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Details on Person SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]

Class:Id	Complex:5387378
_displayName	SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
_timestamp	2014-11-20 04:22:18
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:5387379] Rothfels, Karen, 2014-04-29
hasComponent	[Complex:5362378] SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Homo sapiens] [Complex:5362361] SYVN1 dimer [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:535496] SYVN1(1-617) [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:535496] SYVN1(1-617) [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:1911545] SEL1L [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:5362350] DERL2 [endoplasmic reticulum membrane] [Homo sapiens] [Complex:5362364] VCP hexamer [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1181251] VCP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1181251] VCP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1181251] VCP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1181251] VCP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1181251] VCP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1181251] VCP [cytosol] [Homo sapiens] [Complex:5362380] SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen] [Homo sapiens] [DefinedSet:5362377] OS9/ERLEC1 [endoplasmic reticulum quality control compartment] [Homo sapiens] [CandidateSet:5358456] SHH variants [endoplasmic reticulum lumen] [Homo sapiens]
isChimeric	FALSE
name	SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5648971] R-HSA-5387378.1
(diseaseEntity)	[EntityFunctionalStatus:9630074] gain_of_function of SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
(input)	[Reaction:5483238] Hh processing variants are ubiquitinated [Homo sapiens]
(output)	[Reaction:5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane [Homo sapiens]
(physicalEntity)	[CatalystActivity:5483235] ubiquitin-protein transferase activity of SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
(updatedInstance)	[_UpdateTracker:9899748] Update Tracker - [Complex:5387378] SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] - v67:[updateContainedComponent]
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No pathways have been reviewed or authored by SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (5387378)