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Details on Person Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation

Class:IdLiteratureReference:5357891
_displayNameCrystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation
_timestamp2014-03-26 14:35:42
author[Person:5357961] Zheng, Chao
[Person:2408404] Kabaleeswaran, Venkataraman
[Person:2395976] Wang, Yaya
[Person:2395985] Cheng, Genhong
[Person:1237368] Wu, H
created[InstanceEdit:5357856] Shamovsky, V, 2014-03-26
journalMol. Cell
pages101-13
pubMedIdentifier20385093
titleCrystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation
volume38
year2010
(literatureReference)[Complex:5357866] TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] [Homo sapiens]
[Complex:5634184] TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] [Homo sapiens]
[Summation:74302] Once the TNF-α:TNFR1:TRADD:RIPK1 complex has been formed the...
[Summation:5357942] Activation of tumor necrosis factor receptor 1 (TNFR1) stimu...
[Summation:5657915] TNF-induced NFkappaB activates a group of gene products incl...
[BlackBoxEvent:5357757] BIRC(cIAP1/2) ubiquitinates RIPK1 [Homo sapiens]
[Reaction:5357780] TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) [Homo sapiens]
[Reaction:5634221] TRAF1 binds TRAF2 within TNFR1 signaling complex [Homo sapiens]
[RegulationReference:9641442] Positive regulation by 'TRAF1 [cytosol]' Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation
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