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Details on Person PP1 dephosphorylates phosphorylated TIM in the complex with PER and DCO

Class:Id	Reaction:538832
_displayName	PP1 dephosphorylates phosphorylated TIM in the complex with PER and DCO
_doRelease	TRUE
_timestamp	2018-03-09 00:16:07
authored	[InstanceEdit:538852] Williams, MG, 2010-03-08
catalystActivity	[CatalystActivity:881981] protein serine/threonine phosphatase activity of PP1:Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:538896] Williams, MG, 2010-03-08
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:881971] /figures/DrosCircClockC39.jpg
input	[Complex:882002] PP1:Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:432504] Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)
modified	[InstanceEdit:882016] Williams, MG, 2010-06-28 [InstanceEdit:909539] Williams, MG, 2010-07-07 [InstanceEdit:912304] Williams, MG, 2010-07-08 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024541] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PP1 dephosphorylates phosphorylated TIM in the complex with PER and DCO
output	[Complex:881912] TIM:Phospho (multi-site 2) PER:DCO [cytosol] [Drosophila melanogaster] [DefinedSet:432645] PP1 [cytosol] [Drosophila melanogaster] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:538824] PP1 binds to phosphorylated TIM in complex with PER [Drosophila melanogaster] [Reaction:432535] TIM is phosphorylated by CK2 [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:909536] Edery, I, 2010-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8882730] R-DME-538832.4
summation	[Summation:432563] The protein phosphatase, PP1, dephosphorylates and stabilise...
(hasEvent)	[Pathway:538898] Dephosphorylation of TIM [Drosophila melanogaster]
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