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Details on Person LUBAC ubiquitinates RIP1

Class:IdReaction:5357822
_displayNameLUBAC ubiquitinates RIP1
_doReleaseFALSE
_timestamp2016-07-15 23:48:55
catalystActivity[CatalystActivity:5357871] ubiquitin-protein transferase activity of TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane]
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:5357856] Shamovsky, V, 2014-03-26
input[Complex:5357749] TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5357781] Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling
modified[InstanceEdit:5364240] Shamovsky, V, 2014-04-21
[InstanceEdit:5626948] Shamovsky, V, 2014-10-14
[InstanceEdit:5634234] Shamovsky, V, 2014-11-03
[InstanceEdit:5643755] Shamovsky, Veronica, 2014-11-17
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameLUBAC ubiquitinates RIP1
output[Complex:5357756] TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] [Homo sapiens]
[Complex:5357865] LUBAC [cytosol] [Homo sapiens]
precedingEvent
requiredInputComponent[Complex:1234116] UBE2D1,2,3:Ubiquitin [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8880272] R-HSA-5357822.1
summation[Summation:5357935] Receptor-interacting protein 1 (RIPK1) polyubiquitination is...
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No pathways have been reviewed or authored by LUBAC ubiquitinates RIP1 (5357822)