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Details on Person UniProt:P05160 F13B
| Class:Id | ReferenceGeneProduct:54562 |
|---|---|
| _chainChangeLog | signal peptide:1-20 added on Fri February 6 2015;chain:21-661 added on Fri February 6 2015 |
| _displayName | UniProt:P05160 F13B |
| _timestamp | 2025-02-21 19:27:37 |
| chain | signal peptide:1-20 chain:21-661 |
| checksum | 57A2FD2A0E35B812 |
| comment | FUNCTION The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.SUBUNIT Tetramer of two A chains (F13A1) and two B (F13B) chains.SUBCELLULAR LOCATION The disease is caused by variants affecting the gene represented in this entry.ONLINE INFORMATION Factor XIII entry |
| description | recommendedName: Coagulation factor XIII B chain alternativeName: Fibrin-stabilizing factor B subunit alternativeName: Protein-glutamine gamma-glutamyltransferase B chain alternativeName: Transglutaminase B chain |
| geneName | F13B |
| identifier | P05160 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Blood coagulation Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hemostasis Proteomics identification Reference proteome Repeat Secreted Signal Sushi |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | F13B |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996557] ENSEMBL:ENSG00000143278 F13B [Homo sapiens] |
| secondaryIdentifier | F13B_HUMAN A8K3E5 Q5VYL5 |
| sequenceLength | 661 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:140605] F13B [extracellular region] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:P05160 F13B (54562)
