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Details on Person Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
| Class:Id | LiteratureReference:549497 |
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| _displayName | Rhythmic histone acetylation underlies transcription in the mammalian circadian clock |
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| _timestamp | 2010-03-21 04:31:00 |
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| author | [Person:421286] Etchegaray, JP
[Person:200246] Lee, C
[Person:549397] Wade, PA
[Person:400367] Reppert, SM |
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| created | [InstanceEdit:549380] May, B, 2010-03-21 |
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| journal | Nature |
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| pages | 177-82 |
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| pubMedIdentifier | 12483227 |
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| title | Rhythmic histone acetylation underlies transcription in the mammalian circadian clock |
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| volume | 421 |
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| year | 2003 |
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| (literatureReference) | [Reaction:5663146] p-Bmal1:p-Clock,Npas2 binds Cry1 gene [Mus musculus]
[BlackBoxEvent:9909564] Phosphorylated Bmal1:Clock,Npas2 and coactivators positively regulate expression of Period-1 (Per1) [Mus musculus]
[BlackBoxEvent:9926584] Phosphorylated Bmal1:Clock and coactivators positively regulate expression of Cry1 [Mus musculus]
[Reaction:9926600] p-S97-Bmal1:p-T451,T461-Clock,p-Npas2 and coactivators bind the Cry1 gene [Mus musculus]
[Complex:9926602] p-S97-Bmal1:p-T451,T461-Clock:Kmt2a:Cry1 gene [nucleoplasm] [Mus musculus]
[Complex:9933424] p-S97-Bmal1:p-T451,T461-Clock,p-Npas2:Kmt2a:Cry1 gene [nucleoplasm] [Mus musculus]
[RegulationReference:9641211] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Per1 gene [nucleoplasm]' CK2alpha phosphorylates BMAL1 to regulate the mammalian clock
[RegulationReference:9642643] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Cry1 gene [nucleoplasm]' mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
[RegulationReference:9926609] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock,p-Npas2:Crebbp:Kmt2a:Per1 gene [nucleoplasm]' CK2alpha phosphorylates BMAL1 to regulate the mammalian clock |
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