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Details on Person Acyl-CoA synthetase long-chain family member 4 (ACSL4) assoc...
| Class:Id | Summation:548799 |
|---|---|
| _displayName | Acyl-CoA synthetase long-chain family member 4 (ACSL4) assoc... |
| _timestamp | 2015-02-21 22:32:06 |
| created | [InstanceEdit:548837] D'Eustachio, P, 2010-03-14 |
| modified | [InstanceEdit:548844] D'Eustachio, P, 2010-03-14 [InstanceEdit:5676204] Jassal, Bijay, 2015-02-19 [InstanceEdit:5678221] D'Eustachio, Peter, 2015-02-21 |
| text | Acyl-CoA synthetase long-chain family member 4 (ACSL4) associated with the endoplasmic reticulum membrane catalyses the conjugation of arachidonate (AA) with CoA to form arachidonyl-CoA (AA-CoA) (Longo et al. 2003, Meloni et al. 2003). By similarity, ACSL3 can also preferentially conjugate CoA on to AA (Yao & Ye 2008). These enzymes are involved in the activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. |
| (summation) | [Reaction:548843] ACSL3,4 ligate CoA to AA to form AA-CoA [Homo sapiens] |
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No pathways have been reviewed or authored by Acyl-CoA synthetase long-chain family member 4 (ACSL4) assoc... (548799)
