Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person Dnmt3a:Dnmt3l methylates cytosine in DNA
Class:Id Reaction:5336316 _displayName Dnmt3a:Dnmt3l methylates cytosine in DNA _doRelease TRUE _timestamp 2015-06-02 02:06:31 authored [InstanceEdit:5334182] May, B, 2014-02-22 catalystActivity [CatalystActivity:5336214] DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates of Dnmt3a:Dnmt3l:Chromatin [nucleoplasm] compartment [Compartment:7660] nucleoplasm created [InstanceEdit:5336392] May, B, 2014-03-02 edited [InstanceEdit:5334182] May, B, 2014-02-22 input [Complex:5334103] Dnmt3a:Dnmt3l:Chromatin [nucleoplasm] [Mus musculus] [SimpleEntity:77087] AdoMet [nucleoplasm] isChimeric FALSE literatureReference [LiteratureReference:5336360] Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro [LiteratureReference:5336391] Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L [LiteratureReference:5334112] The N-terminus of histone H3 is required for de novo DNA methylation in chromatin [LiteratureReference:5336210] In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases [LiteratureReference:5336313] In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b [LiteratureReference:5336300] Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a [LiteratureReference:5336267] The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1 [LiteratureReference:5336384] De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases [LiteratureReference:5336271] DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development [LiteratureReference:5336371] Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases [LiteratureReference:5336333] Dynamic CpG island methylation landscape in oocytes and preimplantation embryos [LiteratureReference:5334173] Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail modified [InstanceEdit:5615505] May, Bruce, 2014-07-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name Dnmt3a:Dnmt3l methylates cytosine in DNA output [Complex:5334117] Dnmt3a:Dnmt3l:Chromatin with 5mC [nucleoplasm] [Mus musculus] [SimpleEntity:77502] AdoHcy [nucleoplasm] precedingEvent
releaseDate 2014-09-30 reviewed [InstanceEdit:5615504] Beekman, Renée, Martín-Subero, José I, 2014-07-24 reviewStatus [ReviewStatus:9821382] five stars species [Species:48892] Mus musculus stableIdentifier [StableIdentifier:6781668] R-MMU-5336316.2 summation [Summation:5336361] Dnmt3a methylates the 5 position of cytosine in DNA preferen... (inferredFrom) [Reaction:5334152] DNMT3A:DNMT3L methylates cytosine in DNA [Homo sapiens]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by Dnmt3a:Dnmt3l methylates cytosine in DNA (5336316)
