Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:G3UYX5 Rgs22

Class:IdReferenceGeneProduct:5433711
_chainChangeLogchain:1-1258 added on Fri February 6 2015
_displayNameUniProt:G3UYX5 Rgs22
_timestamp2023-11-03 16:46:53
chainchain:1-1258
checksumE3C90E88FE6E0901
commentFUNCTION Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.SUBUNIT Interacts with GNA11, GNA12 and GNA13.SUBCELLULAR LOCATION Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus.TISSUE SPECIFICITY Expressed testis, including in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).
created[InstanceEdit:5433710] Weiser, JD
descriptionrecommendedName: Regulator of G-protein signaling 22
geneNameRgs22
identifierG3UYX5
isSequenceChangedFALSE
keywordCoiled coil
Cytoplasm
Nucleus
Reference proteome
Repeat
Signal transduction inhibitor
modified[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9819394] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameRgs22
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierRGS22_MOUSE
sequenceLength1258
species[Species:48892] Mus musculus
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No pathways have been reviewed or authored by UniProt:G3UYX5 Rgs22 (5433711)