Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2

Class:Id	Reaction:5358484
_displayName	DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2
_doRelease	TRUE
_timestamp	2016-11-10 00:54:39
authored	[InstanceEdit:5358471] D'Eustachio, Peter, 2014-03-28
catalystActivity	[CatalystActivity:5358474] diphthine methyl ester synthase activity of DPH5 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643414] diphthine synthase activity of DPH5 [cytosol] The post-translational trimethylation of diphthamide studied in vitro
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5358471] D'Eustachio, Peter, 2014-03-28
edited	[InstanceEdit:5358471] D'Eustachio, Peter, 2014-03-28
input	[EntityWithAccessionedSequence:5358478] aminocarboxypropyl EEF2 [cytosol] [Homo sapiens] [SimpleEntity:71284] AdoMet [cytosol] [SimpleEntity:71284] AdoMet [cytosol] [SimpleEntity:71284] AdoMet [cytosol] [SimpleEntity:71284] AdoMet [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:5308144] Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2 [LiteratureReference:5358481] DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae [LiteratureReference:5358482] The post-translational trimethylation of diphthamide studied in vitro
modified	[InstanceEdit:5367017] D'Eustachio, Peter, 2014-04-25 [InstanceEdit:5643727] D'Eustachio, Peter, 2014-11-17 [InstanceEdit:5643868] D'Eustachio, Peter, 2014-11-18 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2
output	[SimpleEntity:71285] AdoHcy [cytosol] [SimpleEntity:71285] AdoHcy [cytosol] [SimpleEntity:71285] AdoHcy [cytosol] [SimpleEntity:71285] AdoHcy [cytosol] [EntityWithAccessionedSequence:5367025] Me-diphthine EEF2 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:5358494] DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 [Homo sapiens]
releaseDate	2013-12-04
reviewed	[InstanceEdit:5643867] Liu, Shihui, 2014-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5622547] R-HSA-5358484.4
summation	[Summation:5358477] Cytosolic diphthamide biosynthesis protein 5 (DPH5) transfer...
(hasEvent)	[Pathway:5358493] Synthesis of diphthamide-EEF2 [Homo sapiens]
(precedingEvent)	[Reaction:5367022] DPH7 hydrolyzes a methyl group on Me-diphthine EEF2 [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (5358484)