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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:P21918 DRD5

Class:IdReferenceGeneProduct:53424
_chainChangeLogchain:1-477 added on Sat February 7 2015
_displayNameUniProt:P21918 DRD5
_timestamp2026-02-20 21:58:27
chainchain:1-477
checksumBACCB85E5A72F9CA
commentFUNCTION Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.INTERACTION Neuron-specific, localized primarily within limbic regions of the brain.DISEASE Disease susceptibility may be associated with variants affecting the gene represented in this entry.SIMILARITY Belongs to the G-protein coupled receptor 1 family.
descriptionrecommendedName: D(1B) dopamine receptor alternativeName: D(5) dopamine receptor alternativeName: D1beta dopamine receptor alternativeName: Dopamine D5 receptor
geneNameDRD5
DRD1B
DRD1L2
identifierP21918
isSequenceChangedFALSE
keyword3D-structure
Cell membrane
Disulfide bond
Dystonia
G-protein coupled receptor
Glycoprotein
Lipoprotein
Membrane
Palmitate
Proteomics identification
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9862192] Weiser, Joel, 2024-02-26
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameDRD5
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8998857] ENSEMBL:ENSG00000169676 DRD5 [Homo sapiens]
secondaryIdentifierDRD5_HUMAN
B2R9S3
Q8NEQ8
sequenceLength477
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:390832] DRD5 [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:P21918 DRD5 (53424)