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Details on Person SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen]

Class:Id	Complex:5362380
_displayName	SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen]
_timestamp	2014-11-20 04:11:16
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:5362381] Rothfels, Karen, 2014-04-15
disease	[Disease:5358398] holoprosencephaly
hasComponent	[DefinedSet:5362377] OS9/ERLEC1 [endoplasmic reticulum quality control compartment] [Homo sapiens] [CandidateSet:5358456] SHH variants [endoplasmic reticulum lumen] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:5387398] Rothfels, Karen, 2014-04-29
name	SHH processing variants:OS9/ERLEC1
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5648416] R-HSA-5362380.1
(diseaseEntity)	[EntityFunctionalStatus:9630076] gain_of_function of SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen]
(hasComponent)	[Complex:5387378] SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] [Homo sapiens]
(input)	[Reaction:5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane [Homo sapiens]
(output)	[Reaction:5362450] Hh processing variants bind lectins [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9899852] Update Tracker - [Complex:5362380] SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen] - v67:[updateContainedComponent]
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No pathways have been reviewed or authored by SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen] (5362380)