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Details on Person UniProt:Q13630 GFUS
Class:Id
ReferenceGeneProduct:54728
_chainChangeLog
chain:1-321 added on Fri February 6 2015
_displayName
UniProt:Q13630 GFUS
_timestamp
2025-02-21 19:06:38
chain
chain:1-321
checksum
94BB1FF61658007C
comment
FUNCTION Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.CATALYTIC ACTIVITY GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)PATHWAY Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.SUBUNIT Homodimer.INTERACTION Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
description
recommendedName: fullName evidence="5"GDP-L-fucose synthase ecNumber evidence="3"1.1.1.271 alternativeName: GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase alternativeName: Protein FX alternativeName: Red cell NADP(H)-binding protein alternativeName: Short-chain dehydrogenase/reductase family 4E member 1
geneName
GFUS SDR4E1 TSTA3
identifier
Q13630
isSequenceChanged
FALSE
keyword
3D-structure Direct protein sequencing Isomerase Multifunctional enzyme NADP Oxidoreductase Proteomics identification Reference proteome
