IGSF8 (By similarity). Also seems to interact with CD63, CD82 and CD151 (PubMed:11278880).INTERACTION Truncated C-terminus. |
| description | recommendedName: Prostaglandin F2 receptor negative regulator alternativeName: CD9 partner 1 shortName: CD9P-1 alternativeName: Glu-Trp-Ile EWI motif-containing protein F shortName: EWI-F alternativeName: Prostaglandin F2-alpha receptor regulatory protein alternativeName: Prostaglandin F2-alpha receptor-associated protein cdAntigenNameCD315/cdAntigenName |
| geneName | PTGFRN CD9P1 EWIF FPRP KIAA1436 |
| identifier | Q9P2B2 |
| isSequenceChanged | FALSE |
| keyword | Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Golgi apparatus Immunoglobulin domain Membrane Phosphoprotein Proteomics identification Reference proteome Repeat Signal Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PTGFRN |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962100] ENSEMBL:ENSG00000134247 PTGFRN [Homo sapiens] |
| secondaryIdentifier | FPRP_HUMAN Q5VVU9 Q8N2K6 |
| sequenceLength | 879 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:197827] PTGFRN [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9P2B2 PTGFRN (54972)
