Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person holoprosencephaly

Class:Id	Disease:5358398
_displayName	holoprosencephaly
_timestamp	2014-03-28 21:22:35
created	[InstanceEdit:5358399] Rothfels, Karen, 2014-03-28
identifier	4621
name	holoprosencephaly
referenceDatabase	[ReferenceDatabase:1247631] DOID
synonym	Holoprosencephaly sequence (disorder)
(disease)	[FailedReaction:5358460] HPE SHH variants don't undergo autoproteolytic cleavage [Homo sapiens] [Reaction:5362450] Hh processing variants bind lectins [Homo sapiens] [Pathway:5362768] Hh mutants are degraded by ERAD [Homo sapiens] [Reaction:5387386] Hh processing variants are recruited to SEL1:SYVN at the ER membrane [Homo sapiens] [Reaction:5387389] Hh processing variants are translocated to the cytosol in a VCP-dependent manner [Homo sapiens] [Pathway:5387390] Hh mutants abrogate ligand secretion [Homo sapiens] [BlackBoxEvent:5387392] processing defective Hh variants are degraded by the proteasome [Homo sapiens] [BlackBoxEvent:5440854] SHH variants that don't undergo processing are shunted into the ERAD pathway [Homo sapiens] [Reaction:5483238] Hh processing variants are ubiquitinated [Homo sapiens] [EntityWithAccessionedSequence:5358401] SHH(24-462) W117R [endoplasmic reticulum lumen] [Homo sapiens] List all 59 refering instances
[Change default viewing format]

No pathways have been reviewed or authored by holoprosencephaly (5358398)