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Details on Person Uhrf1 binds chromatin with hemimethylC

Class:IdReaction:5336231
_displayNameUhrf1 binds chromatin with hemimethylC
_doReleaseTRUE
_timestamp2014-11-20 02:56:47
authored[InstanceEdit:5334182] May, B, 2014-02-22
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:5336392] May, B, 2014-03-02
edited[InstanceEdit:5334182] May, B, 2014-02-22
input[EntityWithAccessionedSequence:5336220] Uhrf1 [nucleoplasm] [Mus musculus]
[Complex:5336292] Chromatin with hemimethylC [nucleoplasm] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:5336291] Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
[LiteratureReference:5336374] The multi-domain protein Np95 connects DNA methylation and histone modification
[LiteratureReference:5336302] The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
[LiteratureReference:212167] UHRF1 plays a role in maintaining DNA methylation in mammalian cells
modified[InstanceEdit:5339616] May, B, 2014-03-07
[InstanceEdit:5615505] May, Bruce, 2014-07-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameUhrf1 binds chromatin with hemimethylC
output[Complex:5336397] Uhrf1:Chromatin with hemimethylC [nucleoplasm] [Mus musculus]
releaseDate2014-09-30
reviewed[InstanceEdit:5615504] Beekman, Renée, Martín-Subero, José I, 2014-07-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:5645169] R-MMU-5336231.2
summation[Summation:5339603] Uhrf1 (also known as Np95) preferentially binds hemi-methyla...
(inferredFrom)[Reaction:5334099] UHRF1 binds chromatin with hemimethylated cytosine [Homo sapiens]
(precedingEvent)[Reaction:5336365] Uhrf1:Chromatin binds Dnmt1 [Mus musculus]
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No pathways have been reviewed or authored by Uhrf1 binds chromatin with hemimethylC (5336231)