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Details on Person Cry proteins stabilize unphosphorylated Bmal1:Clock,Npas2

Class:Id	Reaction:549451
_displayName	Cry proteins stabilize unphosphorylated Bmal1:Clock,Npas2
_doRelease	TRUE
_timestamp	2025-02-28 01:56:36
authored	[InstanceEdit:549443] May, B, 2010-03-19
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:549380] May, B, 2010-03-21
edited	[InstanceEdit:549443] May, B, 2010-03-19
input	[DefinedSet:508675] Cry1,Cry2 [cytosol] [Mus musculus] [Complex:508648] Bmal1:Clock,Npas2 [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:421285] Post-translational regulation of circadian transcriptional CLOCK(NPAS2)/BMAL1 complex by CRYPTOCHROMES [LiteratureReference:400260] Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression
modified	[InstanceEdit:766127] May, B, 2010-05-21 [InstanceEdit:847704] May, B, 2010-05-30 [InstanceEdit:879757] May, B, 2010-06-23 [InstanceEdit:927716] May, B, 2010-08-06 [InstanceEdit:5252142] May, B, 2014-02-05 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9938718] May, Bruce, 2025-02-19 [InstanceEdit:9939539] May, Bruce, 2025-02-28 [InstanceEdit:9939559] May, Bruce, 2025-02-28
name	Cry proteins stabilize unphosphorylated Bmal1:Clock,Npas2
output	[Complex:549343] Bmal1:Clock,Npas2:Cry [cytosol] [Mus musculus]
releaseDate	2010-09-21
reviewed	[InstanceEdit:879756] Albrecht, Urs, 2010-06-23 [InstanceEdit:879786] Delaunay, F, 2010-06-23 [InstanceEdit:879790] Hirota, T, 2010-06-23 [InstanceEdit:879726] Kay, SA, 2010-06-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1105335] R-MMU-549451.3
summation	[Summation:549509] Cry1 and Cry2 bind unphosphorylated Bmal1:Clock/Npas2 (Arntl...
(inferredFrom)	[Reaction:549355] CRY proteins stabilize unphosphorylated BMAL1:CLOCK,NPAS2 [Homo sapiens]
(replacementInstances)	[_Deleted:9032440] Deletion of instance: 5334727 [_Deleted:9032442] Deletion of instance: 508751
(updatedInstance)	[_UpdateTracker:9787155] Update Tracker - [Reaction:549451] Cry proteins stabilize unphosphorylated Bmal1:Clock,Npas2 - v46:[modifyText]
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No pathways have been reviewed or authored by Cry proteins stabilize unphosphorylated Bmal1:Clock,Npas2 (549451)