Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9UNN8 PROCR
| Class:Id | ReferenceGeneProduct:54386 |
|---|---|
| _chainChangeLog | signal peptide:1-17 added on Sat February 7 2015;chain:18-238 added on Sat February 7 2015 |
| _displayName | UniProt:Q9UNN8 PROCR |
| _timestamp | 2024-11-03 19:51:06 |
| chain | signal peptide:1-17 chain:18-238 |
| checksum | EA7F0658CD19695C |
| comment | FUNCTION Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.INTERACTION Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.PTM N-glycosylated.PTM A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. |
| description | recommendedName: Endothelial protein C receptor alternativeName: Activated protein C receptor shortName: APC receptor alternativeName: Endothelial cell protein C receptor cdAntigenNameCD201/cdAntigenName |
| geneName | PROCR EPCR |
| identifier | Q9UNN8 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Blood coagulation Disulfide bond Glycoprotein Hemostasis Membrane Proteomics identification Receptor Reference proteome Signal Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PROCR |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997145] ENSEMBL:ENSG00000101000 PROCR [Homo sapiens] |
| secondaryIdentifier | EPCR_HUMAN B2RC04 Q14218 Q6IB56 Q96CB3 Q9ULX1 |
| sequenceLength | 238 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5591027] PROCR [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:5610109] PROCR(18-?) [extracellular region] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9UNN8 PROCR (54386)
