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Details on Person Expression of FACTOR VII (F7)

Class:Id	BlackBoxEvent:549428
_displayName	Expression of FACTOR VII (F7)
_doRelease	TRUE
_timestamp	2025-03-06 22:55:07
authored	[InstanceEdit:549443] May, B, 2010-03-19
compartment	[Compartment:7660] nucleoplasm [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:549380] May, B, 2010-03-21
edited	[InstanceEdit:549443] May, B, 2010-03-19
inferredFrom	[BlackBoxEvent:549502] Expression of Coagulation Factor VII (F7) [Mus musculus]
input	[EntityWithAccessionedSequence:5641222] F7 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:549398] Liver-specific expression of the human factor VII gene
modified	[InstanceEdit:766127] May, B, 2010-05-21 [InstanceEdit:847704] May, B, 2010-05-30 [InstanceEdit:879757] May, B, 2010-06-23 [InstanceEdit:927716] May, B, 2010-08-06 [InstanceEdit:983112] May, B, 2010-10-29 [InstanceEdit:5641233] May, Bruce, 2014-11-16 [InstanceEdit:5663195] May, Bruce, 2015-01-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626992] May, Bruce, 2018-10-31 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9940986] May, Bruce, 2025-03-06
name	Expression of FACTOR VII (F7)
output	[EntityWithAccessionedSequence:159848] F7(21-466) [endoplasmic reticulum lumen] [Homo sapiens]
precedingEvent	[Reaction:5663127] p-S90-BMAL1:p-T451,T461-CLOCK,NPAS2 binds F7 gene [Homo sapiens] [BlackBoxEvent:9920665] p-S90-BMAL1:p-T451,T461-CLOCK translocates from the cytosol to the nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:549592] Positive gene expression regulation by 'p-S90-BMAL1:p-T451,T461-CLOCK,NPAS2:F7 gene [nucleoplasm]'
releaseDate	2010-09-21
reviewed	[InstanceEdit:422151] D'Eustachio, P, 2009-05-26 22:13:22 [InstanceEdit:879756] Albrecht, Urs, 2010-06-23 [InstanceEdit:879726] Kay, SA, 2010-06-23 [InstanceEdit:879790] Hirota, T, 2010-06-23 [InstanceEdit:879786] Delaunay, F, 2010-06-23 [InstanceEdit:9940981] Albrecht, Urs, 2025-03-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104738] R-HSA-549428.6
summation	[Summation:549476] The FACTOR VII (F7) gene is transcribed to yield mRNA and th... [Summation:549584] Activation of FACTOR VII expression by phosphorylated BMAL1:...
(hasEvent)	[Pathway:1368108] BMAL1:CLOCK,NPAS2 activates circadian expression [Homo sapiens]
(precedingEvent)	[Reaction:159761] GGCX gamma-carboxylates F7(21-466) (pro-factor VII) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776044] Update Tracker - [BlackBoxEvent:549428] Expression of FACTOR VII (F7) - v78:[addSummation, modifyText] [_UpdateTracker:9785408] Update Tracker - [BlackBoxEvent:549428] Expression of FACTOR VII (F7) - v52:[add_removeRegulator] [_UpdateTracker:9785582] Update Tracker - [BlackBoxEvent:549428] Expression of FACTOR VII (F7) - v51:[addInput] [_UpdateTracker:9787047] Update Tracker - [BlackBoxEvent:549428] Expression of FACTOR VII (F7) - v46:[modifyText]
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No pathways have been reviewed or authored by Expression of FACTOR VII (F7) (549428)