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Details on Person One step at a time: endoplasmic reticulum-associated degradation

Class:IdLiteratureReference:5359171
_displayNameOne step at a time: endoplasmic reticulum-associated degradation
_timestamp2014-04-08 18:31:53
author[Person:5359172] Vembar, Shruthi S
[Person:5359169] Brodsky, Jeffrey L
created[InstanceEdit:5359170] Rothfels, Karen, 2014-04-08
journalNat. Rev. Mol. Cell Biol.
pages944-57
pubMedIdentifier19002207
titleOne step at a time: endoplasmic reticulum-associated degradation
volume9
year2008
(literatureReference)[Reaction:5362437] C-terminal Hh fragments are bound by lectins [Homo sapiens]
[Reaction:5362441] C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane [Homo sapiens]
[Reaction:5362450] Hh processing variants bind lectins [Homo sapiens]
[Reaction:5362459] VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol [Homo sapiens]
[Reaction:5387389] Hh processing variants are translocated to the cytosol in a VCP-dependent manner [Homo sapiens]
[Reaction:8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol [Homo sapiens]
[Reaction:8866551] CFTR binds components of the ERAD machinery for ubiquitination and degradation [Homo sapiens]
[Reaction:8866854] VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol [Homo sapiens]
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