Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P21728 DRD1
| Class:Id | ReferenceGeneProduct:53402 |
|---|---|
| _chainChangeLog | chain:1-446 added on Fri February 6 2015 |
| _displayName | UniProt:P21728 DRD1 |
| _timestamp | 2026-02-20 22:20:52 |
| chain | chain:1-446 |
| checksum | 64E062D765D0DBA7 |
| comment | FUNCTION Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Forms heterotetramers with DRD3 to potentiate beta-arrestin recruitment and mediate locomotor activity.SUBUNIT Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD2. Interacts with DORIP1. Interacts with DRD3 (By similarity).INTERACTION Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.TISSUE SPECIFICITY Detected in caudate, nucleus accumbens and in the olfactory tubercle.SIMILARITY Belongs to the G-protein coupled receptor 1 family. |
| description | recommendedName: D(1A) dopamine receptor alternativeName: Dopamine D1 receptor |
| geneName | DRD1 |
| identifier | P21728 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cell membrane Cell projection Disulfide bond Endoplasmic reticulum G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Proteomics identification Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | DRD1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8987787] ENSEMBL:ENSG00000184845 DRD1 [Homo sapiens] |
| secondaryIdentifier | DRD1_HUMAN B2RA44 Q4QRJ0 |
| sequenceLength | 446 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:390853] DRD1 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P21728 DRD1 (53402)
