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Details on Person mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

Class:IdLiteratureReference:549540
_displayNamemCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
_timestamp2010-03-21 04:33:05
author[Person:549526] Kume, K
[Person:508682] Zylka, MJ
[Person:549406] Sriram, S
[Person:508624] Shearman, LP
[Person:400406] Weaver, DR
[Person:418944] Jin, X
[Person:400302] Maywood, ES
[Person:400378] Hastings, MH
[Person:400367] Reppert, SM
created[InstanceEdit:549380] May, B, 2010-03-21
journalCell
pages193-205
pubMedIdentifier10428031
titlemCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
volume98
year1999
(literatureReference)[BlackBoxEvent:1856952] Formation of Cry:Per:Kinase complex [Mus musculus]
[Reaction:5663146] p-Bmal1:p-Clock,Npas2 binds Cry1 gene [Mus musculus]
[BlackBoxEvent:9909360] Formation of Cry:Per:Kinase complex [Mus musculus]
[BlackBoxEvent:9909538] Phosphorylated Cry:Per:Csnk1d,e complex translocates from the cytosol to the nucleus [Mus musculus]
[BlackBoxEvent:9926580] Phosphorylated Bmal1:Clock and coactivators positively regulate expression of Cry2 [Mus musculus]
[Pathway:9931530] Phosphorylation and nuclear translocation of the CRY:PER:kinase complex [Homo sapiens]
[RegulationReference:9642643] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Cry1 gene [nucleoplasm]' mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
[Complex:508609] p-Cry:p-Per:Kinase [cytosol] [Mus musculus]
[Complex:508679] Cry:Per:Kinase [cytosol] [Mus musculus]
[Complex:508739] p-Cry:p-Per:Kinase [nucleoplasm] [Mus musculus]
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