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Details on Person Diagram of Asparagine N-linked glycosylation, Defective ALG1 causes CDG-1k, Defective ALG11 causes CDG-1p, Defective ALG2 causes CDG-1i, Defective DPAGT1 causes CDG-1j, CMSTA2, Defective GFPT1 causes CMSTA1, Defective MPI causes MPI-CDG, Defective PMM2 causes PMM2-CDG, Defective ALG12 causes CDG-1g, Defective ALG3 causes CDG-1d, Defective ALG6 causes CDG-1c, Defective ALG8 causes CDG-1h, Defective ALG9 causes CDG-1l, Defective DPM1 causes DPM1-CDG, Defective DPM2 causes DPM2-CDG, Defective DPM3 causes DPM3-CDG, Defective MPDU1 causes CDG-1f, Defective RFT1 causes CDG-1n, Defective DHDDS causes RP59, Defective DOLK causes DOLK-CDG, Defective SRD5A3 causes SRD5A3-CDG, KHRZ, Defective B4GALT1 causes CDG-2d, Defective MAN1B1 causes MRT15, Defective MGAT2 causes CDG-2a, Defective MOGS causes CDG-2b, and Defective ALG14 causes ALG14-CMS
| Class:Id | PathwayDiagram:548980 |
|---|---|
| _displayName | Diagram of Asparagine N-linked glycosylation, Defective ALG1 causes CDG-1k, Defective ALG11 causes CDG-1p, Defective ALG2 causes CDG-1i, Defective DPAGT1 causes CDG-1j, CMSTA2, Defective GFPT1 causes CMSTA1, Defective MPI causes MPI-CDG, Defective PMM2 causes PMM2-CDG, Defective ALG12 causes CDG-1g, Defective ALG3 causes CDG-1d, Defective ALG6 causes CDG-1c, Defective ALG8 causes CDG-1h, Defective ALG9 causes CDG-1l, Defective DPM1 causes DPM1-CDG, Defective DPM2 causes DPM2-CDG, Defective DPM3 causes DPM3-CDG, Defective MPDU1 causes CDG-1f, Defective RFT1 causes CDG-1n, Defective DHDDS causes RP59, Defective DOLK causes DOLK-CDG, Defective SRD5A3 causes SRD5A3-CDG, KHRZ, Defective B4GALT1 causes CDG-2d, Defective MAN1B1 causes MRT15, Defective MGAT2 causes CDG-2a, Defective MOGS causes CDG-2b, and Defective ALG14 causes ALG14-CMS |
| _timestamp | 2026-03-23 12:43:21 |
| created | [InstanceEdit:548981] Jassal, B, 2010-03-15 |
| height | 1356 |
| modified | [InstanceEdit:1679954] Wu, G, 2011-10-20 [InstanceEdit:1922881] Rothfels, K, 2011-11-02 [InstanceEdit:3558427] Jassal, B, 2013-05-21 [InstanceEdit:4420216] Jassal, B, 2013-08-30 [InstanceEdit:4551778] Jassal, B, 2013-09-16 [InstanceEdit:4570574] Jassal, B, 2013-09-23 [InstanceEdit:4582403] Jassal, B, 2013-09-23 [InstanceEdit:4595723] Jassal, B, 2013-09-23 [InstanceEdit:4616036] Jassal, B, 2013-09-27 [InstanceEdit:4628430] Jassal, B, 2013-09-27 [InstanceEdit:4687781] Jassal, B, 2013-10-17 [InstanceEdit:4700232] Jassal, B, 2013-10-17 [InstanceEdit:4703354] Jassal, B, 2013-10-17 [InstanceEdit:4724336] Jassal, B, 2013-10-23 [InstanceEdit:4755549] Jassal, B, 2013-10-25 [InstanceEdit:4793951] Jassal, B, 2013-10-29 [InstanceEdit:4836510] Jassal, B, 2013-10-30 [InstanceEdit:4839807] Jassal, B, 2013-11-04 [InstanceEdit:4960937] Jassal, B, 2013-11-04 [InstanceEdit:5083143] Jassal, B, 2013-11-05 [InstanceEdit:5602078] Matthews, Lisa, 2014-06-18 [InstanceEdit:5633250] Jassal, Bijay, 2014-10-31 [InstanceEdit:5674151] Jassal, Bijay, 2015-02-11 [InstanceEdit:5674152] Jassal, Bijay, 2015-02-11 [InstanceEdit:6781879] Jassal, Bijay, 2015-06-03 [InstanceEdit:6782704] Jassal, Bijay, 2015-06-08 [InstanceEdit:6782714] Jassal, Bijay, 2015-06-08 [InstanceEdit:6784252] Jassal, Bijay, 2015-06-19 [InstanceEdit:6784254] Jassal, Bijay, 2015-06-19 [InstanceEdit:6787667] Jassal, Bijay, 2015-07-15 [InstanceEdit:6787668] Jassal, Bijay, 2015-07-15 [InstanceEdit:6787687] Jassal, Bijay, 2015-07-15 [InstanceEdit:6789878] Jassal, Bijay, 2015-08-05 [InstanceEdit:6789891] Jassal, Bijay, 2015-08-05 [InstanceEdit:6792855] Jassal, Bijay, 2015-08-28 [InstanceEdit:6793936] Jassal, Bijay, 2015-09-04 [InstanceEdit:6793938] Jassal, Bijay, 2015-09-04 [InstanceEdit:6814308] Jassal, Bijay, 2015-11-26 [InstanceEdit:8847597] Jassal, Bijay, 2015-12-01 [InstanceEdit:8847951] Jassal, Bijay, 2015-12-03 [InstanceEdit:8853373] Jassal, Bijay, 2016-01-22 [InstanceEdit:8853387] Jassal, Bijay, 2016-01-22 [InstanceEdit:8853700] Jassal, Bijay, 2016-01-25 [InstanceEdit:8862019] Jassal, Bijay, 2016-02-24 [InstanceEdit:8864056] Jassal, Bijay, 2016-03-11 [InstanceEdit:8864057] Jassal, Bijay, 2016-03-11 [InstanceEdit:8864062] Jassal, Bijay, 2016-03-11 [InstanceEdit:8866782] Jassal, Bijay, 2016-04-04 [InstanceEdit:8866901] Rothfels, Karen, 2016-04-04 [InstanceEdit:8867292] Jassal, Bijay, 2016-04-06 [InstanceEdit:8940090] Jupe, Steve, 2016-09-23 [InstanceEdit:8949379] D'Eustachio, Peter, 2016-11-22 [InstanceEdit:8949380] D'Eustachio, Peter, 2016-11-22 [InstanceEdit:9632497] Jassal, Bijay, 2018-12-19 [InstanceEdit:9645116] Wu, G, 2019-05-03 [InstanceEdit:9645351] Jassal, Bijay, 2019-05-09 [InstanceEdit:9645352] Jassal, Bijay, 2019-05-09 [InstanceEdit:9689736] Jassal, Bijay, 2020-05-21 [InstanceEdit:9689801] Matthews, Lisa, 2020-05-21 [InstanceEdit:9697722] Jassal, Bijay, 2020-08-20 [InstanceEdit:9736293] Jassal, Bijay, 2021-07-06 [InstanceEdit:9753833] Jassal, Bijay, 2021-09-15 [InstanceEdit:9753835] Jassal, Bijay, 2021-09-15 [InstanceEdit:9909163] D'Eustachio, Peter, 2024-04-29 [InstanceEdit:9909224] D'Eustachio, Peter, 2024-04-30 [InstanceEdit:9909237] D'Eustachio, Peter, 2024-04-30 [InstanceEdit:9909253] D'Eustachio, Peter, 2024-05-01 [InstanceEdit:9909279] D'Eustachio, Peter, 2024-05-02 [InstanceEdit:9909282] D'Eustachio, Peter, 2024-05-02 [InstanceEdit:9909284] D'Eustachio, Peter, 2024-05-02 [InstanceEdit:9909291] D'Eustachio, Peter, 2024-05-03 [InstanceEdit:9910547] D'Eustachio, Peter, 2024-05-14 [InstanceEdit:9910565] D'Eustachio, Peter, 2024-05-15 [InstanceEdit:9910568] D'Eustachio, Peter, 2024-05-15 [InstanceEdit:9937296] D'Eustachio, Peter, 2025-01-30 [InstanceEdit:9937336] D'Eustachio, Peter, 2025-01-30 [InstanceEdit:9937353] D'Eustachio, Peter, 2025-01-30 [InstanceEdit:9937354] D'Eustachio, Peter, 2025-01-30 [InstanceEdit:9970535] D'Eustachio, Peter, 2025-10-30 [InstanceEdit:9971186] D'Eustachio, Peter, 2025-11-04 [InstanceEdit:9974412] D'Eustachio, Peter, 2025-11-21 [InstanceEdit:9985645] D'Eustachio, Peter, 2026-03-23 |
| representedPathway | [Pathway:446203] Asparagine N-linked glycosylation [Homo sapiens] [Pathway:4549380] Defective ALG1 causes CDG-1k [Homo sapiens] [Pathway:4551295] Defective ALG11 causes CDG-1p [Homo sapiens] [Pathway:4549349] Defective ALG2 causes CDG-1i [Homo sapiens] [Pathway:4549356] Defective DPAGT1 causes CDG-1j, CMSTA2 [Homo sapiens] [Pathway:4085023] Defective GFPT1 causes CMSTA1 [Homo sapiens] [Pathway:4043916] Defective MPI causes MPI-CDG [Homo sapiens] [Pathway:4043911] Defective PMM2 causes PMM2-CDG [Homo sapiens] [Pathway:4720489] Defective ALG12 causes CDG-1g [Homo sapiens] [Pathway:4720475] Defective ALG3 causes CDG-1d [Homo sapiens] [Pathway:4724289] Defective ALG6 causes CDG-1c [Homo sapiens] [Pathway:4724325] Defective ALG8 causes CDG-1h [Homo sapiens] [Pathway:4720454] Defective ALG9 causes CDG-1l [Homo sapiens] [Pathway:4717374] Defective DPM1 causes DPM1-CDG [Homo sapiens] [Pathway:4719377] Defective DPM2 causes DPM2-CDG [Homo sapiens] [Pathway:4719360] Defective DPM3 causes DPM3-CDG [Homo sapiens] [Pathway:4687000] Defective MPDU1 causes CDG-1f [Homo sapiens] [Pathway:4570571] Defective RFT1 causes CDG-1n [Homo sapiens] [Pathway:4755609] Defective DHDDS causes RP59 [Homo sapiens] [Pathway:4755583] Defective DOLK causes DOLK-CDG [Homo sapiens] [Pathway:4755579] Defective SRD5A3 causes SRD5A3-CDG, KHRZ [Homo sapiens] [Pathway:4793953] Defective B4GALT1 causes CDG-2d [Homo sapiens] [Pathway:4793950] Defective MAN1B1 causes MRT15 [Homo sapiens] [Pathway:4793952] Defective MGAT2 causes CDG-2a [Homo sapiens] [Pathway:4793954] Defective MOGS causes CDG-2b [Homo sapiens] [Pathway:5633231] Defective ALG14 causes ALG14-CMS [Homo sapiens] |
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textPosition="831 1115"> <Properties> <displayName>DbGP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="78" reactomeId="532542" position="1036 1126" bounds="1011 1111 50 30" textPosition="1015 1115" /> <org.gk.render.RenderableChemical id="79" reactomeId="29410" position="651 1180" bounds="612 1157 79 47" textPosition="623 1169"> <Properties> <displayName>UDP-Glc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="80" reactomeId="29420" position="2408 592" bounds="2387 577 42 30" textPosition="2391 581" /> <org.gk.render.RenderableChemical id="81" reactomeId="29420" position="2674 575" bounds="2653 560 42 30" textPosition="2657 564"> <Properties> <displayName>GDP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="82" reactomeId="29420" position="2196 583" bounds="2175 568 42 30" textPosition="2179 572" /> 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textPosition="2032 289" /> <org.gk.render.RenderableEntitySet id="1015" reactomeId="964764" position="2097 469" bounds="2045 458 104 22" textPosition="2045 458"> <Properties> <displayName>MAN1A1/A2/C1</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="1021" reactomeId="964831" position="1698 426" bounds="1637 404 122 44" textPosition="1641 408"> <Properties> <displayName>(GlcNAc)2 (Man)8 glycans</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="1023" reactomeId="964828" position="1554 371" bounds="1488 356 132 30" textPosition="1492 360"> <Properties> <displayName>(GlcNAc)2 (Man)7bc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1029" reactomeId="914003" position="1582 287" bounds="1538 272 89 30" textPosition="1542 276" /> <org.gk.render.RenderableChemical id="1030" reactomeId="964837" position="1317 378" bounds="1256 356 122 44" textPosition="1260 360"> <Properties> <displayName>(GlcNAc)3 (Man)5 (Asn)1</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1031" reactomeId="205687" position="1419 312" bounds="1399 297 41 30" textPosition="1403 301" /> <org.gk.render.RenderableProtein id="1032" reactomeId="964750" position="1462 467" bounds="1436 456 52 22" textPosition="1436 456"> <Properties> <displayName>MGAT1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1038" reactomeId="975910" position="3502 373" bounds="3481 358 42 30" textPosition="3485 362" /> <org.gk.render.RenderableEntity id="1039" reactomeId="981613" position="3706 420" bounds="3640 395 133 50" textPosition="3640 395"> <Properties> <displayName>Glycoprotein with bifurcating GlcNAc in position 3</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableProtein id="1040" reactomeId="975897" position="3598 467" bounds="3572 456 52 22" textPosition="3572 456"> <Properties> <displayName>MGAT3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1046" reactomeId="975819" position="1580 190" bounds="1519 168 122 44" textPosition="1523 172"> <Properties> <displayName>(GlcNAc)3 (Man)3 (Asn)1</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="1047" reactomeId="975821" position="1220 313" bounds="1180 302 80 22" textPosition="1180 302"> <Properties> <displayName>MAN2:Zn2+</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="1049" reactomeId="914003" position="3488 423" bounds="3444 408 89 30" textPosition="3448 412" /> <org.gk.render.RenderableChemical id="1059" reactomeId="975822" position="1298 171" bounds="1237 149 122 44" textPosition="1241 153"> <Properties> <displayName>(GlcNAc)4 (Man)3 (Asn)1</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="1060" reactomeId="975830" position="1209 256" bounds="1183 245 52 22" textPosition="1183 245"> <Properties> <displayName>MGAT2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1062" reactomeId="205683" position="3386 402" bounds="3352 387 68 30" textPosition="3356 391" /> <org.gk.render.RenderableChemical id="1063" reactomeId="205689" position="3160 295" bounds="3139 280 42 30" textPosition="3143 284" /> <org.gk.render.RenderableEntity id="1064" reactomeId="1028779" position="3177 374" bounds="3118 349 118 50" textPosition="3124 363"> <Properties> <displayName>NGP:1,6-GlcNAc</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableProtein id="1065" reactomeId="1028782" position="3329 459" bounds="3310 448 39 22" textPosition="3310 448"> <Properties> <displayName>FUT8</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntity id="1071" reactomeId="981616" position="3930 385" bounds="3868 367 125 36" textPosition="3868 367"> <Properties> <displayName>Glycoprotein with GlcNAc in position 4</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableEntitySet id="1072" reactomeId="975913" position="3838 470" bounds="3809 459 58 22" textPosition="3809 459"> <Properties> <displayName>MGAT4s</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="1074" reactomeId="914003" position="3584 301" bounds="3540 286 89 30" textPosition="3544 290"> <Properties> <displayName>UDP-GlcNAc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntity id="1088" reactomeId="981617" position="4118 319" bounds="4056 301 125 36" textPosition="4056 301"> <Properties> <displayName>Glycoprotein with GlcNAc in position 5</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableProtein id="1089" reactomeId="975896" position="4007 469" bounds="3981 458 52 22" textPosition="3981 458"> <Properties> <displayName>MGAT5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1091" reactomeId="735682" position="4062 242" bounds="4029 227 67 30" textPosition="4033 231"> <Properties> <displayName>UDP-Gal</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntity id="1092" reactomeId="981618" position="4370 300" bounds="4314 282 112 36" textPosition="4314 282"> <Properties> <displayName>Glycoprotein with galactose</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableEntitySet id="1093" reactomeId="975898" position="4271 469" bounds="4230 451 82 36" textPosition="4230 451"> <Properties> <displayName>B4GALT1-6 homodimers</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="1123" reactomeId="975925" position="3161 186" bounds="3132 171 58 30" textPosition="3134 175"> <Properties> <displayName>Neu5Ac</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntity id="1124" reactomeId="981615" position="3378 187" bounds="3322 169 112 36" textPosition="3334 169"> <Properties> <displayName>Glycoprotein-Neu5Ac</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableProtein id="1125" reactomeId="975899" position="3270 126" bounds="3239 115 62 22" textPosition="3239 115"> <Properties> <displayName>ST6GAL1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="1131" reactomeId="1022134" position="3497 127" bounds="3457 116 80 22" textPosition="3457 116"> <Properties> <displayName>ST8SIA2,3,6</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="1133" reactomeId="981490" position="3004 130" bounds="2973 119 62 22" textPosition="2973 119"> <Properties> <displayName>ST3GAL4</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1246" reactomeId="113592" position="246 963" bounds="226 948 40 30" textPosition="230 952" /> <org.gk.render.RenderableChemical id="1247" reactomeId="191403" position="246 909" bounds="214 894 65 30" textPosition="218 898"> <Properties> <displayName>MVA5PP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1250" reactomeId="191362" position="413 933" bounds="393 918 41 30" textPosition="397 922"> <Properties> <displayName>IPPP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="1251" reactomeId="191341" position="331 886" bounds="294 875 74 22" textPosition="294 875" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MVD dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="1312" reactomeId="29372" position="349 976" bounds="336 961 27 30" textPosition="340 965" /> <org.gk.render.ProcessNode id="1322" reactomeId="199977" position="2804 550" bounds="2744 517 121 67" textPosition="2758 521"> <Properties> <displayName>ER to Golgi Anterograde Transport</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableChemical id="1324" reactomeId="4419987" position="346 846" bounds="315 831 62 30" textPosition="319 835"> <Properties> <displayName>E,E-FPP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1325" reactomeId="4419982" position="471 804" bounds="448 789 46 30" textPosition="452 793"> <Properties> <displayName>pPPP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1357" reactomeId="29356" position="350 749" bounds="329 734 43 30" textPosition="333 738" /> <org.gk.render.RenderableChemical id="1358" reactomeId="4419981" position="500 667" bounds="472 652 56 30" textPosition="476 656"> <Properties> <displayName>pPNOL</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntity id="1359" reactomeId="4420020" position="482 730" bounds="440 713 84 35" textPosition="441 713"> <Properties> <displayName>pPPP phosphatase</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableChemical id="1361" reactomeId="111294" position="374 657" bounds="357 642 34 30" textPosition="361 646" /> <org.gk.render.RenderableChemical id="1392" reactomeId="29364" position="786 572" bounds="757 557 59 30" textPosition="761 561"> <Properties> <displayName>NADPH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1393" reactomeId="29366" position="883 572" bounds="853 557 60 30" textPosition="857 561" /> <org.gk.render.RenderableProtein id="1394" reactomeId="469663" position="719 686" bounds="691 675 56 22" textPosition="691 675"> <Properties> <displayName>SRD5A3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.ProcessNode id="1395" reactomeId="4085001" position="609 460" bounds="523 418 172 84" textPosition="537 445"> <Properties> <displayName>Sialic acid metabolism</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableProtein id="1396" reactomeId="4628428" position="4037 856" bounds="4010 845 54 23" textPosition="4012 845"> <Properties> <displayName>MPDU1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.ProcessNode id="1397" reactomeId="1630316" position="4466 416" bounds="4388 386 157 61" textPosition="4402 394"> <Properties> <displayName>Glycosaminoglycan metabolism</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableChemical id="1399" reactomeId="162681" position="453 1023" bounds="402 1013 102 21" textPosition="418 1013"> <Properties> <displayName>DOLP-Man</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="1404" reactomeId="6781883" position="3118 861" bounds="3059 836 119 50" textPosition="3064 836" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>unfolded protein:(Glc)1 (GlcNAc)2 (Man)8b</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="1407" reactomeId="6781870" position="3341 954" bounds="3320 939 43 30" textPosition="3324 943" /> <org.gk.render.RenderableChemical id="1408" reactomeId="6781870" position="3150 952" bounds="3129 937 43 30" textPosition="3133 941" /> <org.gk.render.RenderableComplex id="1414" reactomeId="912284" position="2763 881" bounds="2704 863 118 36" textPosition="2704 863" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>unfolded protein:(GlcNAc)2 (Man)8b</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="1432" reactomeId="6782581" position="3248 959" bounds="3196 948 104 22" textPosition="3196 948"> <Properties> <displayName>MAN1B1,EDEM2</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="1434" reactomeId="6782692" position="2707 984" bounds="2652 966 110 36" textPosition="2652 966" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>unfolded protein:(GlcNAc)2 (Man)5</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="1441" reactomeId="6781870" position="2813 920" bounds="2796 905 35 30" textPosition="2796 909" /> <org.gk.render.RenderableEntitySet id="1442" reactomeId="6782691" position="2680 932" bounds="2648 921 64 23" textPosition="2649 921"> <Properties> <displayName>EDEM1,3</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="1556" reactomeId="29356" position="5271 232" bounds="5254 218 34 29" textPosition="5254 221" /> <org.gk.render.RenderableChemical id="1557" reactomeId="6787618" position="5212 191" bounds="5183 170 59 42" textPosition="5183 173"> <Properties> <displayName>GDP-DHDMan</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="1558" reactomeId="6787620" position="5335 146" bounds="5314 134 43 24" textPosition="5314 135"> <Properties> <displayName>GMDS</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1560" reactomeId="162860" position="5414 191" bounds="5382 176 64 30" textPosition="5382 180" /> <org.gk.render.RenderableChemical id="1562" reactomeId="6787646" position="5027 191" bounds="4989 174 77 34" textPosition="4989 180"> <Properties> <displayName>GDP-KDGal</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="1563" reactomeId="6787635" position="5017 129" bounds="4971 118 92 22" textPosition="4979 118" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GFUS dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="1565" reactomeId="70106" position="4973 265" bounds="4957 250 32 30" textPosition="4959 254" /> <org.gk.render.RenderableChemical id="1566" reactomeId="742368" position="4729 261" bounds="4697 244 64 35" textPosition="4699 250"> <Properties> <displayName>GDP-Fuc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1568" reactomeId="29364" position="5011 234" bounds="4982 219 59 30" textPosition="4986 223" /> <org.gk.render.RenderableChemical id="1570" reactomeId="29366" position="4782 163" bounds="4752 148 60 30" textPosition="4756 152"> <Properties> <displayName>NADP+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1574" reactomeId="6787542" position="4962 386" bounds="4937 371 51 30" textPosition="4941 375"> <Properties> <displayName>Fuc1P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="1576" reactomeId="6787531" position="5084 340" bounds="5062 329 44 22" textPosition="5066 329"> <Properties> <displayName>FCSK</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="1578" reactomeId="6787538" position="4850 328" bounds="4825 317 51 22" textPosition="4831 317"> <Properties> <displayName>FPGT</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1580" reactomeId="111294" position="4774 424" bounds="4757 409 34 30" textPosition="4761 413" /> <org.gk.render.RenderableChemical id="1582" reactomeId="29438" position="4926 424" bounds="4906 409 41 30" textPosition="4910 413"> <Properties> <displayName>GTP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="1588" reactomeId="742352" position="3511 470" bounds="3479 457 64 26" textPosition="3481 459"> <Properties> <displayName>SLC35C1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1589" reactomeId="6787678" position="5212 386" bounds="5178 371 69 30" textPosition="5182 375"> <Properties> <displayName>beta-Fuc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1590" reactomeId="113592" position="5174 424" bounds="5154 409 40 30" textPosition="5158 413" /> <org.gk.render.RenderableChemical id="1592" reactomeId="6787679" position="5395 385" bounds="5360 370 71 31" textPosition="5362 374"> <Properties> <displayName>alpha-Fuc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="1593" reactomeId="6787682" position="5305 330" bounds="5263 319 85 23" textPosition="5266 320" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>FUOM dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="1599" reactomeId="5693930" position="2896 378" bounds="2826 363 141 30" textPosition="2833 367"> <Properties> <displayName>Gal1,3GlcNAc group</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1600" reactomeId="5693933" position="3126 429" bounds="3067 407 118 44" textPosition="3078 411"> <Properties> <displayName>Gal1,3Fuc1,4GlcNAc group</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="1601" reactomeId="5693934" position="2994 466" bounds="2970 455 48 22" textPosition="2975 455"> <Properties> <displayName>FUT3</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="1603" reactomeId="205683" position="2904 431" bounds="2870 416 68 30" textPosition="2874 420" /> <org.gk.render.RenderableCompartment id="1604" reactomeId="161320" position="835 200" bounds="520 112 631 177" textPosition="690 199" bgColor="250 240 240" lineColor="255 153 102" insets="527 122 617 159"> <Properties> <displayName>lysosomal lumen</displayName> </Properties> <Components> <Component id="1605" /> <Component id="1606" /> <Component id="1607" /> <Component id="1608" /> <Component id="1609" /> <Component id="1610" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="1606" reactomeId="1605715" position="899 171" bounds="877 156 44 30" textPosition="882 160" /> <org.gk.render.RenderableEntity id="1607" reactomeId="6784247" position="920 244" bounds="863 233 114 22" textPosition="867 233" /> <org.gk.render.RenderableChemical id="1608" reactomeId="6784248" position="1109 224" bounds="1087 209 44 31" textPosition="1092 213"> <Properties> <displayName>NGP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="1609" reactomeId="6784249" position="1100 162" bounds="1071 143 58 39" textPosition="1071 151"> <Properties> <displayName>L-fucose</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="1610" reactomeId="5693805" position="982 146" bounds="950 127 64 38" textPosition="953 129" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>FUCA1 tetramer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="2179" reactomeId="741440" position="2628 219" bounds="2606 204 45 30" textPosition="2610 208" /> <org.gk.render.RenderableComplex id="2180" reactomeId="6793934" position="2604 173" bounds="2557 155 94 36" textPosition="2558 169" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>glyco-Lutropin</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="2181" reactomeId="742343" position="2823 217" bounds="2804 202 39 30" textPosition="2808 206"> <Properties> 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<displayName>S-HNK1 carbohydrate</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="2558" reactomeId="6786025" position="2282 129" bounds="2254 118 56 22" textPosition="2254 118"> <Properties> <displayName>CHST10</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2559" reactomeId="741440" position="2200 216" bounds="2178 201 45 30" textPosition="2182 205"> <Properties> <displayName>PAPS</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2560" reactomeId="742343" position="2407 217" bounds="2388 202 39 30" textPosition="2392 206" /> <org.gk.render.RenderableComplex id="2561" reactomeId="6806947" position="492 844" bounds="449 833 86 22" textPosition="449 833" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>DHDDS:NUS1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="2630" reactomeId="6803769" position="183 134" bounds="127 123 112 22" textPosition="127 123"> <Properties> <displayName>ManNAc, ManNGc</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="2631" reactomeId="6803785" position="183 223" bounds="133 212 100 22" textPosition="133 212"> <Properties> <displayName>GlcNAc, GlcNGc</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="2632" reactomeId="6803782" position="108 173" bounds="66 162 85 22" textPosition="66 162" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>RENBP dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="2634" reactomeId="113592" position="138 258" bounds="118 243 40 30" textPosition="122 247"> <Properties> <displayName>ATP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2635" reactomeId="29370" position="225 348" bounds="205 333 41 30" textPosition="209 337" /> <org.gk.render.RenderableEntitySet id="2636" reactomeId="6803738" position="294 312" bounds="251 294 87 36" textPosition="251 294"> <Properties> <displayName>GlcNAc-6-P, GlcNGc-6-P</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="2637" reactomeId="6803750" position="107 313" bounds="67 302 81 22" textPosition="67 302" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>NAGK dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="2639" reactomeId="70106" position="243 266" bounds="227 251 32 30" textPosition="229 255" /> <org.gk.render.RenderableChemical id="2641" reactomeId="29356" position="373 282" bounds="352 267 43 30" textPosition="356 271" /> <org.gk.render.RenderableChemical id="2642" reactomeId="6803743" position="372 353" bounds="328 338 88 30" textPosition="332 342"> <Properties> <displayName>GlcNGc-6-P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2643" reactomeId="193473" position="485 272" bounds="465 257 41 30" textPosition="469 261"> <Properties> <displayName>CCA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="2644" reactomeId="6803808" position="428 262" bounds="397 251 62 22" textPosition="397 251"> <Properties> <displayName>AMDHD2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2663" reactomeId="29356" position="635 1266" bounds="610 1251 51 31" textPosition="618 1255"> <Properties> <displayName>H2O</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="2664" reactomeId="29548" position="413 1195" bounds="392 1181 42 29" textPosition="397 1184"> <Properties> <displayName>G1P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="2665" reactomeId="6809220" position="533 1185" bounds="501 1173 64 24" textPosition="504 1174"> <Properties> <displayName>NUDT14</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="2667" reactomeId="109402" position="413 1234" bounds="392 1219 43 31" textPosition="397 1223" /> <org.gk.render.RenderableEntitySet id="2668" reactomeId="8852845" position="2852 1061" bounds="2790 1043 125 36" textPosition="2790 1043"> <Properties> <displayName>unfolded protein:(GlcNAc)2 (Man)9-5</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntity id="2987" reactomeId="1022114" position="3016 1262" bounds="2961 1248 111 28" textPosition="2964 1251" /> <org.gk.render.RenderableEntitySet id="2988" reactomeId="8852852" position="3093 1209" bounds="3031 1198 125 22" textPosition="3031 1198"> <Properties> <displayName>(GlcNAc)2 (Man)9-5</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="2990" reactomeId="8850590" position="2909 1135" bounds="2859 1117 101 36" textPosition="2859 1117" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Deglycosylation complex</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntity id="2993" reactomeId="8853371" position="2311 1266" bounds="2257 1248 109 36" textPosition="2257 1248"> <Properties> <displayName>unfolded protein:GlcNAc</displayName> </Properties> </org.gk.render.RenderableEntity> <org.gk.render.RenderableEntitySet id="2994" reactomeId="8853381" position="2249 1209" bounds="2195 1198 109 22" textPosition="2195 1198"> <Properties> <displayName>GlcNAc (Man)9-5</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="2999" reactomeId="8853386" position="2420 1165" bounds="2393 1154 55 22" textPosition="2393 1154"> <Properties> <displayName>ENGASE</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.ProcessNode id="3335" reactomeId="8853383" position="2018 1208" bounds="1947 1175 142 66" textPosition="1963 1179"> <Properties> <displayName>Lysosomal oligosaccharide catabolism</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableChemical id="3355" reactomeId="8855720" position="5485 19" bounds="5440 4 91 30" textPosition="5444 8"> <Properties> <displayName>proteoglycan</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="3356" reactomeId="8855701" position="5460 98" bounds="5407 75 106 47" textPosition="5411 72" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PALM-C36-ASGR1:PALM-C54,58-ASGR2</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="3357" reactomeId="8855703" position="5657 96" bounds="5594 71 126 50" textPosition="5594 71" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PALM-C36-ASGR1:PALM-C54,58-ASGR2:proteoglycan</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="3390" reactomeId="8855962" position="4490 159" bounds="4464 148 53 22" textPosition="4468 148"> <Properties> <displayName>UMOD</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.35555555555555557" relativeY="0.0" label="G" trackId="0" reactomeId="8856003" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3392" reactomeId="8855988" position="4486 310" bounds="4450 299 73 22" textPosition="4450 299"> <Properties> <displayName>Sda-UMOD</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.2191780821917808" relativeY="0.0" label="G" trackId="0" reactomeId="8855987" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="3393" reactomeId="8855939" position="4562 230" bounds="4526 219 72 22" textPosition="4526 219"> <Properties> <displayName>B4GALNT2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3397" reactomeId="735682" position="4432 194" bounds="4399 179 67 30" textPosition="4403 183" /> <org.gk.render.RenderableChemical id="3399" reactomeId="205687" position="4532 276" bounds="4512 261 41 30" textPosition="4516 265"> <Properties> <displayName>UDP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="3400" reactomeId="3558426" position="1031 323" bounds="1004 312 55 22" textPosition="1004 312" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>2xUAP1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="3402" reactomeId="8866894" position="2590 1209" bounds="2533 1184 115 50" textPosition="2533 1184" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Ub-unfolded protein:(GlcNAc)2 (Man)9-5</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="3403" reactomeId="8866892" position="2709 1106" bounds="2648 1088 122 36" textPosition="2648 1088" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>OS9:SEL1:ERAD E3 ligases:DERL2</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3404" reactomeId="29356" position="2832 1244" bounds="2811 1229 43 30" textPosition="2815 1233" /> <org.gk.render.RenderableChemical id="3405" reactomeId="29356" position="2467 1238" bounds="2446 1223 43 30" textPosition="2450 1227" /> <org.gk.render.RenderableComplex id="3406" reactomeId="8867287" position="2592 1059" bounds="2535 1034 115 50" textPosition="2535 1034" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableEntitySet id="3408" reactomeId="113595" position="2834 1149" bounds="2822 1138 24 22" textPosition="2822 1138"> <Properties> <displayName>Ub</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="3410" reactomeId="110096" position="801 1180" bounds="781 1165 41 30" textPosition="785 1169" /> <org.gk.render.RenderableChemical id="3412" reactomeId="29420" position="358 1040" bounds="337 1025 42 30" textPosition="341 1029" /> <org.gk.render.RenderableComplex id="3414" reactomeId="449326" position="1671 679" bounds="1644 661 54 36" textPosition="1645 661" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ALG13:ALG14</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3416" reactomeId="110096" position="1758 537" bounds="1738 522 41 30" textPosition="1742 526" /> <org.gk.render.RenderableChemical id="3660" reactomeId="113592" position="90 484" bounds="70 469 40 31" textPosition="74 473" /> <org.gk.render.RenderableChemical id="3661" reactomeId="429579" position="142 444" bounds="122 429 41 31" textPosition="126 433" /> <org.gk.render.RenderableChemical id="3662" reactomeId="29370" position="103 624" bounds="83 609 41 31" textPosition="87 613"> <Properties> <displayName>ADP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="3663" reactomeId="70395" position="204 539" bounds="187 528 34 23" textPosition="187 528"> <Properties> <displayName>HK1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3665" reactomeId="70106" position="86 584" bounds="70 569 32 30" textPosition="72 573"> <Properties> <displayName>H+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3709" reactomeId="70106" position="216 753" bounds="200 738 32 30" textPosition="202 742" /> <org.gk.render.RenderableComplex id="3718" reactomeId="9909250" position="226 812" bounds="205 801 42 23" textPosition="205 802" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>GMPP</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3884" reactomeId="111294" position="350 795" bounds="333 780 34 30" textPosition="337 784"> <Properties> <displayName>PPi</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4015" reactomeId="29360" position="493 572" bounds="467 557 53 31" textPosition="471 561"> <Properties> <displayName>NAD+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4016" reactomeId="73473" position="622 572" bounds="596 557 52 31" textPosition="600 561"> <Properties> <displayName>NADH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4017" reactomeId="9937308" position="639 671" bounds="615 656 48 31" textPosition="619 660"> <Properties> <displayName>pNAL</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="4018" reactomeId="9937274" position="566 686" bounds="542 675 49 23" textPosition="542 675"> <Properties> <displayName>DHRSX</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="4020" reactomeId="70106" position="558 572" bounds="542 557 32 30" textPosition="544 561" /> <org.gk.render.RenderableChemical id="4065" reactomeId="9937289" position="796 667" bounds="768 652 57 31" textPosition="772 656"> <Properties> <displayName>DCHAL</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4067" reactomeId="70106" position="690 572" bounds="674 557 32 30" textPosition="676 561" /> <org.gk.render.RenderableChemical id="4328" reactomeId="70106" position="1066 549" bounds="1050 534 32 30" textPosition="1052 538" /> <org.gk.render.RenderableChemical id="4502" reactomeId="70106" position="1159 554" bounds="1143 539 32 30" textPosition="1145 543" /> <org.gk.render.RenderableChemical id="4510" reactomeId="29370" position="5008 424" bounds="4988 409 41 31" textPosition="4992 413" /> <org.gk.render.RenderableChemical id="4512" reactomeId="70106" position="5051 444" bounds="5035 429 32 30" textPosition="5037 433" /> <org.gk.render.RenderableChemical id="4521" reactomeId="70106" position="4882 444" bounds="4866 429 32 30" textPosition="4868 433" /> <org.gk.render.RenderableChemical id="4529" reactomeId="744239" position="4523 350" bounds="4502 335 43 31" textPosition="4506 339"> <Properties> <displayName>GMP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4530" reactomeId="113578" position="3371 517" bounds="3350 502 43 31" textPosition="3354 506" /> <org.gk.render.RenderableChemical id="4531" reactomeId="29370" position="400 971" bounds="380 956 41 31" textPosition="384 960" /> 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</Outputs> <Catalysts> <Catalyst id="2" points="5478 700" /> </Catalysts> <Properties> <displayName>Transfer of N-glycan to the protein</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="84" reactomeId="446194" points="4963 591, 5116 591, 5179 750, 5207 750, 5236 750" position="5207 750" lineWidth="1.0"> <Inputs> <Input id="37" points="5046 658" /> <Input id="521" points="4538 666, 4549 591" /> </Inputs> <Outputs> <Output id="32" points="5309 708" /> <Output id="111" points="4699 704, 4742 821, 5120 822" /> </Outputs> <Catalysts> <Catalyst id="17" points="5208 708" /> </Catalysts> <Properties> <displayName>Addition of a third glucose to the N-glycan precursor by an ALG10 homologue</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="85" reactomeId="446191" points="1371 616, 1423 617, 1464 617" position="1423 617" lineWidth="1.0"> <Inputs> <Input id="42" points="1123 685, 1150 734, 1312 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658" position="2810 626" lineWidth="1.0"> <Inputs> <Input id="38" /> </Inputs> <Outputs> <Output id="9" /> </Outputs> <Catalysts> <Catalyst id="14" points="2810 669" /> </Catalysts> <Properties> <displayName>Flipping of the N-glycan precursor to inside the ER</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="88" reactomeId="446189" points="4842 620, 4860 620, 4935 759, 4975 760" position="4935 759" lineWidth="1.0"> <Inputs> <Input id="11" points="4812 659" /> <Input id="521" points="4541 666, 4556 620" /> </Inputs> <Outputs> <Output id="37" points="5045 708" /> <Output id="111" points="4699 704, 4733 796, 4975 796" /> </Outputs> <Catalysts> <Catalyst id="21" points="4943 700" /> </Catalysts> <Properties> <displayName>Addition of a second glucose to the N-glycan precursor by ALG8</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="89" reactomeId="446188" points="3180 751, 3242 751, 3275 752" position="3242 751" lineWidth="1.0"> <Inputs> <Input id="9" points="3029 700" /> <Input id="40" points="3165 718" /> </Inputs> <Outputs> <Output id="35" points="3415 704" /> <Output id="24" points="3335 702" /> </Outputs> <Catalysts> <Catalyst id="16" points="3242 696" /> </Catalysts> <Activators> <Activator id="1396" points="4007 851, 3590 776" /> </Activators> <Properties> <displayName>ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="90" reactomeId="449718" points="2289 632, 2332 632, 2375 632" position="2332 632" lineWidth="1.0"> <Inputs> <Input id="39" points="1881 551, 2223 551" /> <Input id="18" points="2271 651" /> </Inputs> <Outputs> <Output id="30" points="2407 649" /> <Output id="80" points="2395 610" /> </Outputs> <Catalysts> <Catalyst id="31" points="2116 696, 2132 718, 2332 718" /> </Catalysts> <Properties> <displayName>Addition of a third mannose to the N-glycan precursor by ALG2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="92" reactomeId="446208" points="2074 611, 2104 611, 2153 611" position="2104 611" lineWidth="1.0"> <Inputs> <Input id="22" points="2030 655" /> <Input id="39" points="1881 550, 2036 550" /> </Inputs> <Outputs> <Output id="18" points="2219 651" /> <Output id="82" points="2172 596" /> </Outputs> <Catalysts> <Catalyst id="31" points="2108 668" /> </Catalysts> <Properties> <displayName>Addition of a second mannose to the N-glycan precursor by ALG2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="93" reactomeId="446218" points="1876 612, 1920 612, 1972 612" position="1920 612" lineWidth="1.0"> <Inputs> <Input id="13" points="1842 657" /> <Input id="39" points="1849 569" /> </Inputs> <Outputs> <Output id="7" points="1990 594" /> <Output id="22" points="2005 655" /> </Outputs> <Catalysts> <Catalyst id="20" points="1918 675" /> </Catalysts> <Properties> <displayName>Addition of the first mannose to the N-glycan precursor by ALG1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="94" reactomeId="446187" points="2514 613, 2567 613, 2614 613" position="2567 613" lineWidth="1.0"> <Inputs> <Input id="30" points="2469 649" /> <Input id="39" stoichiometry="2" points="1881 550, 2468 550" /> </Inputs> <Outputs> <Output id="38" points="2670 658" /> <Output id="81" stoichiometry="2" points="2650 588" /> </Outputs> <Catalysts> <Catalyst id="28" points="2567 673" /> </Catalysts> <Properties> <displayName>ALG11 transfers the fourth and fifth Man to the N-glycan precursor</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="95" reactomeId="446198" points="3955 730, 4001 731, 4041 730" position="4001 731" lineWidth="1.0"> <Inputs> <Input id="29" points="3912 713" /> <Input id="40" points="3195 705, 3446 747, 3896 747" /> </Inputs> <Outputs> <Output id="33" points="4084 710" /> <Output id="113" points="3766 667, 3790 644, 4041 643" /> </Outputs> <Catalysts> <Catalyst id="36" points="4000 696" /> </Catalysts> <Activators> <Activator id="1396" points="4033 842" /> </Activators> <Properties> <displayName>ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="96" reactomeId="446216" points="4187 719, 4209 719, 4262 718" position="4209 719" lineWidth="1.0"> <Inputs> <Input id="33" points="4165 710" /> <Input id="40" points="3195 706, 3426 756, 4136 756" /> </Inputs> <Outputs> <Output id="26" points="4343 698" /> <Output id="114" points="4274 699" /> </Outputs> <Catalysts> <Catalyst id="27" points="3655 672, 3783 606, 4209 606" /> </Catalysts> <Activators> <Activator id="1396" points="4051 842" /> </Activators> <Properties> <displayName>ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="97" reactomeId="446215" points="3572 733, 3632 733, 3679 733" position="3632 733" lineWidth="1.0"> <Inputs> <Input id="35" points="3520 709" /> <Input id="40" points="3195 703, 3446 733" /> </Inputs> <Outputs> <Output id="29" points="3801 702" /> <Output id="113" points="3729 703" /> </Outputs> <Catalysts> <Catalyst id="27" points="3632 697" /> </Catalysts> <Activators> <Activator id="1396" points="4007 847" /> </Activators> <Properties> <displayName>ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="98" reactomeId="446195" points="989 630, 1021 629, 1053 629" position="1021 629" lineWidth="1.0"> <Inputs> <Input id="41" points="965 609" /> <Input id="44" points="962 649" /> </Inputs> <Outputs> <Output id="42" points="1089 652" /> <Output id="46" points="1075 610" /> <Output id="4328" points="1063 567" /> </Outputs> <Catalysts> <Catalyst id="45" points="1020 673" /> </Catalysts> <Properties> <displayName>DOLK phosphorylates DCHOL to DOLP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="99" reactomeId="446200" points="1230 634, 1205 633, 1175 632" position="1205 633" lineWidth="1.0"> <Inputs> <Input id="48" points="1250 618" /> <Input id="49" points="1257 653" /> </Inputs> <Outputs> <Output id="47" points="1157 609" /> <Output id="42" points="1143 652" /> <Output id="4502" points="1162 572" /> </Outputs> <Catalysts> <Catalyst id="43" points="1203 671" /> </Catalysts> <Properties> <displayName>DOLPP1 dephosphorylates DOLDP to DOLP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="100" reactomeId="446185" points="783 321, 831 321, 875 321" position="831 321" lineWidth="1.0"> <Inputs> <Input id="63" /> </Inputs> <Outputs> <Output id="56" /> </Outputs> <Catalysts> <Catalyst id="51" points="831 350" /> </Catalysts> <Properties> <displayName>Isomerization of GlcNAc6P to GlcNAc1P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="101" reactomeId="449715" points="281 450, 281 417, 381 417" position="281 417" lineWidth="1.0"> <Inputs> <Input id="62" points="248 466" /> <Input id="66" points="281 480" /> </Inputs> <Outputs> <Output id="61" points="495 341" /> <Output id="55" points="403 435" /> </Outputs> <Catalysts> <Catalyst id="58" points="238 405" /> </Catalysts> <Properties> <displayName>GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="102" reactomeId="446204" points="993 383, 1033 383, 1075 383" position="1033 383" lineWidth="1.0"> <Inputs> <Input id="59" points="957 395" /> <Input id="56" points="933 339" /> <Input id="4551" points="968 424" /> </Inputs> <Outputs> <Output id="54" points="1095 364" /> <Output id="23" points="1330 554" /> </Outputs> <Catalysts> <Catalyst id="3400" points="1031 337" /> </Catalysts> <Properties> <displayName>GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="103" reactomeId="449734" points="586 322, 623 322, 663 322" position="623 322" lineWidth="1.0"> <Inputs> <Input id="52" points="551 348" /> <Input id="61" points="550 322" /> </Inputs> <Outputs> <Output id="63" points="704 322" /> <Output id="50" points="691 367" /> <Output id="4547" points="737 356" /> </Outputs> <Catalysts> <Catalyst id="237" points="623 346" /> </Catalysts> <Properties> <displayName>Acetylation of glucosamine 6-phosphate to GlcNAc6P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="104" reactomeId="532549" points="281 516, 281 552, 281 586" position="281 552" lineWidth="1.0"> <Inputs> <Input id="66" /> </Inputs> <Outputs> <Output id="67" /> </Outputs> <Catalysts> <Catalyst id="64" points="327 552" /> </Catalysts> <Properties> <displayName>MPI isomerises Fru6P to Man6P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="105" reactomeId="446221" points="160 781, 160 812, 161 863" position="160 812" lineWidth="1.0"> <Inputs> <Input id="65" points="159 752" /> <Input id="68" points="126 766" /> <Input id="3709" points="197 761" /> </Inputs> <Outputs> <Output id="69" points="126 878" /> <Output id="73" points="159 917" /> </Outputs> <Catalysts> <Catalyst id="3718" points="202 812" /> </Catalysts> <Inhibitors> <Inhibitor id="73" points="120 935, 76 935, 76 868" /> </Inhibitors> <Activators> <Activator id="68" points="102 777, 102 796" /> </Activators> <Properties> <displayName>GMPPB converts Mannose-1-phosphate to GDP-Mannose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="106" reactomeId="446201" points="266 622, 219 670, 173 716" position="219 670" lineWidth="1.0"> <Inputs> <Input id="67" /> </Inputs> <Outputs> <Output id="65" /> </Outputs> <Catalysts> <Catalyst id="70" points="179 670" /> </Catalysts> <Properties> <displayName>PMM1,2 isomerise Man6P to Man1P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="107" reactomeId="162721" points="308 1124, 423 1079, 424 1051" position="423 1079" lineWidth="1.0"> <Inputs> <Input id="463" points="428 1124" /> <Input id="73" points="170 953" /> </Inputs> <Outputs> <Output id="1399" points="442 1037" /> <Output id="3412" points="382 1043" /> </Outputs> <Catalysts> <Catalyst id="72" points="449 1079" /> </Catalysts> <Properties> <displayName>dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="109" reactomeId="446214" points="685 1083, 728 1083, 787 1084" position="728 1083" lineWidth="1.0"> <Inputs> <Input id="79" points="659 1154" /> <Input id="463" points="482 1119" /> </Inputs> <Outputs> <Output id="77" points="828 1108" /> <Output id="3410" points="798 1162" /> </Outputs> <Catalysts> <Catalyst id="76" points="728 1111" /> </Catalysts> <Properties> <displayName>Synthesis of dolichyl-phosphate-glucose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="110" reactomeId="446211" points="880 1125, 940 1125, 1008 1125" position="940 1125" lineWidth="1.0"> <Inputs> <Input id="77" /> </Inputs> <Outputs> <Output id="78" /> </Outputs> <Properties> <displayName>Flipping of dolichyl-phosphate-glucose into the ER lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="139" reactomeId="532667" points="5448 1030, 5422 1002, 5330 1003" position="5422 1002" lineWidth="1.0"> <Inputs> <Input id="238" /> </Inputs> <Outputs> <Output id="126" points="5282 1022" /> <Output id="131" points="5411 916" /> <Output id="239" points="5620 1080, 5620 1151, 5331 1152" /> </Outputs> <Catalysts> <Catalyst id="117" points="5429 975" /> </Catalysts> <Properties> <displayName>Removal of the second glucose by glucosidase II</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="140" reactomeId="548890" points="4580 1046, 4523 1045, 4664 964, 4730 917" position="4523 1045" lineWidth="1.0"> <Inputs> <Input id="240" /> </Inputs> <Outputs> <Output id="242" points="4216 1025" /> <Output id="241" points="4946 948" /> <Output id="131" points="5405 898" /> <Output id="547" points="4630 896" /> </Outputs> <Catalysts> <Catalyst id="567" points="4512 1006" /> </Catalysts> <Properties> <displayName>Removal of the third glucose by glucosidase II and release from the chaperone</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="142" reactomeId="532678" points="5549 810, 5541 835, 5541 858, 5541 887" position="5541 858" lineWidth="1.0"> <Inputs> <Input id="1" /> </Inputs> <Outputs> <Output id="131" points="5446 896" /> <Output id="135" points="5543 918" /> </Outputs> <Catalysts> <Catalyst id="118" points="5599 858" /> </Catalysts> <Properties> <displayName>Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="144" reactomeId="535717" points="5121 1045, 5120 1046, 5075 1046" position="5120 1046" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="126" points="5171 1047" /> <Input id="243" points="5210 953" /> </Inputs> <Outputs> <Output id="244" /> </Outputs> <Properties> <displayName>Binding of calnexin/calreticulin to the unfolded protein</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="145" reactomeId="548884" points="2848 828, 2913 828, 2988 828" position="2913 828" lineWidth="1.0"> <Inputs> <Input id="246" points="2790 823" /> <Input id="1414" points="2791 860" /> </Inputs> <Outputs> <Output id="248" points="3084 815" /> <Output id="1404" points="3056 845" /> </Outputs> <Catalysts> <Catalyst id="127" points="2913 856" /> </Catalysts> <Properties> <displayName>UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="542" reactomeId="901047" points="4904 1047, 4905 1048, 4854 1048" position="4905 1048" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="241" points="4965 966" /> <Input id="244" points="4952 1047" /> </Inputs> <Outputs> <Output id="543" /> </Outputs> <Properties> <displayName>Binding of ERp57</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="564" reactomeId="901006" points="5540 996, 5540 999, 5506 1030" position="5540 999" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="239" points="5607 1052" /> <Input id="135" points="5543 974" /> </Inputs> <Outputs> <Output id="238" /> </Outputs> <Properties> <displayName>Binding of Malectin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="624" reactomeId="915148" points="3037 724, 3034 639, 2816 443" position="3034 639" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="549" /> </Inputs> <Outputs> <Output id="625" /> </Outputs> <Properties> <displayName>Correctly folded glycoproteins translocate to the Golgi</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="642" reactomeId="901074" points="3260 911, 3120 907, 2999 907" position="3120 907" lineWidth="1.0"> <Inputs> <Input id="245" points="3380 930" /> <Input id="1407" points="3317 942" /> </Inputs> <Outputs> <Output id="644" points="2935 914" /> <Output id="1414" points="2825 887" /> </Outputs> <Catalysts> <Catalyst id="1432" points="3220 942" /> </Catalysts> <Properties> <displayName>MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="646" reactomeId="901039" points="3295 1004, 3248 1004, 2824 1007" position="3248 1004" lineWidth="1.0"> <Inputs> <Input id="245" points="3402 961" /> <Input id="1407" points="3327 972" /> </Inputs> <Outputs> <Output id="647" points="2630 1007" /> <Output id="644" points="2896 935" /> </Outputs> <Catalysts> <Catalyst id="1432" points="3248 976" /> </Catalysts> <Properties> <displayName>MAN1B1 hydrolyses 1,2-linked mannose (c branch)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="648" reactomeId="901024" points="3260 922, 3121 922, 3057 922" position="3121 922" lineWidth="1.0"> <Inputs> <Input id="1407" points="3317 945" /> <Input id="245" points="3380 933" /> </Inputs> <Outputs> <Output id="649" points="3041 939" /> <Output id="644" points="2935 917" /> </Outputs> <Catalysts> <Catalyst id="1432" points="3210 942" /> </Catalysts> <Properties> <displayName>MAN1B1 hydrolyses 1,2-linked mannose (a branch)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="650" reactomeId="901036" points="3110 960, 3145 992, 3065 992" position="3145 992" lineWidth="1.0"> <Inputs> <Input id="1408" points="3126 956" /> <Input id="649" points="3089 960" /> </Inputs> <Outputs> <Output id="644" points="2914 935, 2930 992" /> <Output id="651" points="3048 1048" /> </Outputs> <Catalysts> <Catalyst id="1432" points="3213 976" /> </Catalysts> <Properties> <displayName>MAN1B1 hydrolyses a second 1,2-linked mannose (a branch)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="958" reactomeId="912291" points="3101 769, 3161 790, 3410 919" position="3161 790" lineWidth="1.0"> <Inputs> <Input id="549" /> </Inputs> <Outputs> <Output id="245" /> </Outputs> <Properties> <displayName>Incorrectly folded glycoproteins translocate to the ERQC</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="970" reactomeId="1017228" points="3570 887, 4064 1099, 5167 1100, 5197 1078" position="4064 1099" lineWidth="1.0"> <Inputs> <Input id="247" /> </Inputs> <Outputs> <Output id="126" /> </Outputs> <Properties> <displayName>Glycoproteins with lesser folding defects get transported back to the ER and the CNX/CRT complex</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="979" reactomeId="947991" points="2600 808, 2601 523, 2602 435" position="2601 523" lineWidth="1.0"> <Inputs> <Input id="980" /> </Inputs> <Outputs> <Output id="981" /> </Outputs> <Catalysts> <Catalyst id="982" points="2567 522" /> </Catalysts> <Properties> <displayName>Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1011" reactomeId="964737" points="2150 389, 2097 422, 2071 422" position="2097 422" lineWidth="1.0"> <Inputs> <Input id="1012" /> </Inputs> <Outputs> <Output id="1013" points="2043 423" /> <Output id="1014" stoichiometry="4" points="2050 318" /> </Outputs> <Catalysts> <Catalyst id="1015" points="2097 452" /> </Catalysts> <Properties> <displayName>Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1020" reactomeId="964825" points="1765 425, 1793 425, 1849 425" position="1793 425" lineWidth="1.0"> <Inputs> <Input id="1021" /> </Inputs> <Outputs> <Output id="1013" points="1915 425" /> <Output id="1014" stoichiometry="3" points="2025 312" /> </Outputs> <Catalysts> <Catalyst id="1015" points="2039 469, 1793 471" /> </Catalysts> <Properties> <displayName>Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1022" reactomeId="964830" points="1574 389, 1601 405, 1816 353" position="1601 405" lineWidth="1.0"> <Inputs> <Input id="1023" /> </Inputs> <Outputs> <Output id="1013" points="1929 401" /> <Output id="1014" stoichiometry="2" points="2025 304" /> </Outputs> <Catalysts> <Catalyst id="1015" points="2039 469, 1601 472" /> </Catalysts> <Properties> <displayName>Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1028" reactomeId="964768" points="1531 327, 1461 376, 1428 376" position="1461 376" lineWidth="1.0"> <Inputs> <Input id="1013" points="1915 412" /> <Input id="1029" points="1562 305" /> </Inputs> <Outputs> <Output id="1030" points="1381 376" /> <Output id="1031" points="1421 330" /> </Outputs> <Catalysts> <Catalyst id="1032" points="1461 453" /> </Catalysts> <Properties> <displayName>Addition of GlcNAc to the glycan on the A arm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1037" reactomeId="975926" points="3562 420, 3597 421, 3637 420" position="3597 421" lineWidth="1.0"> <Inputs> <Input id="1038" points="3521 391" /> <Input id="1049" points="3536 421" /> </Inputs> <Outputs> <Output id="1039" /> </Outputs> <Catalysts> <Catalyst id="1040" points="3597 453" /> </Catalysts> <Properties> <displayName>Addition of a bifurcating GlcNAc to the N-glycan by MGAT3</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1045" reactomeId="975814" points="1317 353, 1317 314, 1487 238" position="1317 314" lineWidth="1.0"> <Inputs> <Input id="1030" /> </Inputs> <Outputs> <Output id="1046" points="1537 215" /> <Output id="1014" stoichiometry="2" points="2025 297" /> </Outputs> <Catalysts> <Catalyst id="1047" points="1266 313" /> </Catalysts> <Properties> <displayName>Trimming of mannoses on the alpha1,6 arm by MAN2A1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1058" reactomeId="975829" points="1384 249, 1277 257, 1276 227" position="1277 257" lineWidth="1.0"> <Inputs> <Input id="1046" points="1516 208" /> <Input id="1029" points="1535 278" /> </Inputs> <Outputs> <Output id="1059" points="1289 196" /> <Output id="1031" points="1396 299" /> </Outputs> <Catalysts> <Catalyst id="1060" points="1238 256" /> </Catalysts> <Properties> <displayName>Addition of a GlcNAc on the alpha 1,4 branch by MGAT2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1061" reactomeId="1028788" points="3363 372, 3329 372, 3284 372" position="3329 372" lineWidth="1.0"> <Inputs> <Input id="1062" points="3374 384" /> <Input id="1038" points="3478 372" /> </Inputs> <Outputs> <Output id="1063" points="3184 308" /> <Output id="1064" points="3239 372" /> </Outputs> <Catalysts> <Catalyst id="1065" points="3329 445" /> </Catalysts> <Properties> <displayName>FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1070" reactomeId="975903" points="3778 384, 3837 384, 3865 384" position="3837 384" lineWidth="1.0"> <Inputs> <Input id="1038" points="3526 373" /> <Input id="1074" points="3619 319" /> </Inputs> <Outputs> <Output id="1071" /> </Outputs> <Catalysts> <Catalyst id="1072" points="3837 453" /> </Catalysts> <Properties> <displayName>Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1087" reactomeId="975916" points="3863 319, 4007 319, 4053 319" position="4007 319" lineWidth="1.0"> <Inputs> <Input id="1038" points="3526 369" /> <Input id="1074" points="3632 303" /> </Inputs> <Outputs> <Output id="1088" /> </Outputs> <Catalysts> <Catalyst id="1089" points="4007 455" /> </Catalysts> <Properties> <displayName>Addition of GlcNAc to position 5 by MGAT5</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1090" reactomeId="975919" points="4190 273, 4270 302, 4311 301" position="4270 302" lineWidth="1.0"> <Inputs> <Input id="1091" points="4099 250" /> <Input id="1038" points="3503 355, 3510 273" /> </Inputs> <Outputs> <Output id="1092" /> </Outputs> <Catalysts> <Catalyst id="1093" points="4270 445" /> </Catalysts> <Properties> <displayName>Addition of galactose by beta 4-galactosyltransferases</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1122" reactomeId="975902" points="3255 185, 3269 185, 3319 185" position="3269 185" lineWidth="1.0"> <Inputs> <Input id="1123" points="3193 185" /> <Input id="1038" points="3482 355" /> </Inputs> <Outputs> <Output id="1124" /> </Outputs> <Catalysts> <Catalyst id="1125" points="3269 140" /> </Catalysts> <Properties> <displayName>ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1130" reactomeId="1022133" points="3458 254, 3498 186, 3437 186" position="3498 186" lineWidth="1.0"> <Inputs> <Input id="1123" points="3193 192" /> <Input id="1038" points="3496 355" /> </Inputs> <Outputs> <Output id="1124" /> </Outputs> <Catalysts> <Catalyst id="1131" points="3497 144" /> </Catalysts> <Properties> <displayName>ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1132" reactomeId="1022129" points="3097 246, 3096 128, 3170 111, 3337 111, 3368 166" position="3096 128" lineWidth="1.0"> <Inputs> <Input id="1123" points="3145 204" /> <Input id="1038" points="3478 366" /> </Inputs> <Outputs> <Output id="1124" /> </Outputs> <Catalysts> <Catalyst id="1133" points="3038 129" /> </Catalysts> <Properties> <displayName>ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1245" reactomeId="191414" points="299 930, 331 930, 360 932" position="331 930" lineWidth="1.0"> <Inputs> <Input id="1246" points="269 950" /> <Input id="1247" points="282 921" /> </Inputs> <Outputs> <Output id="1250" points="390 932" /> <Output id="4531" points="384 953" /> <Output id="1312" points="352 958" /> </Outputs> <Catalysts> <Catalyst id="1251" points="331 900" /> </Catalysts> <Properties> <displayName>MVD decarboxylates MVA5PP to IPPP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1323" reactomeId="4419978" points="410 865, 410 842, 410 812" position="410 842" lineWidth="1.0"> <Inputs> <Input id="1324" points="380 855" /> <Input id="1250" stoichiometry="20" points="412 915" /> </Inputs> <Outputs> <Output id="1325" points="445 807" /> <Output id="3884" stoichiometry="20" points="370 799" /> </Outputs> <Catalysts> <Catalyst id="2561" points="446 842" /> </Catalysts> <Properties> <displayName>DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1356" reactomeId="4419986" points="401 746, 402 731, 401 687" position="402 731" lineWidth="1.0"> <Inputs> <Input id="1325" points="452 786" /> <Input id="1357" points="375 747" /> </Inputs> <Outputs> <Output id="1358" points="469 672" /> <Output id="1361" points="387 675" /> </Outputs> <Catalysts> <Catalyst id="1359" points="437 730" /> </Catalysts> <Properties> <displayName>Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="1398" interactionType="Activate" points="4318 457, 4385 437" position="4351 447" lineWidth="2.0"> <Inputs> <Input id="1093" /> </Inputs> <Outputs> <Output id="1397" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableReaction id="1403" reactomeId="162715" points="485 1010, 717 938, 3124 703" position="717 938" lineWidth="1.0"> <Inputs> <Input id="1399" /> </Inputs> <Outputs> <Output id="40" /> </Outputs> <Properties> <displayName>Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="1423" points="2701 867, 2651 856" position="2676 861" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="1414" /> </Inputs> <Outputs> <Output id="980" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1424" points="2572 986, 2596 856" position="2584 921" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="647" /> </Inputs> <Outputs> <Output id="980" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="1425" points="2966 959, 2600 957, 2600 856" position="2600 957" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="649" /> </Inputs> <Outputs> <Output id="980" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="1440" reactomeId="6782685" points="2762 927, 2762 948, 2796 975" position="2762 948" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1441" stoichiometry="3" points="2793 922" /> <Input id="1414" points="2762 902" /> </Inputs> <Outputs> <Output id="644" stoichiometry="3" points="2888 927" /> <Output id="1434" points="2765 978" /> </Outputs> <Catalysts> <Catalyst id="1442" points="2718 938" /> </Catalysts> <Properties> <displayName>EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1555" reactomeId="6787632" points="5379 190, 5336 190, 5291 190" position="5336 190" lineWidth="1.0"> <Inputs> <Input id="1560" /> </Inputs> <Outputs> <Output id="1556" points="5277 215" /> <Output id="1557" points="5245 190" /> </Outputs> <Catalysts> <Catalyst id="1558" points="5335 161" /> </Catalysts> <Properties> <displayName>GMDS dehydrates GDP-Man to GDP-DHDMan</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1561" reactomeId="6787623" points="5180 191, 5112 191, 5069 191" position="5112 191" lineWidth="1.0"> <Inputs> <Input id="1557" /> </Inputs> <Outputs> <Output id="1562" /> </Outputs> <Catalysts> <Catalyst id="1563" points="5033 143" /> </Catalysts> <Properties> <displayName>GFUS dimer epimerises GDP-DHDMan to GDP-KDGal</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1564" reactomeId="6787642" points="4939 190, 4899 190, 4858 190" position="4899 190" lineWidth="1.0"> <Inputs> <Input id="1562" points="4986 190" /> <Input id="1565" points="4966 247" /> <Input id="1568" points="4986 216" /> </Inputs> <Outputs> <Output id="1566" points="4760 241" /> <Output id="1570" points="4815 173" /> </Outputs> <Catalysts> <Catalyst id="1563" points="4995 143" /> </Catalysts> <Properties> <displayName>GFUS dimer reduces GDP-KDGal to GDP-Fuc</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1571" reactomeId="6787540" points="5124 386, 5084 386, 5045 387" position="5084 386" lineWidth="1.0"> <Inputs> <Input id="1589" points="5175 386" /> <Input id="1590" points="5154 406" /> </Inputs> <Outputs> <Output id="1574" points="4991 386" /> <Output id="4510" points="5023 406" /> <Output id="4512" points="5049 426" /> </Outputs> <Catalysts> <Catalyst id="1576" points="5084 354" /> </Catalysts> <Properties> <displayName>FCSK phosphorylates beta-Fuc to Fuc1P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1577" reactomeId="6787533" points="4888 386, 4851 385, 4806 385" position="4851 385" lineWidth="1.0"> <Inputs> <Input id="1574" points="4934 386" /> <Input id="1582" points="4911 406" /> <Input id="4521" points="4883 426" /> </Inputs> <Outputs> <Output id="1566" points="4739 282" /> <Output id="1580" points="4786 406" /> </Outputs> <Catalysts> <Catalyst id="1578" points="4850 342" /> </Catalysts> <Properties> <displayName>FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1587" reactomeId="742345" points="4702 395, 4690 510, 3442 508, 3442 468, 3404 468" position="3442 468" lineWidth="1.0"> <Inputs> <Input id="4529" points="4548 355" /> <Input id="1566" points="4725 282" /> </Inputs> <Outputs> <Output id="4530" points="3381 499" /> <Output id="1062" points="3390 420" /> </Outputs> <Catalysts> <Catalyst id="1588" points="3476 469" /> </Catalysts> <Properties> <displayName>SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1591" reactomeId="6787677" points="5357 385, 5306 385, 5250 385" position="5306 385" lineWidth="1.0"> <Inputs> <Input id="1592" /> </Inputs> <Outputs> <Output id="1589" /> </Outputs> <Catalysts> <Catalyst id="1593" points="5305 345" /> </Catalysts> <Properties> <displayName>FUOM isomerises alpha-Fuc to beta-Fuc</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1598" reactomeId="5693925" points="2952 418, 2993 418, 3027 418" position="2993 418" lineWidth="1.0"> <Inputs> <Input id="1599" points="2917 396" /> <Input id="1603" points="2941 421" /> </Inputs> <Outputs> <Output id="1600" points="3064 422" /> <Output id="1063" points="3143 313" /> </Outputs> <Catalysts> <Catalyst id="1601" points="2993 452" /> </Catalysts> <Properties> <displayName>FUT3 transfers L-fucose to Gal1,3GlcNAc</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1605" reactomeId="5693807" points="925 195, 982 194, 1034 194" position="982 194" lineWidth="1.0"> <Inputs> <Input id="1606" points="915 189" /> <Input id="1607" points="921 230" /> </Inputs> <Outputs> <Output id="1608" points="1084 215" /> <Output id="1609" points="1068 176" /> </Outputs> <Catalysts> <Catalyst id="1610" points="982 168" /> </Catalysts> <Properties> <displayName>FUCA1 hydrolyses NGP:1,6-GlcNAc</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2178" reactomeId="6786034" points="2689 180, 2744 180, 2778 181" position="2744 180" lineWidth="1.0"> <Inputs> <Input id="2179" points="2654 204" /> <Input id="2180" points="2654 176" /> </Inputs> <Outputs> <Output id="2181" points="2804 199" /> <Output id="2182" points="2832 178" /> </Outputs> <Catalysts> <Catalyst id="2183" points="2743 141" /> </Catalysts> <Properties> <displayName>CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2555" reactomeId="6786048" points="2238 170, 2284 170, 2325 170" position="2284 170" lineWidth="1.0"> <Inputs> <Input id="2556" points="2205 170" /> <Input id="2559" points="2212 198" /> </Inputs> <Outputs> <Output id="2557" points="2391 170" /> <Output id="2560" points="2385 205" /> </Outputs> <Catalysts> <Catalyst id="2558" points="2282 143" /> </Catalysts> <Properties> <displayName>CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2629" reactomeId="6803761" points="182 151, 182 174, 182 206" position="182 174" lineWidth="1.0"> <Inputs> <Input id="2630" /> </Inputs> <Outputs> <Output id="2631" /> </Outputs> <Catalysts> <Catalyst id="2632" points="154 173" /> </Catalysts> <Properties> <displayName>RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2633" reactomeId="6803771" points="182 272, 182 311, 213 311" position="182 311" lineWidth="1.0"> <Inputs> <Input id="2631" points="182 240" /> <Input id="2634" points="161 264" /> </Inputs> <Outputs> <Output id="2635" points="220 330" /> <Output id="2636" points="245 311" /> <Output id="2639" stoichiometry="2" points="233 284" /> </Outputs> <Catalysts> <Catalyst id="2637" points="151 311" /> </Catalysts> <Properties> <displayName>NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2640" reactomeId="6803789" points="395 323, 428 323, 458 323" position="428 323" lineWidth="1.0"> <Inputs> <Input id="2641" points="381 300" /> <Input id="2642" points="383 335" /> </Inputs> <Outputs> <Output id="2643" points="477 290" /> <Output id="61" points="485 323" /> </Outputs> <Catalysts> <Catalyst id="2644" points="428 276" /> </Catalysts> <Properties> <displayName>AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="2645" points="325 340, 313 336" position="319 338" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="2642" /> </Inputs> <Outputs> <Output id="2636" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="2662" reactomeId="6810464" points="593 1234, 532 1234, 484 1235" position="532 1234" lineWidth="1.0"> <Inputs> <Input id="2663" points="614 1248" /> <Input id="79" points="625 1207" /> </Inputs> <Outputs> <Output id="2664" points="437 1206" /> <Output id="2667" points="438 1234" /> <Output id="4549" stoichiometry="2" points="454 1261" /> </Outputs> <Catalysts> <Catalyst id="2665" points="532 1200" /> </Catalysts> <Properties> <displayName>NUDT14 hydrolyses UDP-Glc to G1P and UMP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="2669" points="2772 902, 2842 1037" position="2807 969" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="1414" /> </Inputs> <Outputs> <Output id="2668" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="2670" points="2993 981, 2883 1037" position="2938 1009" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="649" /> </Inputs> <Outputs> <Output id="2668" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="2671" points="2744 1005, 2817 1037" position="2780 1021" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="1434" /> </Inputs> <Outputs> <Output id="2668" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="2672" points="3420 961, 3347 1012, 2921 1054" position="3347 1012" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="245" /> </Inputs> <Outputs> <Output id="2668" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="2673" points="2630 1018, 2784 1048" position="2707 1033" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="647" /> </Inputs> <Outputs> <Output id="2668" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="2985" reactomeId="8850594" points="2858 1208, 2909 1208, 2968 1208" position="2909 1208" lineWidth="1.0"> <Inputs> <Input id="3402" points="2651 1208" /> <Input id="3404" points="2842 1226" /> </Inputs> <Outputs> <Output id="2987" points="3003 1245" /> <Output id="2988" points="3025 1208" /> </Outputs> <Catalysts> <Catalyst id="2990" points="2909 1156" /> </Catalysts> <Properties> <displayName>Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2991" reactomeId="8853379" points="2470 1208, 2420 1208, 2386 1208" position="2420 1208" lineWidth="1.0"> <Inputs> <Input id="3402" points="2530 1208" /> <Input id="3405" points="2468 1220" /> </Inputs> <Outputs> <Output id="2993" points="2334 1245" /> <Output id="2994" points="2310 1208" /> </Outputs> <Catalysts> <Catalyst id="2999" points="2420 1179" /> </Catalysts> <Properties> <displayName>ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3354" reactomeId="8855711" points="5555 97, 5555 96, 5591 96" position="5555 96" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3355" points="5498 37" /> <Input id="3356" points="5516 97" /> </Inputs> <Outputs> <Output id="3357" /> </Outputs> <Properties> <displayName>PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="3373" interactionType="Activate" points="2189 1208, 2092 1208" position="2140 1208" lineWidth="2.0"> <Inputs> <Input id="2994" /> </Inputs> <Outputs> <Output id="3335" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableReaction id="3389" reactomeId="8855954" points="4486 204, 4486 229, 4486 253" position="4486 229" lineWidth="1.0"> <Inputs> <Input id="3390" points="4489 173" /> <Input id="3397" points="4469 200" /> </Inputs> <Outputs> <Output id="3392" points="4486 296" /> <Output id="3399" points="4509 265" /> </Outputs> <Catalysts> <Catalyst id="3393" points="4523 229" /> </Catalysts> <Properties> <displayName>B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3407" reactomeId="8867288" points="2737 1059, 2709 1059, 2653 1059" position="2709 1059" lineWidth="1.0"> <Inputs> <Input id="3408" points="2822 1132" /> <Input id="2668" points="2784 1059" /> </Inputs> <Outputs> <Output id="3406" /> </Outputs> <Catalysts> <Catalyst id="3403" points="2709 1085" /> </Catalysts> <Properties> <displayName>OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3413" reactomeId="446207" points="1598 574, 1669 574, 1712 574" position="1669 574" lineWidth="1.0"> <Inputs> <Input id="23" points="1401 572" /> <Input id="34" points="1541 663" /> </Inputs> <Outputs> <Output id="13" points="1814 657" /> <Output id="3416" points="1739 555" /> </Outputs> <Catalysts> <Catalyst id="3414" points="1670 658" /> </Catalysts> <Properties> <displayName>ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3518" reactomeId="1022127" points="2592 1087, 2592 1114, 2590 1181" position="2592 1114" lineWidth="1.0" reactionType="Uncertain Process"> <Inputs> <Input id="3406" /> </Inputs> <Outputs> <Output id="3402" /> </Outputs> <Properties> <displayName>Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3659" reactomeId="9909159" points="142 490, 143 538, 143 578" position="143 538" lineWidth="1.0"> <Inputs> <Input id="3660" points="113 486" /> <Input id="3661" points="142 463" /> </Inputs> <Outputs> <Output id="67" points="250 598" /> <Output id="3662" points="116 606" /> <Output id="3665" points="105 582" /> </Outputs> <Catalysts> <Catalyst id="3663" points="184 538" /> </Catalysts> <Properties> <displayName>HK1 phosphorylates Mannose to Man6P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4014" reactomeId="9937298" points="534 629, 566 629, 593 629" position="566 629" lineWidth="1.0"> <Inputs> <Input id="1358" points="513 649" /> <Input id="4015" points="504 591" /> </Inputs> <Outputs> <Output id="4016" points="614 591" /> <Output id="4017" points="622 653" /> <Output id="4020" points="567 590" /> </Outputs> <Catalysts> <Catalyst id="4018" points="566 672" /> </Catalysts> <Properties> <displayName>DHRSX oxidizes polyprenol to polyprenal</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4064" reactomeId="9937295" points="686 629, 719 629, 751 629" position="719 629" lineWidth="1.0"> <Inputs> <Input id="4017" points="656 653" /> <Input id="1392" points="759 590" /> <Input id="4067" points="688 590" /> </Inputs> <Outputs> <Output id="1393" points="850 584" /> <Output id="4065" points="777 649" /> </Outputs> <Catalysts> <Catalyst id="1394" points="719 672" /> </Catalysts> <Properties> <displayName>SRD5A3 reduces polyprenal to dolichal</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4154" reactomeId="9937340" points="834 631, 865 631, 898 631" position="865 631" lineWidth="1.0"> <Inputs> <Input id="4065" points="812 649" /> <Input id="1392" points="798 590" /> <Input id="4067" points="709 578" /> </Inputs> <Outputs> <Output id="1393" points="886 590" /> <Output id="44" points="924 649" /> </Outputs> <Catalysts> <Catalyst id="4018" points="594 695, 630 711, 866 711" /> </Catalysts> <Properties> <displayName>DHRSX reduces dolichal to dolichol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4634" reactomeId="964759" points="2335 419, 2393 417, 2406 417" position="2393 417" lineWidth="1.0"> <Inputs> <Input id="4635" /> </Inputs> <Outputs> <Output id="4636" points="2452 381" /> <Output id="1004" stoichiometry="3" points="2460 428" /> </Outputs> <Catalysts> <Catalyst id="1006" points="2394 454" /> </Catalysts> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of Asparagine N-linked glycosylation, Defective ALG1 causes CDG-1k, Defective ALG11 causes CDG-1p, Defective ALG2 causes CDG-1i, Defective DPAGT1 causes CDG-1j, CMSTA2, Defective GFPT1 causes CMSTA1, Defective MPI causes MPI-CDG, Defective PMM2 causes PMM2-CDG, Defective ALG12 causes CDG-1g, Defective ALG3 causes CDG-1d, Defective ALG6 causes CDG-1c, Defective ALG8 causes CDG-1h, Defective ALG9 causes CDG-1l, Defective DPM1 causes DPM1-CDG, Defective DPM2 causes DPM2-CDG, Defective DPM3 causes DPM3-CDG, Defective MPDU1 causes CDG-1f, Defective RFT1 causes CDG-1n, Defective DHDDS causes RP59, Defective DOLK causes DOLK-CDG, Defective SRD5A3 causes SRD5A3-CDG, KHRZ, Defective B4GALT1 causes CDG-2d, Defective MAN1B1 causes MRT15, Defective MGAT2 causes CDG-2a, Defective MOGS causes CDG-2b, and Defective ALG14 causes ALG14-CMS (548980)
