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Details on Person UniProt:Q99856 ARID3A
| Class:Id | ReferenceGeneProduct:53892 |
|---|---|
| _chainChangeLog | chain:1-593 added on Fri February 6 2015 |
| _displayName | UniProt:Q99856 ARID3A |
| _timestamp | 2024-11-03 20:08:51 |
| chain | chain:1-593 |
| checksum | 4D09131E168A2880 |
| comment | FUNCTION Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.SUBUNIT Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK.INTERACTION Shuttles between nucleus and cytoplasm.TISSUE SPECIFICITY Widely expressed, with highest expression in skeletal muscle, thalamus, and colon.INDUCTION By p53/TP53 following DNA damage. |
| description | recommendedName: AT-rich interactive domain-containing protein 3A shortName: ARID domain-containing protein 3A alternativeName: B-cell regulator of IgH transcription shortName: Bright alternativeName: Dead ringer-like protein 1 alternativeName: E2F-binding protein 1 |
| geneName | ARID3A DRIL1 DRIL3 DRX E2FBP1 |
| identifier | Q99856 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cytoplasm DNA-binding Isopeptide bond Nucleus Phosphoprotein Proteomics identification Reference proteome Transcription Transcription regulation Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ARID3A |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:6791367] ENSEMBL:ENSG00000116017 ARID3A [Homo sapiens] |
| secondaryIdentifier | ARI3A_HUMAN Q5I858 Q6P9C6 Q8IZA7 Q8N4Z3 |
| sequenceLength | 593 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:3782552] ARID3A [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3782579] monoSUMO1-K398-ARID3A [nucleoplasm] [Homo sapiens] |
| (referenceSequence) | [GroupModifiedResidue:3782587] sumoylated lysine (monoSUMO1 [nucleoplasm]) at 398 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q99856 ARID3A (53892)
