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Details on Person ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA

Class:IdReaction:548815
_displayNameELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA
_doReleaseTRUE
_timestamp2024-04-12 19:41:42
authored[InstanceEdit:548846] D'Eustachio, P, 2010-03-14
catalystActivity[CatalystActivity:548807] fatty acid elongase activity of ELOVL7 [endoplasmic reticulum membrane]
catalystActivityReference[CatalystActivityReference:9643379] fatty acid elongase activity of ELOVL7 [endoplasmic reticulum membrane] Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism
compartment[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:548837] D'Eustachio, P, 2010-03-14
edited[InstanceEdit:548852] D'Eustachio, P, 2010-03-14
input[SimpleEntity:548794] ICS-CoA [cytosol]
[SimpleEntity:29508] Mal-CoA [cytosol]
[SimpleEntity:70106] H+ [cytosol]
internalReviewed[InstanceEdit:9907566] D'Eustachio, Peter, 2024-04-12
isChimericFALSE
literatureReference[LiteratureReference:548733] Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism
modified[InstanceEdit:548844] D'Eustachio, P, 2010-03-14
[InstanceEdit:548845] D'Eustachio, P, 2010-03-14
[InstanceEdit:827349] Matthews, L, 2010-05-27
[InstanceEdit:5676204] Jassal, Bijay, 2015-02-19
[InstanceEdit:5678221] D'Eustachio, Peter, 2015-02-21
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9865937] D'Eustachio, Peter, 2024-03-20
[InstanceEdit:9907565] D'Eustachio, Peter, 2024-04-12
[InstanceEdit:9907580] D'Eustachio, Peter, 2024-04-12
nameELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA
eicosanoyl-CoA + H(+) + malonyl-CoA => 3-oxodocosanoyl-CoA + CO2 + CoA
arachidoyl-CoA + malonyl-CoA => 3-oxobehenoyl-CoA + CO2 + CoASH [ELOVL7]
output[SimpleEntity:76194] CoA-SH [cytosol]
[SimpleEntity:113528] CO2 [cytosol]
[SimpleEntity:548829] 3ODC-CoA [cytosol]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2010-06-15
reviewed[InstanceEdit:5678222] D'Eustachio, Peter, 2015-02-21
[InstanceEdit:9907581] Hill, David P, 2024-04-12
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5676160] Jassal, Bijay, 2015-02-19
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105629] R-HSA-548815.4
structureModified[InstanceEdit:9865937] D'Eustachio, Peter, 2024-03-20
summation[Summation:548803] Elongation of very long chain fatty acids protein 7 (ELOVL7)...
(hasEvent)[Pathway:75876] Synthesis of very long-chain fatty acyl-CoAs [Homo sapiens]
(updatedInstance)[_UpdateTracker:9910978] Update Tracker - [Reaction:548815] ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA - v89:[addInput]
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