Query author contributions in Reactome
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Details on Person UniProt:Q14565 DMC1
| Class:Id | ReferenceGeneProduct:53768 |
|---|---|
| _chainChangeLog | chain:1-340 added on Sat February 7 2015 |
| _displayName | UniProt:Q14565 DMC1 |
| _timestamp | 2024-11-03 20:09:41 |
| chain | chain:1-340 |
| checksum | 040A6E4CF1FEBFA2 |
| comment | FUNCTION Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.SUBUNIT Double stacked ring-shaped homooctamer (PubMed:15125839). Interacts with BRCA2 (PubMed:20729832). Interacts with the MND1-PSMC3IP heterodimer (By similarity). Interacts with RAD51AP1; the interaction is direct and stimulates DMC1-mediated homologous recombination (PubMed:21307306, PubMed:21903585).INTERACTION Belongs to the RecA family. DMC1 subfamily. |
| description | recommendedName: Meiotic recombination protein DMC1/LIM15 homolog |
| geneName | DMC1 DMC1H LIM15 |
| identifier | Q14565 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing ATP-binding Cell cycle Chromosome DNA-binding Meiosis Nucleotide-binding Nucleus Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | DMC1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8991229] ENSEMBL:ENSG00000100206 DMC1 [Homo sapiens] |
| secondaryIdentifier | DMC1_HUMAN A8K9A2 B4DMW6 Q08AI1 Q99498 Q9UH11 |
| sequenceLength | 340 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:8974241] UniProt:Q14565-1 DMC1 [Homo sapiens] [ReferenceIsoform:8974242] UniProt:Q14565-2 DMC1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:912490] DMC1 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q14565 DMC1 (53768)
