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Details on Person TECR,TECRL dehydrogenate TOD-CoA to ST-CoA

Class:Id	Reaction:548831
_displayName	TECR,TECRL dehydrogenate TOD-CoA to ST-CoA
_doRelease	TRUE
_timestamp	2024-03-20 19:03:11
authored	[InstanceEdit:548846] D'Eustachio, P, 2010-03-14
catalystActivity	[CatalystActivity:548793] very-long-chain fatty acyl-CoA dehydrogenase activity of TECR,TECRL [endoplasmic reticulum membrane]
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:548837] D'Eustachio, P, 2010-03-14
edited	[InstanceEdit:5678222] D'Eustachio, Peter, 2015-02-21
input	[SimpleEntity:548809] TOD-CoA [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:548718] Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade
modified	[InstanceEdit:548844] D'Eustachio, P, 2010-03-14 [InstanceEdit:548845] D'Eustachio, P, 2010-03-14 [InstanceEdit:5676204] Jassal, Bijay, 2015-02-19 [InstanceEdit:5678221] D'Eustachio, Peter, 2015-02-21 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9865937] D'Eustachio, Peter, 2024-03-20
name	TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (2E)-octadecenoyl-CoA + H(+) + NADPH => NADP(+) + octadecanoyl-CoA trans-octadec-2-enoyl-CoA + NADPH + H+ => stearoyl-CoA + NADP+
output	[SimpleEntity:428139] ST-CoA [cytosol] [SimpleEntity:29366] NADP+ [cytosol]
precedingEvent	[Reaction:5676637] PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA [Homo sapiens] [Reaction:548818] HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA [Homo sapiens]
releaseDate	2008-12-17
reviewed	[InstanceEdit:5678222] D'Eustachio, Peter, 2015-02-21
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5676160] Jassal, Bijay, 2015-02-19
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105378] R-HSA-548831.4
summation	[Summation:548804] Trans-2,3-enoyl-CoA reductase (TECR) catalyzes the reaction ...
(hasEvent)	[Pathway:75876] Synthesis of very long-chain fatty acyl-CoAs [Homo sapiens]
(precedingEvent)	[Reaction:5690565] SCD desaturates ST-CoA to OLE-CoA [Homo sapiens] [Reaction:8847579] SCD5 desaturates ST-CoA to OLE-CoA [Homo sapiens]
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No pathways have been reviewed or authored by TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (548831)