Query author contributions in Reactome

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Details on Person Young, Samuel N

Class:Id	Person:5364098
_displayName	Young, Samuel N
_timestamp	2014-04-21 06:17:11
created	[InstanceEdit:5364231] Shamovsky, V, 2014-04-21
firstname	Samuel N
initial	SN
surname	Young
(author)	[LiteratureReference:5364089] The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism [LiteratureReference:9686453] Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis [LiteratureReference:9686472] Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death [LiteratureReference:9686475] The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis [LiteratureReference:9687627] Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL [LiteratureReference:9697389] Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues [LiteratureReference:9697409] Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies [LiteratureReference:9697415] Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3 [LiteratureReference:9697417] MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis [LiteratureReference:9698712] Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop List all 13 refering instances
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No pathways have been reviewed or authored by Young, Samuel N (5364098)