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Details on Person 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]

Class:Id	Reaction:549192
_displayName	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]
_doRelease	TRUE
_timestamp	2016-11-10 00:54:34
catalystActivity	[CatalystActivity:549191] diacylglycerol O-acyltransferase activity of DGAT2 [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9643744] diacylglycerol O-acyltransferase activity of DGAT2 [endoplasmic reticulum membrane] Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:549172] D'Eustachio, P, 2010-03-17
input	[SimpleEntity:76103] DAG [cytosol] [SimpleEntity:75967] FACoA [cytosol]
literatureReference	[LiteratureReference:549174] Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members [LiteratureReference:549189] A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice
modified	[InstanceEdit:549196] D'Eustachio, P, 2010-03-17 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] Conversion of Diacylglycerol to Triacylglycerol [DGAT2]
output	[SimpleEntity:549167] TAG [cytosol] [SimpleEntity:76194] CoA-SH [cytosol]
precedingEvent	[Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate [Homo sapiens] [Reaction:75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) [Homo sapiens]
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104193] R-HSA-549192.4
summation	[Summation:549194] Diacylglycerol O-acyltransferase 1 (DGAT2) associated with t...
(hasEvent)	[Pathway:75109] Triglyceride biosynthesis [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9789005] Update Tracker - [Reaction:549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - v39:[modifyText]
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No pathways have been reviewed or authored by 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (549192)