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Details on Person The complex consisting of selenocysteinyl (Sec) transfer RNA...
| Class:Id | Summation:5359355 |
|---|---|
| _displayName | The complex consisting of selenocysteinyl (Sec) transfer RNA... |
| _timestamp | 2015-08-30 00:39:40 |
| created | [InstanceEdit:5359359] Williams, MG, 2014-04-09 |
| modified | [InstanceEdit:6793107] D'Eustachio, Peter, 2015-08-30 |
| text | The complex consisting of selenocysteinyl (Sec) transfer RNA (tRNA) for Sec (Sec-tRNASec), selenocysteine-specific elongation factor (EEFSEC) aka SelB, selenocysteine insertion sequence-binding protein 2 (SECISBP2) aka SBP2 and GTP interacts with the 80S ribosomal protein complex (80S:Met-tRNAi:mRNA). This triggers the hydrolysis of GTP (to GDP) by EEFSEC and delivery of Sec-tRNASec to the ribosomal A site. Before the Sec residue is inserted into the nascent polypeptide chain, EEFSEC:GDP is released. This reaction is inferred from events occurring in rats. |
| (summation) | [Reaction:5333615] 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC [Homo sapiens] |
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No pathways have been reviewed or authored by The complex consisting of selenocysteinyl (Sec) transfer RNA... (5359355)
