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Details on Person Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation
| Class:Id | LiteratureReference:549485 |
| _displayName | Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation |
| _timestamp | 2010-03-21 04:30:26 |
| author | [Person:421282] Kondratov, RV [Person:549436] Shamanna, RK [Person:421279] Kondratova, AA [Person:421297] Gorbacheva, VY [Person:421288] Antoch, MP |
| created | [InstanceEdit:549380] May, B, 2010-03-21 |
| journal | FASEB J |
| pages | 530-2 |
| pubMedIdentifier | 16507766 |
| title | Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation |
| volume | 20 |
| year | 2006 |
| (literatureReference) | [RegulationReference:9641211] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Per1 gene [nucleoplasm]' CK2alpha phosphorylates BMAL1 to regulate the mammalian clock [RegulationReference:9642643] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Cry1 gene [nucleoplasm]' mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop [RegulationReference:9926589] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock,p-Npas2:Kmt2a:Cry1 gene [nucleoplasm]' Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation [RegulationReference:9926609] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock,p-Npas2:Crebbp:Kmt2a:Per1 gene [nucleoplasm]' CK2alpha phosphorylates BMAL1 to regulate the mammalian clock [Reaction:5663146] p-Bmal1:p-Clock,Npas2 binds Cry1 gene [Mus musculus] [BlackBoxEvent:9909564] Phosphorylated Bmal1:Clock,Npas2 and coactivators positively regulate expression of Period-1 (Per1) [Mus musculus] [BlackBoxEvent:9926584] Phosphorylated Bmal1:Clock and coactivators positively regulate expression of Cry1 [Mus musculus] |
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