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Details on Person Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation

Class:IdLiteratureReference:549485
_displayNameDual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation
_timestamp2010-03-21 04:30:26
author[Person:421282] Kondratov, RV
[Person:549436] Shamanna, RK
[Person:421279] Kondratova, AA
[Person:421297] Gorbacheva, VY
[Person:421288] Antoch, MP
created[InstanceEdit:549380] May, B, 2010-03-21
journalFASEB J
pages530-2
pubMedIdentifier16507766
titleDual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation
volume20
year2006
(literatureReference)[RegulationReference:9641211] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Per1 gene [nucleoplasm]' CK2alpha phosphorylates BMAL1 to regulate the mammalian clock
[RegulationReference:9642643] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Cry1 gene [nucleoplasm]' mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
[RegulationReference:9926589] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock,p-Npas2:Kmt2a:Cry1 gene [nucleoplasm]' Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation
[RegulationReference:9926609] Positive gene expression regulation by 'p-S97-Bmal1:p-T451,T461-Clock,p-Npas2:Crebbp:Kmt2a:Per1 gene [nucleoplasm]' CK2alpha phosphorylates BMAL1 to regulate the mammalian clock
[Reaction:5663146] p-Bmal1:p-Clock,Npas2 binds Cry1 gene [Mus musculus]
[BlackBoxEvent:9909564] Phosphorylated Bmal1:Clock,Npas2 and coactivators positively regulate expression of Period-1 (Per1) [Mus musculus]
[BlackBoxEvent:9926584] Phosphorylated Bmal1:Clock and coactivators positively regulate expression of Cry1 [Mus musculus]
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