Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P32519 ELF1
| Class:Id | ReferenceGeneProduct:54248 |
|---|---|
| _chainChangeLog | chain:1-619 added on Sat February 7 2015 |
| _displayName | UniProt:P32519 ELF1 |
| _timestamp | 2024-11-03 20:14:16 |
| chain | chain:1-619 |
| checksum | FA0A51B3965616F3 |
| comment | FUNCTION Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.SUBUNIT Binds to the underphosphorylated form of RB. May interact with other transcription factors in order to regulate specific genes. Interacts with RUNX1.INTERACTION In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.SIMILARITY Belongs to the ETS family. |
| description | recommendedName: ETS-related transcription factor Elf-1 alternativeName: E74-like factor 1 |
| geneName | ELF1 |
| identifier | P32519 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Activator Alternative splicing DNA-binding Nucleus Phosphoprotein Proteomics identification Reference proteome Transcription Transcription regulation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ELF1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9001134] ENSEMBL:ENSG00000120690 ELF1 [Homo sapiens] |
| secondaryIdentifier | ELF1_HUMAN B4E2I5 E9PDQ9 Q8N6F6 Q9UDE1 |
| sequenceLength | 619 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8975545] UniProt:P32519-1 ELF1 [Homo sapiens] [ReferenceIsoform:8975546] UniProt:P32519-2 ELF1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:8938902] ELF1 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P32519 ELF1 (54248)
